Platelet Function and Blood Coagulation
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Questions and Answers

What is the function of Gp2b/3a on the surface of platelets in the process of platelet aggregation?

It helps in the aggregation of platelets by forming a bond with fibrinogen.

What is the effect of flipping phosphatidylserine on the surface of platelets?

It gives a negative charge to platelets, leading to the activation of the clotting pathway.

What is the sequence of platelet aggregation?

Platelets with Gp2b/3a on their surface are attached by fibrinogen, leading to the aggregation of all platelets.

What is the mnemonic device used to remember the 'P' factors involved in platelet activation?

<p>All P things and all Factors.</p> Signup and view all the answers

What is the role of tissue factor in the clotting pathway?

<p>It is released in response to tissue injury and activates factor 10 in the extrinsic pathway.</p> Signup and view all the answers

What is the mnemonic device used to remember the intrinsic pathway factors?

<p>TENe10.</p> Signup and view all the answers

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