Platelet Function and Blood Coagulation

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What is the function of Gp2b/3a on the surface of platelets in the process of platelet aggregation?

It helps in the aggregation of platelets by forming a bond with fibrinogen.

What is the effect of flipping phosphatidylserine on the surface of platelets?

It gives a negative charge to platelets, leading to the activation of the clotting pathway.

What is the sequence of platelet aggregation?

Platelets with Gp2b/3a on their surface are attached by fibrinogen, leading to the aggregation of all platelets.

What is the mnemonic device used to remember the 'P' factors involved in platelet activation?

All P things and all Factors.

What is the role of tissue factor in the clotting pathway?

It is released in response to tissue injury and activates factor 10 in the extrinsic pathway.

What is the mnemonic device used to remember the intrinsic pathway factors?

TENe10.

This quiz covers the functions of platelets, including their contents, such as delta granules, and their role in platelet aggregation, blood coagulation, and the clotting cascade.

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