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Blood Coagulation Factors

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Questions and Answers

What is the primary cause of Hemophilia A?

Acquired deficiency of Factor IX

Vitamin C deficiency

Inherited deficiency of Factor VIII (correct)

Liver disease

Which of the following is an acquired factor deficiency?

Hemophilia B

Anticoagulant therapy (correct)

Myeloproliferative disorders

Von Willebrand's disease

What is the primary cause of Hemophilia B?

Liver disease

Acquired deficiency of Factor VIII

Inherited deficiency of Factor IX (correct)

Vitamin C deficiency

Which of the following is an inherited factor deficiency?

Von Willebrand's disease Signup and view all the answers

What is the primary cause of Von Willebrand's disease?

Inherited deficiency of Factor VIII-related antigen Signup and view all the answers

Which factor is most commonly affected in Von Willebrand's disease?

Factor VIII-related antigen Signup and view all the answers

What percentage of hemophiliacs have a deficiency of Factor VIII?

80-85% Signup and view all the answers

Which of the following laboratory tests is used to diagnose Von Willebrand's disease?

Prolonged BT and PTT Signup and view all the answers

What is the immediate effect of Coumadin anticoagulants?

It takes at least 48 to 72 hours for the anticoagulant effect to develop Signup and view all the answers

Which of the following is an acquired factor deficiency?

Anticoagulant therapy Signup and view all the answers

What is the role of Von Willebrand factor in circulation?

It binds to Factor VIII while it is inactive Signup and view all the answers

What is the primary mechanism of action of heparin in preventing blood clotting?

Activating antithrombin III to block thrombin Signup and view all the answers

What is the purpose of administering heparin concomitantly with Coumadin?

To provide an immediate anticoagulant effect Signup and view all the answers

In liver disease, which coagulation factors are reduced in production?

I, II, V, VII, IX, X Signup and view all the answers

What is the consequence of disseminated intravascular coagulation (DIC) on blood flow to organs?

Disrupted blood flow to organs, leading to organ malfunction Signup and view all the answers

What is the characteristic laboratory finding in disseminated intravascular coagulation (DIC)?

Prolonged PT and APTT, and reduced fibrinogen level Signup and view all the answers

What is the significance of high levels of fibrin degradation products, including D-dimer, in DIC?

It indicates the presence of intense fibrinolytic activity Signup and view all the answers

What is the advantage of using low molecular weight heparin over unfractionated heparin?

It has fewer side effects and more predictable plasma levels Signup and view all the answers

Blood Coagulation Factors

Choose a study mode

Podcast

Questions and Answers

What is the primary cause of Hemophilia A?

Which of the following is an acquired factor deficiency?

What is the primary cause of Hemophilia B?

Which of the following is an inherited factor deficiency?

What is the primary cause of Von Willebrand's disease?

Which factor is most commonly affected in Von Willebrand's disease?

What percentage of hemophiliacs have a deficiency of Factor VIII?

Which of the following laboratory tests is used to diagnose Von Willebrand's disease?

What is the immediate effect of Coumadin anticoagulants?

Which of the following is an acquired factor deficiency?

What is the role of Von Willebrand factor in circulation?

What is the primary mechanism of action of heparin in preventing blood clotting?

What is the purpose of administering heparin concomitantly with Coumadin?

In liver disease, which coagulation factors are reduced in production?

What is the consequence of disseminated intravascular coagulation (DIC) on blood flow to organs?

What is the characteristic laboratory finding in disseminated intravascular coagulation (DIC)?

What is the significance of high levels of fibrin degradation products, including D-dimer, in DIC?

What is the advantage of using low molecular weight heparin over unfractionated heparin?

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