Podcast
Questions and Answers
Which of the following is NOT a factor that limits clot formation in the coagulation process?
Which of the following is NOT a factor that limits clot formation in the coagulation process?
- Protein C
- Fibrinogen (correct)
- Thrombomodulin
- Antithrombin III
The extrinsic tenase complex is formed by the binding of:
The extrinsic tenase complex is formed by the binding of:
- Thrombin and fibrinogen
- Tissue factor and factor VIIa (correct)
- Factor IXa and factor VIIIa
- Factor Xa and factor Va
The intrinsic tenase complex is formed by the binding of:
The intrinsic tenase complex is formed by the binding of:
- Thrombin and fibrinogen
- Factor Xa and factor Va
- Factor IXa and factor VIIIa (correct)
- Tissue factor and factor VIIa
Which of the following is NOT a step in the coagulation cascade?
Which of the following is NOT a step in the coagulation cascade?
Which of the following statements about the regulation of haemostasis is TRUE?
Which of the following statements about the regulation of haemostasis is TRUE?
Which of the following is a key function of platelets in haemostasis?
Which of the following is a key function of platelets in haemostasis?
Which genetic mutation eliminates the cleavage site 506 and leads to activated Protein C resistance?
Which genetic mutation eliminates the cleavage site 506 and leads to activated Protein C resistance?
What is the predominant site of synthesis for Plasma Factor V?
What is the predominant site of synthesis for Plasma Factor V?
Which genetic mutation is associated with a 10-fold lower inactivation rate of Factor Va?
Which genetic mutation is associated with a 10-fold lower inactivation rate of Factor Va?
What is the impact of Factor V Leiden mutation on coagulation?
What is the impact of Factor V Leiden mutation on coagulation?
Which protein is predominantly synthesized in hepatocytes and stored in platelet alpha granules?
Which protein is predominantly synthesized in hepatocytes and stored in platelet alpha granules?
Which factor specifically inactivates both Factors Va and VIIIa in the coagulation cascade?
Which factor specifically inactivates both Factors Va and VIIIa in the coagulation cascade?
What is the function of Protein S in the clotting mechanism?
What is the function of Protein S in the clotting mechanism?
Which mutation leads to increased thrombotic risk in homozygotes?
Which mutation leads to increased thrombotic risk in homozygotes?
What is the normal plasma concentration of Factor V?
What is the normal plasma concentration of Factor V?
What does Thrombin specifically bind to on the surface of vascular endothelial cells?
What does Thrombin specifically bind to on the surface of vascular endothelial cells?
What is the primary function of the extrinsic tenase complex?
What is the primary function of the extrinsic tenase complex?
Which of the following is a natural inhibitor of the coagulation cascade?
Which of the following is a natural inhibitor of the coagulation cascade?
What is the primary function of the intrinsic tenase complex?
What is the primary function of the intrinsic tenase complex?
Which of the following is a vitamin K-dependent protein involved in the regulation of the coagulation cascade?
Which of the following is a vitamin K-dependent protein involved in the regulation of the coagulation cascade?
What is the primary function of Protein S in the regulation of the coagulation cascade?
What is the primary function of Protein S in the regulation of the coagulation cascade?
Which of the following is a serine protease inhibitor (SERPIN) involved in the regulation of the coagulation cascade?
Which of the following is a serine protease inhibitor (SERPIN) involved in the regulation of the coagulation cascade?
What is the primary function of the fibrinolytic system in the regulation of haemostasis?
What is the primary function of the fibrinolytic system in the regulation of haemostasis?
Which of the following is a cofactor for the activated Protein C (APC)-mediated inactivation of Factor Va and Factor VIIIa?
Which of the following is a cofactor for the activated Protein C (APC)-mediated inactivation of Factor Va and Factor VIIIa?
What is the primary function of the prothrombinase complex in the coagulation cascade?
What is the primary function of the prothrombinase complex in the coagulation cascade?
Which of the following is involved in the regulation of the fibrinolytic system?
Which of the following is involved in the regulation of the fibrinolytic system?
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