Blood and Circulation Overview
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Questions and Answers

What are the components of blood?

Blood is a special connective tissue consisting of a fluid matrix, plasma, and formed elements.

What is the role of plasma proteins?

Plasma proteins are involved in various functions, including defense mechanisms, osmotic balance, and clotting or coagulation of blood.

Which of the following is NOT a formed element of blood?

  • Leucocytes
  • Plasma (correct)
  • Platelets
  • Erythrocytes
  • What is the function of erythrocytes in blood?

    <p>Erythrocytes, also known as red blood cells, are responsible for the transport of respiratory gases, primarily oxygen, throughout the body.</p> Signup and view all the answers

    Which of the following is NOT a type of granulocyte?

    <p>Lymphocytes</p> Signup and view all the answers

    The process of blood clotting is also known as coagulation.

    <p>True</p> Signup and view all the answers

    What are the two major types of lymphocytes?

    <p>The two major types of lymphocytes are B lymphocytes and T lymphocytes, both playing crucial roles in the immune system.</p> Signup and view all the answers

    What is the function of platelets in blood?

    <p>Platelets are responsible for the coagulation or clotting of blood.</p> Signup and view all the answers

    What is the main difference between the ABO and Rh blood grouping systems?

    <p>The ABO blood grouping system is based on the presence or absence of antigens A and B on the surface of red blood cells, while the Rh blood grouping system is based on the presence or absence of the Rh antigen.</p> Signup and view all the answers

    What is the significance of the Rh factor in blood transfusions?

    <p>Rh incompatibility can lead to serious complications, particularly during pregnancy, as Rh-negative mothers producing antibodies against Rh-positive fetal blood can cause hemolytic disease of the newborn.</p> Signup and view all the answers

    What is lymph?

    <p>Lymph is a colorless fluid that circulates throughout the lymphatic system, collecting interstitial fluid and draining it back to the major veins.</p> Signup and view all the answers

    Which of the following is NOT a characteristic of the open circulatory system?

    <p>Heart pumps blood through a closed network of vessels</p> Signup and view all the answers

    Which of the following animals has a 4-chambered heart?

    <p>Bird</p> Signup and view all the answers

    What is the function of the human heart?

    <p>The human heart acts as a pump, circulating blood throughout the body, delivering oxygen and nutrients to tissues and removing waste products.</p> Signup and view all the answers

    What are the four chambers of the human heart?

    <p>The four chambers of the human heart are the right atrium, left atrium, right ventricle, and left ventricle.</p> Signup and view all the answers

    Describe the flow of blood through the heart during a single cardiac cycle.

    <p>The cardiac cycle involves the coordinated contraction and relaxation of the heart's chambers, resulting in the flow of blood from the atria to the ventricles and then to the pulmonary arteries and aorta.</p> Signup and view all the answers

    What is the role of the sino-atrial node (SAN) in the heart?

    <p>The SAN is the pacemaker of the heart, initiating and maintaining the rhythmic contractions of the heart.</p> Signup and view all the answers

    What is the difference between ventricular systole and ventricular diastole?

    <p>Ventricular systole is the contraction phase of the ventricles, pushing blood into the pulmonary artery and aorta, while ventricular diastole is the relaxation phase, allowing the ventricles to refill with blood.</p> Signup and view all the answers

    What is the purpose of the valves in the heart?

    <p>The valves in the heart prevent the backflow of blood, ensuring that blood flows in one direction, from the atria to the ventricles and then to the pulmonary artery and aorta.</p> Signup and view all the answers

    What is an electrocardiogram (ECG) and what does it show?

    <p>An ECG is a graphical representation of the electrical activity of the heart, showing the electrical impulses generated during each cardiac cycle.</p> Signup and view all the answers

    The pulmonary circulation involves the flow of oxygenated blood from the heart to the lungs.

    <p>False</p> Signup and view all the answers

    What is the difference between the pulmonary and systemic circulation?

    <p>The pulmonary circulation carries deoxygenated blood from the heart to the lungs for oxygenation, while the systemic circulation carries oxygenated blood from the heart to the rest of the body.</p> Signup and view all the answers

    What is the significance of double circulation in vertebrates?

    <p>Double circulation ensures that oxygenated and deoxygenated blood do not mix, leading to efficient oxygen delivery to the tissues and removing waste products.</p> Signup and view all the answers

    How is cardiac activity regulated?

    <p>Cardiac activity is regulated both intrinsically, by the autoregulation of the myogenic heart muscle, and extrinsically, by the autonomic nervous system.</p> Signup and view all the answers

    What are the main disorders associated with the circulatory system?

    <p>Major disorders of the circulatory system include hypertension, coronary artery disease (CAD), angina, and heart failure.</p> Signup and view all the answers

    What is the role of the hepatic portal system in the circulation of blood?

    <p>The hepatic portal system collects blood from the digestive tract and delivers it to the liver before it enters the systemic circulation.</p> Signup and view all the answers

    Study Notes

    Blood and Circulation

    • Blood is a special connective tissue with a fluid matrix (plasma) and formed elements.
    • Plasma (55% of blood) is a straw-colored, viscous fluid mainly composed of water (90-92%) and proteins (6-8%). Major proteins include fibrinogen, globulins, and albumins.
    • Formed elements (45% of blood) include erythrocytes (red blood cells), leucocytes (white blood cells), and platelets.

    Erythrocytes (Red Blood Cells)

    • Abundant cells in blood (5-5.5 million per mm³).
    • Biconcave disc shape, without a nucleus in mammals.
    • Contain hemoglobin, an iron-containing protein, which gives blood its color and facilitates oxygen transport.
    • Average lifespan of 120 days.
    • Destroyed in the spleen.

    Leucocytes (White Blood Cells)

    • Colorless due to lack of hemoglobin.
    • Nucleated cells.
    • Average count is 6000-8000 per mm³.
    • Types: Granulocytes (neutrophils, eosinophils, basophils) and agranulocytes (lymphocytes, monocytes).
    • Important in the body's defense mechanisms, particularly phagocytic cells like neutrophils and monocytes.

    Platelets

    • Cell fragments, also called thrombocytes.
    • Essential for blood clotting.
    • Produced in bone marrow.

    Blood Groups

    • ABO blood grouping is based on the presence or absence of antigens (A and B) on the RBCs and corresponding antibodies in the plasma.
    • Rh blood grouping is based on the presence or absence of Rh antigen on the RBCs.
    • Compatibility is crucial for blood transfusions.
    • O is universal donor.
    • AB is universal recipient.

    Lymph (Tissue Fluid)

    • Fluid released from capillaries into spaces between cells.
    • Contains minerals like plasma.
    • Important for exchange of nutrients and gases.
    • Lymphatic system collects this fluid and drains it back to the major veins carrying lymphocytes.

    Circulatory Pathways

    • Open circulatory systems in arthropods and mollusks. Blood pumped by the heart flows into open spaces (sinuses) in the body.
    • Closed circulatory systems in annelids and chordates. Blood is circulated through a closed system of blood vessels.
    • Fish have a two-chambered heart.
    • Amphibians and reptiles (except crocodiles) have a three-chambered heart.
    • Crocodiles, birds, and mammals have a four-chambered heart.
    • The heart in humans is a four-chambered muscular organ, protected by a double-walled pericardium.
    • Contains right and left atria, and right and left ventricles.
    • Heart valves (atrioventricular valves - tricuspid and bicuspid, semilunar) ensure unidirectional blood flow.
    • The heart's function is regulated by specialized cardiac muscle (nodal tissue - SAN and AVN).

    Cardiac Cycle

    • Sequence of events that occur during one complete heartbeat.
    • Systole - contraction phase.
    • Diastole - relaxation phase.
    • Cardiac output - amount of blood pumped by each ventricle per minute.
    • Stroke volume - amount of blood pumped out by each ventricle with each heartbeat.
    • Pulse rate - measures the number of heartbeats per minute.

    Regulation of Cardiac Activity

    • Intrinsic regulation (myogenic).
    • Extrinsic regulation by nerves and hormones.

    Disorders of the Circulatory System

    • Hypertension (high blood pressure)
    • Coronary artery disease (narrowing of coronary vessels)
    • Angina (chest pain).
    • Heart failure (inadequate pumping of blood).

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    Description

    This quiz covers the essential components of blood and circulation, focusing on the functions and characteristics of blood plasma and formed elements. It provides key insights into erythrocytes and leucocytes, their roles, structure, and lifespan. Perfect for students learning about human physiology.

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