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What is the brand name for bismuth subsalicylate?
What is the brand name for bismuth subsalicylate?
What are the drug classes for bismuth subsalicylate?
What are the drug classes for bismuth subsalicylate?
What are the indications for bismuth subsalicylate?
What are the indications for bismuth subsalicylate?
Diarrhea, heartburn, nausea
What are the dosage forms for bismuth subsalicylate?
What are the dosage forms for bismuth subsalicylate?
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What is the dosing for bismuth subsalicylate?
What is the dosing for bismuth subsalicylate?
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Is renal dosing adjustment necessary for bismuth subsalicylate?
Is renal dosing adjustment necessary for bismuth subsalicylate?
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What are the contraindications for bismuth subsalicylate?
What are the contraindications for bismuth subsalicylate?
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What are common adverse drug reactions (ADRs) for bismuth subsalicylate?
What are common adverse drug reactions (ADRs) for bismuth subsalicylate?
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What are serious adverse drug reactions (ADRs) for bismuth subsalicylate?
What are serious adverse drug reactions (ADRs) for bismuth subsalicylate?
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What are the monitoring parameters for bismuth subsalicylate?
What are the monitoring parameters for bismuth subsalicylate?
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What drug interactions are associated with bismuth subsalicylate?
What drug interactions are associated with bismuth subsalicylate?
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What are the counseling points for bismuth subsalicylate?
What are the counseling points for bismuth subsalicylate?
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Study Notes
Bismuth Subsalicylate Overview
- Brand names include Pepto Bismol and Kaopectate.
- Classified as both an antidiarrheal and an antacid.
Indications
- Effective for treating diarrhea.
- Alleviates heartburn symptoms.
- Used to manage nausea.
Dosage Forms
- Available as an oral suspension.
- Also comes in chewable tablet form.
Dosing Guidelines
- Typical dosing is 525 mg every 30 to 60 minutes as needed.
- Maximum dosage is capped at 8 doses per day.
Renal Considerations
- No renal dosing adjustments are necessary.
Contraindications
- Should not be used if there is a presence of gastrointestinal (GI) bleeding.
- Active ulcers are a contraindication.
- Avoid use if blood or black stools are present.
Common Adverse Drug Reactions (ADRs)
- Can cause constipation and discoloration of the tongue.
- May lead to grayish-black stools.
- Other potential side effects include anxiety, confusion, headache, mental depression, slurred speech, muscle spasms, weakness, and tinnitus.
Serious Adverse Drug Reactions
- Risk of anaphylaxis, which is a severe allergic reaction.
- Potential for encephalopathy, leading to brain dysfunction.
- Neurotoxicity can occur with significant adverse effects on the nervous system.
Monitoring Parameters
- Monitor for relief of diarrhea or heartburn symptoms.
- Watch for signs of constipation or abdominal pain; severe symptoms warrant medical attention.
Drug Interactions
- May interact with tetracycline antibiotics, which can affect their effectiveness.
Counseling Points
- For mild, uncomplicated diarrhea, oral rehydration therapy should accompany bismuth subsalicylate treatment.
- Shake the suspension before each use and utilize the measuring device included in the packaging.
- Tablets should be consumed with 120-240 mL of water, either chewed or dissolved in the mouth.
- Users may experience tongue or stool discoloration; this is typically benign but should be noted.
- Inform a healthcare professional immediately if tinnitus develops.
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Test your knowledge of bismuth subsalicylate with these flashcards. This quiz covers brand names, drug class, indications, and dosage forms. Perfect for pharmacy students or anyone interested in pharmacology.