Bismuth Subsalicylate Flashcards

Questions and Answers

What is the brand name for bismuth subsalicylate?

Pepto Bismol (correct)

Kaopectate (correct)

Tums

Imodium

What are the drug classes for bismuth subsalicylate?

Antidiarrheal (correct)

Antibiotic

Antacid (correct)

Analgesic

What are the indications for bismuth subsalicylate?

Diarrhea, heartburn, nausea

What are the dosage forms for bismuth subsalicylate?

Oral suspension, chewable tablet Signup and view all the answers

What is the dosing for bismuth subsalicylate?

525 mg q 30-60 min prn, MAX: 8 doses/day Signup and view all the answers

Is renal dosing adjustment necessary for bismuth subsalicylate?

False Signup and view all the answers

What are the contraindications for bismuth subsalicylate?

Presence of GI bleeding, active ulcer, blood/black stool Signup and view all the answers

What are common adverse drug reactions (ADRs) for bismuth subsalicylate?

Constipation, discoloration of the tongue, grayish black stools, anxiety, confusion, headache, mental depression, slurred speech, muscle spasms, weakness, hearing loss, tinnitus Signup and view all the answers

What are serious adverse drug reactions (ADRs) for bismuth subsalicylate?

Anaphylaxis, encephalopathy, neurotoxicity Signup and view all the answers

What are the monitoring parameters for bismuth subsalicylate?

Relief from diarrhea or heartburn; seek medical attention for severe constipation or abdominal pain. Signup and view all the answers

What drug interactions are associated with bismuth subsalicylate?

Tetracycline antibiotics Signup and view all the answers

What are the counseling points for bismuth subsalicylate?

Oral rehydration therapy for mild, uncomplicated diarrhea must accompany treatment; shake suspension before use; take tablets with water; may experience tongue or stool discoloration; inform HCP if tinnitus occurs. Signup and view all the answers

Study Notes

Bismuth Subsalicylate Overview

Brand names include Pepto Bismol and Kaopectate.
Classified as both an antidiarrheal and an antacid.

Indications

Effective for treating diarrhea.
Alleviates heartburn symptoms.
Used to manage nausea.

Dosage Forms

Available as an oral suspension.
Also comes in chewable tablet form.

Dosing Guidelines

Typical dosing is 525 mg every 30 to 60 minutes as needed.
Maximum dosage is capped at 8 doses per day.

Renal Considerations

No renal dosing adjustments are necessary.

Contraindications

Should not be used if there is a presence of gastrointestinal (GI) bleeding.
Active ulcers are a contraindication.
Avoid use if blood or black stools are present.

Common Adverse Drug Reactions (ADRs)

Can cause constipation and discoloration of the tongue.
May lead to grayish-black stools.
Other potential side effects include anxiety, confusion, headache, mental depression, slurred speech, muscle spasms, weakness, and tinnitus.

Serious Adverse Drug Reactions

Risk of anaphylaxis, which is a severe allergic reaction.
Potential for encephalopathy, leading to brain dysfunction.
Neurotoxicity can occur with significant adverse effects on the nervous system.

Monitoring Parameters

Monitor for relief of diarrhea or heartburn symptoms.
Watch for signs of constipation or abdominal pain; severe symptoms warrant medical attention.

Drug Interactions

May interact with tetracycline antibiotics, which can affect their effectiveness.

Counseling Points

For mild, uncomplicated diarrhea, oral rehydration therapy should accompany bismuth subsalicylate treatment.
Shake the suspension before each use and utilize the measuring device included in the packaging.
Tablets should be consumed with 120-240 mL of water, either chewed or dissolved in the mouth.
Users may experience tongue or stool discoloration; this is typically benign but should be noted.
Inform a healthcare professional immediately if tinnitus develops.

Description

Test your knowledge of bismuth subsalicylate with these flashcards. This quiz covers brand names, drug class, indications, and dosage forms. Perfect for pharmacy students or anyone interested in pharmacology.