Bipolar Disorder: Understanding Mood Swings
32 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the typical duration of symptoms required for a diagnosis of mania according to the ICD10 classification?

  • At least one week (correct)
  • At least four weeks
  • At least 24 hours
  • At least two weeks
  • Which neurotransmitter is NOT associated with the monamine theory of mania?

  • GABA
  • Serotonin
  • Dopamine
  • Acetylcholine (correct)
  • What is the typical consequence of treating underlying metabolic disorders that cause manic symptoms?

  • Resolution of symptoms within a month
  • Resolution of symptoms within a week (correct)
  • No resolution of symptoms
  • Resolution of symptoms within three months
  • What is the primary risk associated with not treating hypomania promptly?

    <p>Risk of physical exhaustion</p> Signup and view all the answers

    What is the typical course of bipolar disorder?

    <p>Chronic and recurrent</p> Signup and view all the answers

    What is the primary goal of treating acute hypomania?

    <p>To prevent physical exhaustion</p> Signup and view all the answers

    What is the primary characteristic of bipolar disorder?

    <p>Distinct periods of mania or hypomania accompanied by periods of depression</p> Signup and view all the answers

    What is the primary difference between bipolar I and bipolar II?

    <p>Presence or absence of full-blown manic episodes</p> Signup and view all the answers

    What is the genetic predisposition of bipolar disorder?

    <p>Approximately 65% of sufferers have a family member with BPD</p> Signup and view all the answers

    What is the role of cortisol in the etiology of bipolar disorder?

    <p>Cortisol has a negative feedback on the hypothalamus, reducing CRH release</p> Signup and view all the answers

    What is a common symptom of the manic phase of bipolar disorder?

    <p>Reduced need for sleep</p> Signup and view all the answers

    What is a possible underlying cause of bipolar disorder?

    <p>Neurohormonal abnormalities, specifically HPA axis dysfunction</p> Signup and view all the answers

    What is the primary concern when using antidepressants in patients with bipolar disorder?

    <p>Risk of inducing more switching to mania</p> Signup and view all the answers

    Which of the following medications is NOT a mood stabilizer?

    <p>Haloperidol</p> Signup and view all the answers

    What is the mechanism of action of lithium on second messenger systems?

    <p>Inhibits G-proteins</p> Signup and view all the answers

    What is the therapeutic range of lithium in terms of plasma levels?

    <p>0.4 to 1.0 mmol/l</p> Signup and view all the answers

    What is the recommended frequency of blood testing for lithium levels after achieving a stable therapeutic range?

    <p>Every 3-6 months</p> Signup and view all the answers

    What is a common side effect of lithium therapy?

    <p>Fine hand tremor</p> Signup and view all the answers

    What is a sign of lithium toxicity?

    <p>Blurred vision</p> Signup and view all the answers

    What is the primary mechanism of lithium clearance?

    <p>Renal excretion</p> Signup and view all the answers

    What is the effect of NSAIDs on lithium levels?

    <p>Increases lithium levels</p> Signup and view all the answers

    What is the ideal dose of lithium in terms of mEq/l?

    <p>0.6-0.8 mEq/l</p> Signup and view all the answers

    What is the effect of candesartan/irbesartan on lithium levels?

    <p>Decreases renal clearance</p> Signup and view all the answers

    Which of the following antidepressants are associated with hyponatremia?

    <p>SSRIs and Li+</p> Signup and view all the answers

    What is the mechanism of action of valproic acid?

    <p>Enhances GABA neurotransmission</p> Signup and view all the answers

    What is the CSM warning regarding valproic acid?

    <p>Women of childbearing age</p> Signup and view all the answers

    What is the effect of carbamazepine on NA release?

    <p>Decreases NA release</p> Signup and view all the answers

    Why is lamotrigine particularly useful in bipolar disorder?

    <p>It avoids the need for antidepressants</p> Signup and view all the answers

    What is a particular challenge in managing bipolar disorder?

    <p>Long term compliance is typically low</p> Signup and view all the answers

    What is a risk of using antidepressants in bipolar disorder?

    <p>Risk of switching into mania</p> Signup and view all the answers

    What is a concern in managing bipolar illness in women of child-bearing age?

    <p>Risk of relapse is high</p> Signup and view all the answers

    What is an association of valproate?

    <p>Increased risk of polycystic ovary disease</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Browser