Questions and Answers
What is the process by which a drug is chemically converted in the body?
Which component of drug elimination involves the chemical conversion of the drug?
What is the usual process by which drug action is terminated?
Which phase of drug metabolism involves the preparation of foreign chemicals for removal from the body?
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What is the process by which metabolites contribute to hepatotoxicity, nephrotoxicity, teratogenecity, and carcinogeneticity?
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What is the process of preparing foreign chemicals for removal from the body?
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Which component of drug elimination involves chemical conversion of the drug?
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What is the usual process by which drug action is terminated?
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In which phase of drug metabolism are metabolites contributing to hepatotoxicity, nephrotoxicity, teratogenecity, and carcinogeneticity?
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What is the process by which drug action is terminated?
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Study Notes
Drug Metabolism
- The process by which a drug is chemically converted in the body is called biotransformation.
- The component of drug elimination that involves the chemical conversion of the drug is biotransformation.
- The usual process by which drug action is terminated is through biotransformation, which converts the active drug into inactive metabolites.
Phases of Drug Metabolism
- The phase of drug metabolism that involves the preparation of foreign chemicals for removal from the body is Phase II.
- Phase I of drug metabolism involves the introduction of a functional group, making the drug more hydrophilic.
Metabolites and Toxicity
- The process by which metabolites contribute to hepatotoxicity, nephrotoxicity, teratogenecity, and carcinogeneticity is through their reactive properties, which can cause cellular damage.
- The process of preparing foreign chemicals for removal from the body is called biotransformation, which involves both Phase I and Phase II reactions.
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Description
Test your knowledge of biotransformation with this quiz! Learn about drug metabolism and how it can alter the properties of drugs. Explore the principle sites of drug metabolism and understand the impact of metabolites on toxicity. Sharpen your understanding of pharmacology and toxicology with this informative quiz.
