Biotransformation Quiz

Drug Metabolism

• The process by which a drug is chemically converted in the body is called biotransformation.
• The component of drug elimination that involves the chemical conversion of the drug is biotransformation.
• The usual process by which drug action is terminated is through biotransformation, which converts the active drug into inactive metabolites.

Phases of Drug Metabolism

• The phase of drug metabolism that involves the preparation of foreign chemicals for removal from the body is Phase II.
• Phase I of drug metabolism involves the introduction of a functional group, making the drug more hydrophilic.

Metabolites and Toxicity

• The process by which metabolites contribute to hepatotoxicity, nephrotoxicity, teratogenecity, and carcinogeneticity is through their reactive properties, which can cause cellular damage.
• The process of preparing foreign chemicals for removal from the body is called biotransformation, which involves both Phase I and Phase II reactions.