5 Questions
What is the main purpose of biotransformation in the body?
To convert drugs into more polar, water-soluble compounds for easier excretion
What is the consequence of biotransformation for some drugs?
It converts the drug to an active metabolite
Where is the most important organ of biotransformation located?
Liver
In which part of the cell are microsomal enzymes located for biotransformation reactions?
Endoplasmic reticulum
What is the main function of non-microsome enzymes in biotransformation?
To activate prodrugs
Test your understanding of biotransformation, the process of biochemical alteration of drugs in the body, and how it affects drug excretion and metabolism in different organs. Explore the site of metabolism and the consequences of biotransformation on drug efficacy and toxicity.
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