Podcast
Questions and Answers
What is a highly preferred feed for horses?
What is a highly preferred feed for horses?
Oats
Which of the following are benefits of feeding oats to horses? (Select all that apply)
Which of the following are benefits of feeding oats to horses? (Select all that apply)
Oats can lead to digestive disorders in horses.
Oats can lead to digestive disorders in horses.
False
What two pathways are involved in the biosynthesis of nucleotides?
What two pathways are involved in the biosynthesis of nucleotides?
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Purine ring is synthesized by a series of _____ reactions.
Purine ring is synthesized by a series of _____ reactions.
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Which of the following statements are true regarding pyrimidine synthesis? (Select all that apply)
Which of the following statements are true regarding pyrimidine synthesis? (Select all that apply)
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What enzymes are involved in the purine salvage pathway?
What enzymes are involved in the purine salvage pathway?
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What are some symptoms of Lesch-Nyhan syndrome?
What are some symptoms of Lesch-Nyhan syndrome?
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Study Notes
Oats for Horses
- Oats are a popular feed for horses due to their nutritious profile.
- They provide high energy, balanced protein, and various amino acids.
- Oats are high in fiber which promotes digestion and reduces digestive disorders.
- Feeding oats raw simplifies preparation and helps maintain a stable gut microbiome.
Biosynthesis of Nucleotides
- Nucleotides can be synthesized through two pathways: de novo and salvage.
- The de novo pathway synthesizes nucleotides from scratch using precursor molecules.
- Purines are synthesized in segments directly onto the ribose structure.
- Pyrimidines are synthesized first and then assembled onto the ribose structure.
- The salvage pathway reuses existing metabolites for nucleotide biosynthesis.
De Novo Purine Synthesis
- The purine ring is synthesized through 12 reactions.
- Carbon and nitrogen atoms are added to a pre-formed ribose-5-phosphate.
- Ribose-5-phosphate is produced from the Hexose MonoPhosphate Pathway.
De Novo Pyrimidine Synthesis
- The pyrimidine ring is synthesized first and then attached to a ribose-5-phosphate donated by PRPP.
- The sources of carbons and nitrogens are less diverse in pyrimidine synthesis compared to purine synthesis.
Purine Salvage Pathway
- Reutilizes adenine, hypoxanthine, and guanine.
- Two enzymes are involved: adenine phosphoribosyltransferase and hypoxanthine-guanine phosphoribosyltransferase.
Lesch-Nyhan Syndrome
- This syndrome involves impaired kidney function, acute gouty arthritis, and self-mutilating behaviors.
- Additional symptoms include involuntary muscle movements and neurological impairment.
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Description
This quiz covers two distinct topics: the nutritional benefits of oats as horse feed and the intricate biosynthesis of nucleotides. Learn how oats contribute to equine health and delve into the pathways of de novo and salvage nucleotide synthesis. Perfect for students in veterinary science and biochemistry!
