Biomolecules and Central Dogma Quiz

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Questions and Answers

What is the significance of the 5' carbon in pentose sugar during DNA replication?

  • It helps differentiate between ribose and deoxyribose.
  • It is where the phosphate group attaches to the sugar. (correct)
  • It signals the end of the DNA strand.
  • It indicates where the nitrogenous base attaches.

Which structure characterizes RNA compared to DNA?

  • Double-stranded helical structure.
  • Has the same sugar as DNA.
  • Single strand of nucleotides. (correct)
  • Contains thymine as a nitrogenous base.

In the context of DNA replication, what does semiconservative replication mean?

  • Both strands of the original DNA remain with each other.
  • Each new DNA molecule contains one old strand and one newly synthesized strand. (correct)
  • DNA is completely fragmented before replication.
  • Only one new strand is formed from each original strand.

What informational role does RNA serve in the cell?

<p>It delivers instructions from DNA to produce proteins. (B)</p> Signup and view all the answers

Which base pairing occurs between the nitrogenous bases in RNA?

<p>G pairs with C and A pairs with U. (D)</p> Signup and view all the answers

Which of the following biomolecules is primarily responsible for providing stored energy reserves?

<p>Lipids (C)</p> Signup and view all the answers

What type of reaction occurs when two monomers combine to form a dimer?

<p>Dehydration (C)</p> Signup and view all the answers

Which bond is formed between monosaccharides in carbohydrates?

<p>Glycosidic bond (A)</p> Signup and view all the answers

What is the role of proteins in the body?

<p>To form new bones and muscles (A)</p> Signup and view all the answers

Which of the following statements about nucleic acids is true?

<p>They are the blueprint for genetic structure. (B)</p> Signup and view all the answers

What is the primary structural component that constitutes proteins?

<p>Amino Acids (A)</p> Signup and view all the answers

Which statement correctly differentiates lipids from the other biomolecules?

<p>Lipids do not have monomers. (B)</p> Signup and view all the answers

What process reverses a dehydration reaction to break down polymers?

<p>Hydrolysis (C)</p> Signup and view all the answers

Which of the following statements about monosaccharides is NOT true?

<p>They are typically composed of 5-10 carbon atoms. (D)</p> Signup and view all the answers

What distinguishes unsaturated lipids from saturated lipids?

<p>Unsaturated lipids have at least one double bond between carbon atoms. (B)</p> Signup and view all the answers

Which of the following best describes the structure of phospholipids?

<p>They have a polar phosphate group and two fatty acid chains. (C)</p> Signup and view all the answers

Which statement about the functions of carbohydrates is accurate?

<p>Carbohydrates play a structural role in the cell wall of plants. (B)</p> Signup and view all the answers

What is a key characteristic of saturated lipids?

<p>They contribute to high blood pressure when consumed excessively. (C)</p> Signup and view all the answers

Which of the following is NOT a function of proteins?

<p>Serves as long-term energy storage. (C)</p> Signup and view all the answers

What is the building block of carbohydrates?

<p>Monosaccharides (A)</p> Signup and view all the answers

Which of the following biopolymers is formed by condensation reactions of monosaccharides?

<p>Polysaccharides (B)</p> Signup and view all the answers

What defines the primary structure of a protein?

<p>The linear sequence of amino acids linked by peptide bonds (D)</p> Signup and view all the answers

Which of the following correctly identifies a component of a nucleotide?

<p>Nitrogenous base (B)</p> Signup and view all the answers

What distinguishes RNA from DNA at the second carbon of the sugar component?

<p>RNA contains a hydroxyl group, DNA contains a hydrogen atom (B)</p> Signup and view all the answers

What is the significance of Chargaff's rules in DNA structure?

<p>They indicate relative amounts of nucleotides in DNA (A)</p> Signup and view all the answers

Which structure is associated with the tertiary level of protein folding?

<p>The overall three-dimensional shape of a single polypeptide (C)</p> Signup and view all the answers

Which of the following correctly describes the pairing of nucleotides in DNA?

<p>Adenine pairs with Thymine and Guanine pairs with Cytosine (D)</p> Signup and view all the answers

What element is NOT a component of nucleic acids?

<p>Iron (A)</p> Signup and view all the answers

Which of the following is true regarding the structure of DNA proposed by Watson and Crick?

<p>DNA consists of a double helix with a sugar-phosphate backbone (A)</p> Signup and view all the answers

Flashcards

Biomolecules

Molecules found naturally in living organisms, often obtained from food, and crucial for maintenance and metabolic processes.

Carbon

The most versatile element in life's functions, found in all biomolecules.

Macromolecules

Large molecules consisting of thousands of covalently linked atoms. Examples include carbohydrates, proteins, and nucleic acids.

Dehydration Reaction

A process where two monomers join together, releasing a water molecule.

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Hydrolysis

A process where polymers are broken down into monomers by adding a water molecule.

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Monomers

The basic building blocks of polymers. These smaller units join together to form larger chains.

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Polymerization

The process of joining monomers together to form a polymer chain. It involves the removal of a water molecule.

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Central Dogma

The central dogma of molecular biology explains the flow of genetic information from: DNA to RNA to Protein.

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What are Carbohydrates?

Carbohydrates are large molecules composed of carbon, hydrogen, and oxygen in a 1:2:1 ratio, forming long chains of sugar units.

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What are Monosaccharides?

Monosaccharides are the simplest form of carbohydrates, containing 3-7 carbon atoms and acting as reducing sugars.

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What are Polysaccharides?

Polysaccharides are complex carbohydrates formed by linking many monosaccharide units together. They serve as energy storage and structural components.

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What are Oligosaccharides?

Oligosaccharides are carbohydrates composed of 2-9 monosaccharide units linked by glycosidic bonds. They include disaccharides, trisaccharides, and tetrasaccharides.

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What are Lipids?

Lipids are hydrophobic molecules, meaning they don't dissolve in water. They are mainly composed of carbon and hydrogen atoms, with some oxygen.

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What are Saturated Lipids?

Saturated lipids have all single bonds between carbon atoms, making them solid at room temperature. Excess saturated fats can clog arteries.

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What are Unsaturated Lipids?

Unsaturated lipids have at least one double bond between carbon atoms, making them liquid at room temperature. They are generally considered healthier than saturated fats.

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What are Proteins?

Proteins are large, complex molecules made of amino acids linked together by peptide bonds. They are crucial for many biological functions.

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What are phosphodiester bonds?

The covalent bond that links nucleotides together in a DNA or RNA strand. Involves a 5' phosphate group of one nucleotide bonding to the 3' hydroxyl group of the next nucleotide.

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What is Semiconservative Replication?

The process of creating a new strand of DNA from a template strand using complementary base pairing. Ensures each new DNA molecule has one original and one newly synthesized strand.

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What is Transcription?

The process where DNA is copied to produce RNA. This plays a key role in protein synthesis as it carries the instructions from DNA to ribosomes.

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What is the unique base pairing in RNA?

In RNA, the nitrogenous base Adenine pairs with Uracil, not Thymine.

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What is the difference in sugars in RNA and DNA?

The sugar in RNA is ribose, which has an extra hydroxyl group compared to deoxyribose, the sugar in DNA.

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Primary Structure of Proteins

The linear sequence of amino acids linked together by peptide bonds.

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Secondary Structure of Proteins

Polypeptide folding into an alpha helix or beta sheet arrangement.

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Tertiary Structure of Proteins

The three-dimensional folding of a single polypeptide chain.

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Quaternary Structure of Proteins

Association of two or more folded polypeptides to form a multi-meric protein.

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Nucleotide

The building blocks of nucleic acids, consisting of a nitrogenous base, a pentose sugar, and a phosphate group.

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DNA Structure

A double helix structure made up of a sugar-phosphate backbone on the outside and bases on the inside. This structure is crucial for storing and transmitting genetic information.

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Base Pairing Rules

The process of how nucleotides pair up in DNA: Adenine (A) pairs with Thymine (T), and Guanine (G) pairs with Cytosine (C).

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Chargaff's Rule

The amount of adenine (A) is equal to the amount of thymine (T) in the DNA of a cell, and the amount of guanine (G) is equal to the amount of cytosine (C).

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Study Notes

Biomolecules and the Central Dogma of Life

  • Biomolecules are naturally occurring molecules in organisms, including carbohydrates, lipids, proteins, and nucleic acids
  • These molecules play roles in maintenance and metabolic processes.
  • Biomolecules are usually obtained from food
  • Carbon is the most versatile element, found in all biomolecules.
  • Other elements include Hydrogen, Oxygen, Nitrogen, Sulfur, Sodium, Calcium, and Magnesium
  • Atoms combine to form larger molecules: atoms --> molecules --> macromolecules
  • Macromolecules are very large molecules made up of thousands of atoms connected covalently.

Functions of Biomolecules

  • Carbohydrates are the body's main source of energy.
  • Lipids provide stored energy reserves when carbohydrates are unavailable.
  • Proteins help in building bones, muscles, and fight diseases.
  • Nucleic acids are involved in storing and transmitting genetic information, controlling cell processes.

Breaking of Macromolecules

  • Macromolecules can be broken down (hydrolyzed) to monomers (smaller units).
  • Polymers are formed by joining monomers.
  • Monomers, such as glucose, are building blocks for other larger molecules.

Types of Macromolecules

  • Carbohydrates: Made of monosaccharides (e.g., glucose, fructose).
  • Proteins: Made of amino acids (e.g., Alanine, glycine).
  • Nucleic acids: Made of nucleotides (e.g., adenine, guanine).
  • Lipids: Made of fatty acids.

Lipids

  • Lipids are hydrophobic (water-repelling).
  • Lipids are important for energy storage, cell structure (phospholipids), and hormones (steroids).

Proteins

  • Proteins are polymers of amino acids.
  • They have complex structures (primary, secondary, tertiary, and quaternary) which determine their function.
  • Function as enzymes, hormones, structural components, and more.

Nucleic Acids (DNA and RNA)

  • Nucleic acids are polymers of nucleotides.
  • DNA stores genetic information.
  • RNA plays roles in protein synthesis and other cellular processes.
  • Nucleotides have a nitrogenous base, a pentose sugar (deoxyribose or ribose), and a phosphate group.

Central Dogma of Molecular Biology

  • Information flows from DNA to RNA to protein.
  • Transcription is the process of copying DNA into RNA.
  • Translation is the process of decoding RNA into a protein.
  • Replication is the process of making copies of DNA.

DNA Replication

  • DNA replication is semi-conservative.
  • Each new DNA molecule consists of one original strand and one newly synthesized strand.

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