Biology of Lymphomatous Transformation Quiz
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Questions and Answers

Where does somatic switching occur for oncogenes?

  • Bone marrow
  • Marrow
  • T lymphocytes
  • Germinal center (correct)
  • Which surface markers confirm the hematopoietic nature of tumors?

  • CD16
  • CD2
  • CD3
  • CD45 (correct)
  • Which cells express IgM/IgD in the early stage of B-lymphocyte development?

  • Memory cells
  • T lymphocytes
  • Plasma cells
  • Cells in bone marrow (correct)
  • What triggers B cells, leading to translocation of oncogenes?

    <p>Somatic hypermutation failure</p> Signup and view all the answers

    Which TCR genes do mature T-cells express?

    <p>α,β,γ,δ</p> Signup and view all the answers

    What is the surface Ig receptor that performs antigen-derived activation signaling?

    <p>CD79a and CD79b</p> Signup and view all the answers

    Which cells express IgG, IgA, or IgM in the late stage of B-lymphocyte development?

    <p>Cells in germinal centers</p> Signup and view all the answers

    Which markers are expressed on T lymphocytes?

    <p>CD4, CD8</p> Signup and view all the answers

    Which markers are expressed on NK/Cytotoxic T cells?

    <p>CD16, CD56, CD57</p> Signup and view all the answers

    Which cells express the goal of antibodies in the late stage of B-lymphocyte development?

    <p>Plasma cells or Memory Cells</p> Signup and view all the answers

    Which surface markers are expressed on NK/Cytotoxic T cells?

    <p>CD16, CD56, CD57</p> Signup and view all the answers

    Which cells express IgG, IgA, or IgM in the late stage of B-lymphocyte development?

    <p>Plasma cells or Memory Cells</p> Signup and view all the answers

    Where does somatic switching occur for oncogenes?

    <p>Germinal center</p> Signup and view all the answers

    Which TCR genes do mature T-cells express?

    <p>α,β,γ,δ</p> Signup and view all the answers

    What triggers B cells, leading to translocation of oncogenes?

    <p>Somatic hypermutation failure</p> Signup and view all the answers

    Which surface markers confirm the hematopoietic nature of tumors?

    <p>CD45</p> Signup and view all the answers

    Which cells express IgM/IgD in the early stage of B-lymphocyte development?

    <p>Cells in bone marrow</p> Signup and view all the answers

    Which markers are expressed on T lymphocytes?

    <p>CD2, CD3, CD4, CD5, CD7, CD8, CD25</p> Signup and view all the answers

    What is the surface Ig receptor that performs antigen-derived activation signaling?

    <p>CD79a and CD79b</p> Signup and view all the answers

    Which cells express the goal of antibodies in the late stage of B-lymphocyte development?

    <p>Plasma cells or Memory Cells</p> Signup and view all the answers

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