Biology of Lymphomatous Transformation Quiz
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Questions and Answers

Where does somatic switching occur for oncogenes?

  • Bone marrow
  • Marrow
  • T lymphocytes
  • Germinal center (correct)

Which surface markers confirm the hematopoietic nature of tumors?

  • CD16
  • CD2
  • CD3
  • CD45 (correct)

Which cells express IgM/IgD in the early stage of B-lymphocyte development?

  • Memory cells
  • T lymphocytes
  • Plasma cells
  • Cells in bone marrow (correct)

What triggers B cells, leading to translocation of oncogenes?

<p>Somatic hypermutation failure (D)</p> Signup and view all the answers

Which TCR genes do mature T-cells express?

<p>α,β,γ,δ (B)</p> Signup and view all the answers

What is the surface Ig receptor that performs antigen-derived activation signaling?

<p>CD79a and CD79b (C)</p> Signup and view all the answers

Which cells express IgG, IgA, or IgM in the late stage of B-lymphocyte development?

<p>Cells in germinal centers (B)</p> Signup and view all the answers

Which markers are expressed on T lymphocytes?

<p>CD4, CD8 (D)</p> Signup and view all the answers

Which markers are expressed on NK/Cytotoxic T cells?

<p>CD16, CD56, CD57 (B)</p> Signup and view all the answers

Which cells express the goal of antibodies in the late stage of B-lymphocyte development?

<p>Plasma cells or Memory Cells (A)</p> Signup and view all the answers

Which surface markers are expressed on NK/Cytotoxic T cells?

<p>CD16, CD56, CD57 (D)</p> Signup and view all the answers

Which cells express IgG, IgA, or IgM in the late stage of B-lymphocyte development?

<p>Plasma cells or Memory Cells (B)</p> Signup and view all the answers

Where does somatic switching occur for oncogenes?

<p>Germinal center (C)</p> Signup and view all the answers

Which TCR genes do mature T-cells express?

<p>α,β,γ,δ (B)</p> Signup and view all the answers

What triggers B cells, leading to translocation of oncogenes?

<p>Somatic hypermutation failure (B)</p> Signup and view all the answers

Which surface markers confirm the hematopoietic nature of tumors?

<p>CD45 (D)</p> Signup and view all the answers

Which cells express IgM/IgD in the early stage of B-lymphocyte development?

<p>Cells in bone marrow (A)</p> Signup and view all the answers

Which markers are expressed on T lymphocytes?

<p>CD2, CD3, CD4, CD5, CD7, CD8, CD25 (A)</p> Signup and view all the answers

What is the surface Ig receptor that performs antigen-derived activation signaling?

<p>CD79a and CD79b (C)</p> Signup and view all the answers

Which cells express the goal of antibodies in the late stage of B-lymphocyte development?

<p>Plasma cells or Memory Cells (A)</p> Signup and view all the answers

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