Podcast
Questions and Answers
Which of the following statements accurately describes saltatory conduction?
Which of the following statements accurately describes saltatory conduction?
- The action potential is generated at the axon terminal and travels back towards the trigger zone.
- The action potential 'jumps' from one node of Ranvier to the next due to the insulating effect of the myelin sheath. (correct)
- The action potential travels continuously down the axon without any breaks.
- The action potential travels slower in myelinated axons compared to unmyelinated axons.
What is the primary factor that determines the speed of action potential propagation?
What is the primary factor that determines the speed of action potential propagation?
- The length of the axon.
- The diameter of the axon and whether it is myelinated or not. (correct)
- The concentration of potassium ions in the extracellular fluid.
- The type of neurotransmitter released at the synapse.
How does myelination affect the speed of action potential conduction?
How does myelination affect the speed of action potential conduction?
- Myelination slows down conduction by creating a barrier to ion flow.
- Myelination decreases conduction speed by reducing the number of voltage-gated sodium channels.
- Myelination has no significant effect on conduction speed.
- Myelination increases conduction speed by allowing the action potential to 'jump' from node to node. (correct)
Which of the following is NOT a characteristic of myelinated axons?
Which of the following is NOT a characteristic of myelinated axons?
What happens to the amplitude of the action potential as it travels down a myelinated axon?
What happens to the amplitude of the action potential as it travels down a myelinated axon?
Which of the following statements correctly describes the relationship between axon diameter and conduction velocity?
Which of the following statements correctly describes the relationship between axon diameter and conduction velocity?
What is the difference between the speed of action potential conduction in a myelinated 8.6 μm mammalian axon and an unmyelinated 1.5 μm pain fiber?
What is the difference between the speed of action potential conduction in a myelinated 8.6 μm mammalian axon and an unmyelinated 1.5 μm pain fiber?
Which of the following is a primary function of the myelin sheath?
Which of the following is a primary function of the myelin sheath?
What is the primary function of the nervous system?
What is the primary function of the nervous system?
What are the two types of nerves in the peripheral nervous system?
What are the two types of nerves in the peripheral nervous system?
What is the role of dendrites in a neuron?
What is the role of dendrites in a neuron?
What initiates the electrical impulse in the axon?
What initiates the electrical impulse in the axon?
What does the term 'membrane potential' refer to?
What does the term 'membrane potential' refer to?
Which ions are primarily involved in establishing membrane potential?
Which ions are primarily involved in establishing membrane potential?
What is the function of a synapse in neural communication?
What is the function of a synapse in neural communication?
Which cells can undergo rapid fluctuations in membrane potential?
Which cells can undergo rapid fluctuations in membrane potential?
What effect does the inactivation gate have on the Na+ channel during the action potential?
What effect does the inactivation gate have on the Na+ channel during the action potential?
Which ions are actively transported by the Na+–K+ ATPase pump?
Which ions are actively transported by the Na+–K+ ATPase pump?
What is the primary characteristic of graded potentials?
What is the primary characteristic of graded potentials?
What causes the influx of Na+ or Ca2+ in excitatory postsynaptic potentials (EPSPs)?
What causes the influx of Na+ or Ca2+ in excitatory postsynaptic potentials (EPSPs)?
What occurs during an inhibitory postsynaptic potential (IPSP)?
What occurs during an inhibitory postsynaptic potential (IPSP)?
What happens during the process of neurotransmitter release at the axon terminal?
What happens during the process of neurotransmitter release at the axon terminal?
What effect does hyperpolarization have on the postsynaptic cell?
What effect does hyperpolarization have on the postsynaptic cell?
Where in the neuron is the trigger zone typically located?
Where in the neuron is the trigger zone typically located?
What occurs during the falling phase of an action potential?
What occurs during the falling phase of an action potential?
Which statement is true regarding the absolute refractory period?
Which statement is true regarding the absolute refractory period?
What primarily causes the hyperpolarization of a neuron after an action potential?
What primarily causes the hyperpolarization of a neuron after an action potential?
Which function do the two gates of Na+ channels serve?
Which function do the two gates of Na+ channels serve?
Which phase is characterized by the membrane potential becoming positive?
Which phase is characterized by the membrane potential becoming positive?
What is required for a cell to fire during the relative refractory period?
What is required for a cell to fire during the relative refractory period?
What happens to Na+ channels during the repolarization phase?
What happens to Na+ channels during the repolarization phase?
How long does the refractory period last in a neuron?
How long does the refractory period last in a neuron?
What is the relationship between the strength of a graded potential and the frequency of action potentials triggered?
What is the relationship between the strength of a graded potential and the frequency of action potentials triggered?
What is the role of the trigger zone in the generation of an action potential?
What is the role of the trigger zone in the generation of an action potential?
Which of the following factors contributes to the decrease in strength of a graded potential as it travels through the cytoplasm?
Which of the following factors contributes to the decrease in strength of a graded potential as it travels through the cytoplasm?
Which of the following is TRUE about hyperpolarizing graded potentials?
Which of the following is TRUE about hyperpolarizing graded potentials?
Which of the following is NOT a characteristic of graded potentials?
Which of the following is NOT a characteristic of graded potentials?
Which of the following factors influences the speed of action potential conduction in unmyelinated axons?
Which of the following factors influences the speed of action potential conduction in unmyelinated axons?
What is the primary function of Myelin?
What is the primary function of Myelin?
How does the amount of neurotransmitter released at the axon terminal relate to the frequency of action potentials?
How does the amount of neurotransmitter released at the axon terminal relate to the frequency of action potentials?
During which phase of the action potential does the membrane potential become more negative than the resting potential?
During which phase of the action potential does the membrane potential become more negative than the resting potential?
What is the primary function of voltage-gated sodium channels during the action potential?
What is the primary function of voltage-gated sodium channels during the action potential?
What is the main difference between graded potentials and action potentials?
What is the main difference between graded potentials and action potentials?
Which of the following is considered a triggering event for an action potential?
Which of the following is considered a triggering event for an action potential?
What prevents action potentials from traveling backwards along the axon?
What prevents action potentials from traveling backwards along the axon?
What is the primary function of the sodium-potassium pump in maintaining the resting membrane potential?
What is the primary function of the sodium-potassium pump in maintaining the resting membrane potential?
What is the role of the threshold potential in action potential generation?
What is the role of the threshold potential in action potential generation?
Why is it essential for the membrane to become hyperpolarized during the action potential?
Why is it essential for the membrane to become hyperpolarized during the action potential?
Flashcards
What is the function of the nervous system?
What is the function of the nervous system?
The nervous system is a complex communication network that controls all vital functions of the body.
What is a neuron?
What is a neuron?
Neurons are the building blocks of the nervous system, responsible for transmitting information as electrical signals.
What are dendrites?
What are dendrites?
Dendrites are branched structures that receive incoming signals from other neurons and transmit them to the cell body.
What is the function of the cell body?
What is the function of the cell body?
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What is the axon?
What is the axon?
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What is a synapse?
What is a synapse?
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What are afferent nerves?
What are afferent nerves?
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What are efferent nerves?
What are efferent nerves?
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Threshold potential
Threshold potential
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Rising Phase of Action Potential
Rising Phase of Action Potential
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Falling Phase of Action Potential
Falling Phase of Action Potential
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Refractory Period
Refractory Period
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Absolute Refractory Period
Absolute Refractory Period
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Relative Refractory Period
Relative Refractory Period
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Activation Gate
Activation Gate
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Inactivation Gate
Inactivation Gate
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What makes nerve and muscle cells excitable?
What makes nerve and muscle cells excitable?
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What are the triggering events that initiate electrical signals in nerve and muscle cells?
What are the triggering events that initiate electrical signals in nerve and muscle cells?
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What are the two main types of electrical signals in nerve and muscle cells?
What are the two main types of electrical signals in nerve and muscle cells?
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How are action potentials generated?
How are action potentials generated?
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Describe the phases of an action potential.
Describe the phases of an action potential.
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Why can't action potentials travel backward?
Why can't action potentials travel backward?
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Describe the initial steps of an action potential.
Describe the initial steps of an action potential.
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What happens during the later stages of an action potential?
What happens during the later stages of an action potential?
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Myelin Sheath Function
Myelin Sheath Function
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Saltatory Conduction
Saltatory Conduction
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Action Potential Speed
Action Potential Speed
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Resistance & Conduction Velocity
Resistance & Conduction Velocity
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Capacitance & Conduction Velocity
Capacitance & Conduction Velocity
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Axon Diameter & Conduction Velocity
Axon Diameter & Conduction Velocity
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Conduction Velocity Comparison
Conduction Velocity Comparison
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Action Potential Travel Rate
Action Potential Travel Rate
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Na+ inactivation gate function
Na+ inactivation gate function
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Function of K+ channels
Function of K+ channels
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Na+-K+ ATPase pump function
Na+-K+ ATPase pump function
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What are Graded Potentials?
What are Graded Potentials?
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How are Graded Potentials generated?
How are Graded Potentials generated?
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What are Excitatory Postsynaptic Potentials (EPSPs)?”,
What are Excitatory Postsynaptic Potentials (EPSPs)?”,
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What are Inhibitory Postsynaptic Potentials (IPSPs)?
What are Inhibitory Postsynaptic Potentials (IPSPs)?
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How do graded potentials differ from action potentials?
How do graded potentials differ from action potentials?
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How do graded potentials respond to different stimuli?
How do graded potentials respond to different stimuli?
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What is the trigger zone?
What is the trigger zone?
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Why do graded potentials lose strength?
Why do graded potentials lose strength?
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How does axon diameter affect conduction speed?
How does axon diameter affect conduction speed?
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How does membrane resistance affect conduction speed?
How does membrane resistance affect conduction speed?
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Study Notes
1-The Nervous System
- The nervous system is a communication and control system regulating vital human body functions.
- It receives information from the environment and the body, interprets it, and causes the body to respond.
- The system is responsible for sensing stimuli such as temperature, taste, and texture, and processing emotional responses, including happiness, sadness, and anger.
- It regulates multiple human functions including movement, feeding, digestion, breathing and more.
- The building unit of the nervous system is the neuron.
2-The Neuron
- The cell body contains the nucleus, cytoplasm and plasma membrane.
- Dendrites extend from the cell body, connecting to other neurons. Dendrites receive information.
- The axon is a cylindrical structure covered by a myelin sheath, sending information to other neurons.
- Axon terminals are nerve endings; they send information to the next neuron; or muscle or gland.
- A synapse is a chemical junction between the axon terminal of one neuron and the dendrites of another neuron.
3-Neural Communication
- All body cells have a membrane potential; a separation of positive and negative charges across the membrane, related to the unequal distribution of ions, and selective permeability of the plasma membrane.
- Neurons and muscle cells can change their membrane potentials rapidly, acting as electrical signals in response to stimulation.
- A triggering event may be a chemical messenger interacting with the membrane's receptor, a stimulus (sound waves in the ears), or a change in ion channel permeability.
4-Electrical Signals
- Electrical signals are graded potentials and action potentials.
- Ion channels, including leak channels, voltage-gated channels, and ligand-gated channels, are essential in maintaining membrane potential.
4.1-Action potential.
- Ion permeability and movement: Voltage-gated ion channels open, changing the membrane's permeability to Na+ and K+, and creating the action potential.
- Phases of action potentials; Resting potential, depolarization, repolarization, and back to resting potential.
- Action potentials move in one direction.
4.2. Refractory Period
- The refractory period is the time after an action potential when the nerve cell cannot generate another action potential.
- Two phases of refractory period exist: absolute and relative refractory period.
4.3-Na+ Channels Gates
- Na+ channels maintain membrane potential and have two gates for regulating Na+ movement, the activation gate and the inactivation gate.
- Action potentials are caused by the rapid opening and closing of these two gates.
4.4-K+ Channels Gates
- K+ channels are responsible for the repolarization phase of the action potential.
4.5-The Na+-K+ ATPase pump
- The Na+/K+ pump maintains the resting potential by actively transporting 3 sodium ions out of the cell and bringing 2 potassium ions in.
5-Graded Potentials
- A graded potential results from a ligand-gated channel opening; it is a change in voltage based on the stimulus; it has varying degrees and moves short distances.
- Graded potentials can be excitatory (depolarizing) or inhibitory (hyperpolarizing), depending on the ions involved.
- Graded potentials lose strength as they travel due to current leak and cytoplasmic resistance.
- Graded potentials that reach the threshold at the trigger zone initiate an action potential.
6-Neurons Conduction Velocity in unmyelinated axon
- Two factors influence the speed of action potential conduction in a unmyelinated axon.
- Axon diameter and resistance to leakage of ions in the core.
7-Conduction in Myelinated Axons
- Myelinated axons limit contact with the extracellular fluid, increasing resistance and velocity.
- Action potentials in myelinated axons jump between nodes of Ranvier.
8-Conduction Velocity in Myelinated Axons
- Two factors influence the speed of propagation: resistance within the axon core and capacitance across the membrane.
- Larger axon diameters decrease internal resistance; decreasing capacitance increases velocity.
9-Examples of Conduction (action potential) velocity
- Myelinated axons can propagate action potentials much faster than unmyelinated axons.
10-Nerve Disease
- In demyelinating diseases, loss of myelin in neurons slows action potential conduction and may lead to conduction failure.
- Multiple sclerosis is a common demyelinating disease that causes various neurological problems.
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Description
Explore the intricate workings of the nervous system and its fundamental building block, the neuron. This quiz covers how the nervous system regulates body functions, processes stimuli, and enables emotional responses. Test your knowledge on the structure and function of neurons and their roles in communication within the body.