BIO 222 Chapter 2: Chromosomes and Reproduction
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Questions and Answers

List several characteristics that bacteria and archaea have in common and that distinguish them from eukaryotes.

Bacteria and archaea are prokaryotes. They differ from eukaryotes in that they have no nucleus, a single circular chromosomal genome (usually), and a smaller amount of DNA.

A virus is considered to be a prokaryote.

False (B)

Which of the following is NOT a characteristic of prokaryotes?

  • Membrane-bound organelles (correct)
  • Single circular chromosome
  • Smaller amount of DNA compared to eukaryotes
  • Unicellular
  • Which of the following is NOT a feature of eukaryotic chromosomes?

    <p>Circular structure (C)</p> Signup and view all the answers

    What is the function of kinetochores in eukaryotic chromosomes?

    <p>To attach to spindle microtubules (D)</p> Signup and view all the answers

    During which phase of the cell cycle does DNA replication occur?

    <p>S phase (D)</p> Signup and view all the answers

    Which of the following is a key transition point in the cell cycle, regulated by specific proteins that ensure the cell is ready to proceed to the next stage?

    <p>G1/S checkpoint (A)</p> Signup and view all the answers

    What is the main process that occurs during the M phase of the cell cycle?

    <p>Nuclear division and cell division (C)</p> Signup and view all the answers

    During which stage of mitosis do sister chromatids separate and migrate towards opposite poles?

    <p>Anaphase (C)</p> Signup and view all the answers

    The spindle microtubules, which are composed of tubulin subunits, play a crucial role in aligning chromosomes during mitosis.

    <p>True (A)</p> Signup and view all the answers

    What is the primary consequence of meiosis I?

    <p>Reduction of the chromosome number by half (A)</p> Signup and view all the answers

    During which stage of meiosis does crossing over occur, a process that generates genetic variation?

    <p>Prophase I (B)</p> Signup and view all the answers

    What is the significance of the random alignment of homologous chromosome pairs during metaphase I?

    <p>Contributes to genetic variation in gametes (A)</p> Signup and view all the answers

    Which of the following events takes place during meiosis II but not in meiosis I?

    <p>Separation of sister chromatids (C)</p> Signup and view all the answers

    Explain two major consequences of meiosis.

    <p>Meiosis produces four daughter cells from each original cell. However, the number of chromosomes in these daughter cells is reduced by half. The newly formed cells from meiosis are also genetically different from one another and from the parental cell.</p> Signup and view all the answers

    Which structure is diploid?

    <p>Microsporocyte (D)</p> Signup and view all the answers

    What is the difference between spermatogenesis and oogenesis?

    <p>Spermatogenesis is the production of sperm cells in males, while oogenesis is the production of egg cells in females.</p> Signup and view all the answers

    What is the ploidy level of the zygote?

    <p>Diploid (D)</p> Signup and view all the answers

    How does shugosin affect sister chromatids in meiosis I and meiosis II?

    <p>During anaphase I, shugoshin protects cohesin at the centromeres from the action of separase, preventing the separation of sister chromatids. However, during anaphase II, shugoshin breaks down, and cohesin at the centomeres is cleaved by separase, allowing the sister chromatids to separate.</p> Signup and view all the answers

    Which of the following processes is involved in the production of both sperm cells and egg cells?

    <p>Meiosis (B)</p> Signup and view all the answers

    Flashcards

    Prokaryotes

    Unicellular organisms lacking membrane-bound organelles. Their DNA is not organized into tightly packed chromosomes. Examples include bacteria and archaea.

    Eukaryotes

    Organisms with membrane-bound organelles, including a nucleus containing DNA organized into chromosomes. They can be unicellular or multicellular.

    Diploid cells

    Diploid cells contain two sets of chromosomes, one set from each parent.

    Haploid cells

    Haploid cells contain one set of chromosomes.

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    Centromere

    The point on a chromosome where spindle microtubules attach during cell division.

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    Telomeres

    The protective ends of linear chromosomes.

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    Origins of replication

    The specific locations on DNA where DNA replication begins.

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    Interphase

    The extended period between cell divisions in the cell cycle, where DNA synthesis and chromosome replication occur.

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    M phase

    The phase of the cell cycle where the replicated chromosomes separate and the cytoplasm divides.

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    Prophase

    The first stage of mitosis where chromosomes condense and the mitotic spindle forms.

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    Prometaphase

    The stage of mitosis where the nuclear envelope breaks down and spindle microtubules attach to chromosomes.

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    Metaphase

    The stage of mitosis where chromosomes align at the center of the cell.

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    Anaphase

    The stage of mitosis where sister chromatids separate and move to opposite poles.

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    Telophase

    The final stage of mitosis where chromosomes reach the poles, the nuclear envelope reforms, and the cytoplasm divides.

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    Cytokinesis

    The process of dividing the cytoplasm of a cell following mitosis or meiosis.

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    G1/S checkpoint

    A cell cycle checkpoint that ensures all conditions are favorable for DNA synthesis.

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    G2/M checkpoint

    A cell cycle checkpoint that ensures DNA replication is complete and undamaged before cell division.

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    Mitosis

    The process of cell division that produces two daughter cells genetically identical to the parent cell.

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    Meiosis

    The process of cell division that produces four haploid gametes (sex cells) from one diploid cell.

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    Fertilization

    The fusion of two haploid gametes to form a diploid zygote.

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    Synapsis

    The close pairing of homologous chromosomes during prophase I of meiosis.

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    Tetrad

    The four chromatids of two homologous chromosomes that are closely associated during prophase I of meiosis.

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    Crossing over

    The exchange of genetic information between non-sister chromatids of homologous chromosomes during prophase I of meiosis.

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    Random alignment of homologous chromosome pairs

    The random alignment of homologous chromosome pairs along the metaphase plate during metaphase I of meiosis.

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    Separation of homologous chromosome pairs

    The separation of homologous chromosome pairs during anaphase I of meiosis.

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    Spermatogenesis

    The process of producing male gametes (sperm cells).

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    Oogenesis

    The process of producing female gametes (egg cells).

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    Cohesin

    The protein that holds sister chromatids together during mitosis and meiosis.

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    Shugoshin

    A protein that protects centromeric cohesin from degradation during meiosis I.

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    Microsporocyte

    A diploid cell that undergoes meiosis to produce haploid microspores in plants.

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    Megasporocyte

    A diploid cell that undergoes meiosis to produce haploid megaspores in plants.

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    Study Notes

    Chapter 2: Chromosomes and Cellular Reproduction

    • The chapter covers prokaryotic and eukaryotic cells, cell reproduction, and sexual reproduction.
    • A prokaryotic cell lacks a nucleus and membrane-bound organelles. Its DNA is circular and not complexed with histones. Prokaryotes include bacteria and archaea.
    • Eukaryotic cells contain a nucleus and membrane-bound organelles. Their DNA is linear and complexed with histones to form chromosomes.
    • Prokaryotic cell division is simple division, separating replicated circular chromosomes from the origin of replication. It has a high rate of replication
    • Eukaryotic cell replication involves homologous pairs, chromosome structure, and the cell cycle.

    Eukaryotic Chromosomes

    • Homologous pairs: Diploid cells carry two sets of genetic information, with each set having similar chromosomes. Humans have 23 pairs.
    • Chromosome structure: At times, a chromosome consists of one chromatid, and at others, it consists of two sister chromatids. The centromere is the attachment point for spindle microtubules. The telomeres are the stable ends of chromosomes. Different types of chromosomes include submetacentric, metacentric, telocentric, and acrocentric.
    • Cell cycle: The cell grows, replicates DNA, and divides. Key transition points are the checkpoints: G1/S, G2/M. The cell cycle includes phases like G0, G1, S, G2, Mitosis (prophase, prometaphase, metaphase, anaphase, telophase), and Cytokinesis.

    Prokaryotic Cell Reproduction

    • Simple division: Prokaryotic cells divide by separating replicated circular chromosomes from an origin of replication. The process happens at a high rate.

    Eukaryotic Cell Replication

    • Cell cycle phases: G1: growth and development; S: DNA synthesis; G2: preparation for cell division. The cell cycle also includes mitosis (prophase, prometaphase, metaphase, anaphase, telophase) and cytokinesis. Mitosis is the active division of the nucleus and cytokinesis is the division of the cytoplasm. Multiple checkpoints regulate progression through the cell cycle
    • Genetic consequences of the cell cycle: The cycle produces two cells genetically identical to each other and to the original cell. Each new cell has a full complement of chromosomes.
    • The process occurs at a high rate of replication.
    • The mitosis phases are discussed as prophase, metaphase, anaphase, and telophase.
    • The mitosis separation of sister chromatids and homologous chromosomes involves an important protein: Cohesin.
    • Two types of cell divisions are covered: Mitosis (used for growth and repair in somatic cells) and Meiosis (used to produce gametes).

    Meiosis

    • Meiosis: The production of haploid gametes. Meiotic events include interphase (DNA synthesis and chromosome replication), Meiosis I (separation of homologous chromosome pairs), and Meiosis II (separation of sister chromatids). Each meiosis cycle has four phases: prophase, metaphase, anaphase, telophase. Interkinesis is an intermediate phase between meiosis 1 and 2
    • Crossing over: Crossing over of chromosome segments takes place during prophase I; this is the first mechanism of generating genetic variation.
    • Genetic variation: The random alignment of homologous chromosome pairs in meiosis I and crossing over in prophase I create genetic variation in gametes. Genetic variation ensures diversity.
    • Interkinesis: An intermediate phase occurring between meiosis 1 and 2
    • Meiosis: Meiosis has been described as a haploid cell division which results in four cells from a single cell

    Meiosis in the Life Cycle of Animals and Plants

    • Spermatogenesis: Male gamete production.
    • Oogenesis: Female gamete production.
    • Gametes are haploid reproductive cells.
    • Meiosis in plants: Plants often have different life cycles than animals in which the stages alternate between a single-celled haploid form and a multicellular diploid form. These terms are sporophyte (diploid form) and gametophyte (haploid form

    Viruses

    • Viruses lack both prokaryotic or eukaryotic characteristics and are surrounded by an outer protein coat that encompasses the nucleic acid.

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    Description

    This quiz covers essential concepts in Chapter 2, focusing on chromosomes, cellular reproduction, and the differences between prokaryotic and eukaryotic cells. Understand the structures and processes involved in cell division and the significance of homologous pairs in genetic information.

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