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What is the function of Thyroid Releasing Hormone (TRH) in the HPT axis?
What is the function of Thyroid Releasing Hormone (TRH) in the HPT axis?
What is the role of Triiodothyronine (T3) in the body?
What is the role of Triiodothyronine (T3) in the body?
What is the response of the thyroid gland when body temperature is low?
What is the response of the thyroid gland when body temperature is low?
What is the function of Thyroid Stimulating Hormone (TSH) in the HPT axis?
What is the function of Thyroid Stimulating Hormone (TSH) in the HPT axis?
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Where do thyroid hormones bind in the cell to influence gene transcription?
Where do thyroid hormones bind in the cell to influence gene transcription?
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What is the role of the anterior pituitary gland in the HPT axis?
What is the role of the anterior pituitary gland in the HPT axis?
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What is one of the functions of thyroid hormones in the body?
What is one of the functions of thyroid hormones in the body?
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What is the relationship between the hypothalamus and the anterior pituitary gland in the HPT axis?
What is the relationship between the hypothalamus and the anterior pituitary gland in the HPT axis?
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What is the effect of glucagon on glycogen?
What is the effect of glucagon on glycogen?
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What is the effect of insulin on glucose conversion?
What is the effect of insulin on glucose conversion?
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What is the main difference between Type 1 and Type 2 diabetes?
What is the main difference between Type 1 and Type 2 diabetes?
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What is a risk factor for Type 1 diabetes?
What is a risk factor for Type 1 diabetes?
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What is a symptom of diabetes mellitus?
What is a symptom of diabetes mellitus?
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What happens to glucose in the blood after a carbohydrate meal in diabetes mellitus?
What happens to glucose in the blood after a carbohydrate meal in diabetes mellitus?
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What is the effect of insulin on glucose conversion to fat?
What is the effect of insulin on glucose conversion to fat?
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What is a characteristic of Type 2 diabetes?
What is a characteristic of Type 2 diabetes?
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What is the term used to describe actions that correct changes in a factor?
What is the term used to describe actions that correct changes in a factor?
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What type of impulses are used by the nervous system in homeostatic control?
What type of impulses are used by the nervous system in homeostatic control?
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What is the role of the hypothalamus in homeostatic control?
What is the role of the hypothalamus in homeostatic control?
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What type of gland is the posterior pituitary?
What type of gland is the posterior pituitary?
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What is the function of the posterior pituitary hormones?
What is the function of the posterior pituitary hormones?
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What is the role of the hypothalamus in regulating anterior pituitary hormones?
What is the role of the hypothalamus in regulating anterior pituitary hormones?
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What is the function of prolactin-inhibiting hormone?
What is the function of prolactin-inhibiting hormone?
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What processes are controlled by hormones secreted by the anterior pituitary?
What processes are controlled by hormones secreted by the anterior pituitary?
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What is the primary function of the hypothalamus in the brain?
What is the primary function of the hypothalamus in the brain?
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What is the effect of too much T3 and T4 on the hypothalamus?
What is the effect of too much T3 and T4 on the hypothalamus?
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What is the term for the breakdown of glucose to produce more ATP?
What is the term for the breakdown of glucose to produce more ATP?
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What is the role of the thyroid gland in the HPT axis?
What is the role of the thyroid gland in the HPT axis?
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What is the result of negative feedback on metabolism?
What is the result of negative feedback on metabolism?
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What is the relationship between body temperature and T3 and T4?
What is the relationship between body temperature and T3 and T4?
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What is the role of the anterior pituitary gland in the HPT axis?
What is the role of the anterior pituitary gland in the HPT axis?
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What is the term for the control of body temperature?
What is the term for the control of body temperature?
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What is the primary function of homeostasis in living organisms?
What is the primary function of homeostasis in living organisms?
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Which of the following is NOT a physiological factor controlled by homeostasis in mammals?
Which of the following is NOT a physiological factor controlled by homeostasis in mammals?
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What is the role of the hypothalamus in hormone regulation?
What is the role of the hypothalamus in hormone regulation?
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What is the term for the process by which the body returns to a stable state after a change?
What is the term for the process by which the body returns to a stable state after a change?
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What is the primary function of insulin in blood glucose regulation?
What is the primary function of insulin in blood glucose regulation?
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What is the role of glucagon in blood glucose regulation?
What is the role of glucagon in blood glucose regulation?
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What is the difference between type 1 and type 2 diabetes?
What is the difference between type 1 and type 2 diabetes?
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What is the role of cyclic AMP as a second messenger in blood glucose regulation?
What is the role of cyclic AMP as a second messenger in blood glucose regulation?
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Study Notes
Homeostasis
- Homeostasis is the maintenance of a constant internal environment for life functions despite changes in the external environment.
- Physiological factors controlled in mammals include:
- Core body temperature
- Metabolic wastes (e.g. carbon dioxide and urea)
- Blood pH
- Blood glucose concentration
- Water potential of the blood
- Concentrations of respiratory gases (oxygen and carbon dioxide) in the blood
- Homeostasis involves corrective actions that correct or reverse changes in these factors.
Homeostatic Control
- There are two coordination systems in mammals that are involved in homeostatic control:
- Nervous system (electrical impulses)
- Endocrine system (chemical messengers)
Structure of Homeostasis
- The hypothalamus receives information from nerves, processes it, and sends signals to the pituitary gland.
- The pituitary gland is located at the base of the hypothalamus and synthesizes and secretes hormones in response to hormones from the hypothalamus.
- The posterior pituitary is an extension of the hypothalamus and secretes neurohormones synthesized in the hypothalamus.
- The anterior pituitary is an endocrine gland that synthesizes and secretes hormones in response to hormones from the hypothalamus.
Posterior Pituitary Hormones
- Two posterior pituitary hormones are:
- Antidiuretic hormone (ADH)
- Oxytocin
- These neurohormones are stored and released in response to nerve impulses transmitted by the hypothalamus.
Anterior Pituitary Hormones
- Hormones secreted by the anterior pituitary control diverse processes in the human body, including:
- Metabolism
- Osmoregulation
- Reproduction
- Hypothalamus regulates each set of hormones by using releasing or inhibiting hormones on the anterior pituitary gland.
Thyroid Regulation
- Thyroid regulation involves the HPT axis, which includes the hypothalamus, pituitary gland, and thyroid gland.
- The hypothalamus produces thyroid-releasing hormone (TRH), which stimulates the anterior pituitary gland to produce thyroid-stimulating hormone (TSH).
- TSH stimulates the thyroid gland to produce thyroid hormones (T3 and T4).
- Thyroid hormones regulate metabolism, growth, and development.
Thermoregulation
- Thermoregulation is the control of body temperature, which involves both the nervous and endocrine systems.
- The hypothalamus is the central control for body temperature.
- When the body temperature is too low, the thyroid gland increases the production of thyroid hormones, which leads to an increase in metabolism and heat production.
Blood Glucose Regulation
- Blood glucose regulation involves the balance between insulin and glucagon.
- Insulin:
- Converts glucose to glycogen
- Increases the rate of glucose conversion to glycogen
- "Traps" glucose into cells
- Increases the rate of glucose conversion to fat and stored in adipose tissue
- Glucagon:
- Converts glycogen to glucose
- Increases the rate of gluconeogenesis
Diabetes
- Diabetes mellitus is a metabolic disease characterized by high blood glucose levels.
- There are two types of diabetes:
- Type 1 diabetes (insulin-dependent diabetes):
- Beta cells do not produce insulin
- Viral infection, autoimmune response, and genetics are risk factors
- Type 2 diabetes (non-insulin-dependent diabetes):
- Insulin is produced, but target cells do not respond to it adequately
- Obesity, genetic link, and a diet high in sugars are risk factors
- Type 1 diabetes (insulin-dependent diabetes):
- Symptoms of diabetes include:
- High glucose levels in the blood and urine
- Increased hunger and thirst
- Frequent urination
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Description
Quiz on homeostasis, covering principles, examples, and its role in mammals. Includes topics on dwarfism and giantism.