Biology 1050 Final Exam Study Guide
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Questions and Answers

The sequence of amino acids in a protein is referred to as its primary structure.

True (A)

Regardless of the amino acid to be bound to a tRNA molecule, all tRNA molecules use the same sequence at their 3' end to serve as the amino acid attachment site.

True (A)

Which is a function of the signal-recognition particle (SRP)?

  • The SRP direct proteins to the nuclear pores of the nuclear envelope.
  • The SRP speeds up translation.
  • The SRP binds to sugars added to proteins in the Golgi apparatus.
  • The SRP binds to the SRP receptor on the rough endoplasmic reticulum. (correct)

Structurally and functionally related groups of proteins are referred to as:

<p>families (B)</p> Signup and view all the answers

Which one of the statements about translation in eukaryotes is correct?

<p>An initiation complex recognizes a 5' cap structure and scans for the first AUG triplet. (C)</p> Signup and view all the answers

Some enzymes are translated in the cytosol but remain inactive until they are phosphorylated by another enzyme, a kinase. Once they are phosphorylated, these enzymes become active. The phosphorylation of the enzyme would be considered a posttranslational modification.

<p>True (A)</p> Signup and view all the answers

There is approximately the same number of protein families as there are folding domains.

<p>True (A)</p> Signup and view all the answers

The tRNA that binds the start codon has the sequence ______ at its ______.

<p>5'-AUG-3'; anticodon (A)</p> Signup and view all the answers

Flashcards

Primary structure of a protein

The sequence of amino acids in a protein chain.

tRNA amino acid attachment site

tRNA's 3' end, which carries the amino acid.

Signal-recognition particle (SRP) function

Binds to the signal sequence of proteins destined for the ER and targets them there.

Protein families definition

Structurally and functionally related groups of proteins.

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Eukaryotic translation initiation

The ribosome recognizes the 5' cap and scans for the AUG start codon.

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Post-translational modification (phosphorylation)

Enzyme activation by adding a phosphate group after translation.

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Protein families vs. folding domains

Different numbers exist. Not equal.

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Start codon tRNA sequence

5'-UAC-3' on tRNA; at the amino acid attachment site.

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Primary structure of a protein correct?

True, the sequence of amino acids.

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Same tRNA for all amino acids?

False, different tRNA for each amino acid.

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SRP function (multiple choice)

Binds to the SRP receptor on the rough ER to target protein.

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Eukaryotic translation mRNA

mRNA with 5' cap and 3'UTR. AUG start codon.

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Correct translation termination

Ribosome reaches the stop codon on mRNA.

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Study Notes

Biology 1050 Final Exam Study Notes

  • Primary Protein Structure: The sequence of amino acids.
  • tRNA Amino Acid Attachment Site: All tRNA molecules use the same 3' end for amino acid attachment, regardless of the amino acid.
  • Signal-Recognition Particle (SRP) Function: The SRP binds to the SRP receptor on the rough endoplasmic reticulum, directing proteins there.
  • Structurally and Functionally Related Proteins: Called protein families or domains.
  • Eukaryotic Translation: The initiation complex recognizes the 5' cap and scans for the first AUG triplet. Translation continues until the ribosome reaches the end of the mRNA.
  • Post-Translational Modification: Phosphorylation of an enzyme by a kinase is a post-translational modification.
  • Protein Families and Folding Domains: There is approximately the same number of protein families as there are folding domains.
  • Start Codon tRNA Sequence: The tRNA that binds the start codon (AUG) has the sequence 5'-AUG-3' which is the anticodon.

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Prepare for your Biology 1050 final exam with this comprehensive study guide. Cover essential topics such as protein structure, translation, and post-translational modifications. Review key concepts including the functions of tRNA and signal-recognition particles to ensure a solid understanding of molecular biology.

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