BIOL214 Week 2: Glycolysis

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Questions and Answers

What is the energy currency of organisms?

  • ATP (correct)
  • Glucose
  • Pyruvate
  • NAD+

Glycolysis occurs in the ______ of every cell.

cytosol

Which of the following are the three major stages of cellular respiration? (Select all that apply)

  • Electron transfer/oxidative phosphorylation (correct)
  • Acetyl CoA production (correct)
  • Acetyl CoA oxidation (correct)
  • Photosynthesis

How many ATP are produced from one glucose molecule in theory?

<p>38</p> Signup and view all the answers

What is the molecular mass of glucose?

<p>180.16 g/mol</p> Signup and view all the answers

Cellular respiration occurs in the cytoplasm only.

<p>False (B)</p> Signup and view all the answers

The reduction of ______ is a feature of the glycolysis pathway.

<p>NAD+</p> Signup and view all the answers

What is produced during glycolysis?

<p>ATP and pyruvate</p> Signup and view all the answers

Match the terms with their meanings:

<p>Glycolysis = Breaking down glucose Acetyl CoA = A key metabolic intermediate NAD+ = Electron carrier Pyruvate = End product of glycolysis</p> Signup and view all the answers

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Study Notes

Overview of Glycolysis

  • Glycolysis is the first stage of cellular respiration, occurring in the cytosol of all cells.
  • It plays a crucial role in breaking down glucose into pyruvate, facilitating energy production.

Lecture Objectives

  • Reintroduce the concept of cellular respiration.
  • Understand the essential features of the glycolysis pathway, including:
    • Reduction of NAD+ to NADH.
    • Production of ATP.
    • Formation of pyruvate.
  • Identify vital steps in the glycolysis process.
  • Explore alternative metabolic fates of pyruvate.

Stages of Cellular Respiration

  • Cellular respiration comprises three major stages:
    • Acetyl CoA production (glycolysis).
    • Acetyl CoA oxidation (TCA cycle).
    • Electron transfer and oxidative phosphorylation.

ATP Production Example

  • From 5.45 grams of glucose, a calculation demonstrates the potential ATP yield:
    • Molecular mass of glucose: 180.16 g/mol.
    • Moles of glucose from 5.45 g: approximately 0.03025 moles.
    • Total molecules of glucose: approximately 1.822 x 10^22 molecules.
    • Each glucose molecule can produce up to 38 ATP molecules.
    • Total ATP produced from this amount: approximately 6.92 x 10^23 ATP molecules, highlighting the extensive energy yield even at 50% efficiency.

Glycolysis Terminology

  • The word "glycolysis" is derived from Greek:
    • "Glykis" means sweet, referring to sugars.
    • "Lysis" means splitting, indicating the breakdown process.

Locations of Key Metabolic Processes

  • Glycolysis occurs in the cytoplasm.
  • Acetyl CoA oxidation occurs in the mitochondrial matrix.
  • Oxidative phosphorylation takes place in the inner mitochondrial membrane.

Importance of Metabolism

  • Metabolism functions collectively, with the breakdown of carbohydrates being a foundational aspect.
  • Other precursors for energy production include amino acids and glycerol, enhancing metabolic versatility.

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