Podcast
Questions and Answers
Where does glycolysis occur in cells?
Where does glycolysis occur in cells?
- Mitochondria
- Nucleus
- Endoplasmic Reticulum
- Cytosol (correct)
What is the primary fuel source for erythrocytes?
What is the primary fuel source for erythrocytes?
- Lipids
- Amino Acids
- Proteins
- Glucose (correct)
Which enzyme complex is required for glucose oxidation beyond pyruvate?
Which enzyme complex is required for glucose oxidation beyond pyruvate?
- Hexokinase
- Pyruvate Dehydrogenase Complex (correct)
- Isocitrate Dehydrogenase
- Pyruvate Kinase
What may account for the high rate of glycolysis in cancer cells?
What may account for the high rate of glycolysis in cancer cells?
Why might methylglyoxal inhibit GAPDH in cancer cells but not in normal cells?
Why might methylglyoxal inhibit GAPDH in cancer cells but not in normal cells?
What is the main function of skeletal muscle in storing glycogen?
What is the main function of skeletal muscle in storing glycogen?
During gluconeogenesis in the liver, what substrates can be converted to glucose?
During gluconeogenesis in the liver, what substrates can be converted to glucose?
In what scenario does skeletal muscle perform at very high levels of work output using glycolysis?
In what scenario does skeletal muscle perform at very high levels of work output using glycolysis?
Which process maintains blood glucose levels between meals?
Which process maintains blood glucose levels between meals?
Where do most of the metabolic pathways like glycolysis and fatty acid synthesis occur within the muscle cell?
Where do most of the metabolic pathways like glycolysis and fatty acid synthesis occur within the muscle cell?
In starvation, what percentage of energy needs of the brain can be met by ketone bodies?
In starvation, what percentage of energy needs of the brain can be met by ketone bodies?
Which tissue has the most substantial requirement for glucose?
Which tissue has the most substantial requirement for glucose?
What is the major fuel for most tissues?
What is the major fuel for most tissues?
Which pathway metabolizes glucose to pyruvate?
Which pathway metabolizes glucose to pyruvate?
What is the end product of anaerobic glycolysis?
What is the end product of anaerobic glycolysis?
What is the precursor of fatty acids and cholesterol?
What is the precursor of fatty acids and cholesterol?
Which process utilizes glucose as a fuel in skeletal muscle?
Which process utilizes glucose as a fuel in skeletal muscle?
What does aerobic metabolism of glucose in tissues form?
What does aerobic metabolism of glucose in tissues form?
What is the end product of glycolysis in fast-growing cancer cells?
What is the end product of glycolysis in fast-growing cancer cells?
What enzyme catalyzes the phosphorylation of glucose to glucose-6-phosphate in glycolysis?
What enzyme catalyzes the phosphorylation of glucose to glucose-6-phosphate in glycolysis?
What causes lactic acidosis in some scenarios?
What causes lactic acidosis in some scenarios?
Which molecule allosterically inhibits hexokinase in glycolysis?
Which molecule allosterically inhibits hexokinase in glycolysis?
What process is responsible for much of the hypermetabolism seen in cancer cachexia?
What process is responsible for much of the hypermetabolism seen in cancer cachexia?
Under what conditions does mitochondrial re-oxidation of NADH formed during glycolysis become impaired?
Under what conditions does mitochondrial re-oxidation of NADH formed during glycolysis become impaired?
What inhibits enolase?
What inhibits enolase?
Why is pyruvate kinase reaction irreversible under physiological conditions?
Why is pyruvate kinase reaction irreversible under physiological conditions?
What happens to pyruvate under anaerobic conditions?
What happens to pyruvate under anaerobic conditions?
What facilitates the oxidation of NADH under anaerobic conditions?
What facilitates the oxidation of NADH under anaerobic conditions?
What happens to pyruvate under aerobic conditions?
What happens to pyruvate under aerobic conditions?
Which ion is Enolase dependent on for its activity?
Which ion is Enolase dependent on for its activity?
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