BIOL*1080 Lecture 1: Systems Biology

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What does the Paleolithic diet suggest about our modern lifestyle?

It signals to our bodies that we're injured and need to slow down metabolism.

What is the focus of Integrative Medicine (IM) according to the text?

Healing the whole person, including all aspects of lifestyle.

What does One Health, as mentioned in the text, aim to address?

Collaborative effort on complex animal, human, and environmental health problems.

What aspect of biological systems is considered from the dimension of time in Lecture 5?

Rhythms – maintenance/repair, other processes.

What does 'in vivo' refer to in the given text?

A whole-body or organism approach

What is the possible conclusion drawn from the data on leptin's effect on fat oxidation in muscle?

Leptin administration will help with weight loss

What does the 'reduction' model using single leg extensions help to study?

Training effects on VO2 max in the absence of 'systemic changes'

Why have clinical trials with leptin not been very successful according to the text?

Overweight individuals become leptin resistant

What is the main goal of systems biology?

To better understand the entirety of the processes in a biological system

What are emergent properties in the context of systems biology?

Properties of an entire system that are not necessarily evident from examining individual components

What is the main purpose of omics in systems biology?

To incorporate many levels such as genes, proteins, tissues, and organ systems

What does systems biology involve in order to predict outcomes or responses in a living system?

Bioinformatics and complex mathematical modeling

Explore the main goal of systems biology and its systematic study of complex interactions in biological systems. This lecture also covers the overall objective of the course, which is to consider health, disease, and aging in the adult human from a systems biology perspective.

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