22 Questions
What is the main function of connexons in gap junctions?
Allow direct communication between adjacent cells
Which type of intercellular communication involves gap junctions?
Direct communication
What is a characteristic feature of the pore size in gap junctions?
Very small
Which of the following molecules can pass through gap junctions?
Sugars, amino acids, & ions
In intercellular communication, what do connexons permit between cells?
Passage of small molecules
What type of intercellular communication involves the transfer of nucleic acids and small organelles between cells?
Membrane nanotubes
Which intercellular communication type can be acutely regulated by phosphorylation and dephosphorylation?
Gap junctions
In which type of muscle, such as cardiac muscle, are intercalated disks found, allowing for rapid and coordinated propagation of action potentials?
Cardiac muscle
Which mechanism involves the conversion of mechanical stimuli into a cellular response?
Mechanosignal transduction
What can excessive pulsatile and shearing stresses from blood flow on arterial endothelial cells mediate?
Vascular inflammation
Which communication type involves indirect intercellular signaling through chemical messengers?
Chemical messengers
Which type of chemical messenger acts on a nearby cell?
Paracrine signaling
What type of hormones typically dissolve in plasma and do not require a carrier for transportation?
Hydrophilic hormones
Which type of hormone needs a carrier for transportation as they cannot dissolve in plasma?
Steroid hormones
What is a key requirement for neurotransmitter signals to be tightly controlled?
Auto shutoff mechanism
Which type of communication is considered more direct in terms of intercellular signaling?
Paracrine signaling
What is the storage characteristic of hydrophobic hormones like cortisol?
They are made on demand
What is the goal of receptor amplification?
To change the overall profile of cellular protein/enzymatic activity
Where do hydrophilic chemical messengers typically bind?
Cell surface (plasma membrane)
How do hydrophobic chemical messengers primarily exert their effects?
By turning on genes to make new proteins
What is the role of Student Accessibility Services (SAS) on campus?
Supporting students with well-being services
Where can students find support related to health and performance on campus?
Student Health Services Health & Performance Centre (HPC)
Test your knowledge on mechanisms of intercellular communication including gap junctions, membrane nanotubes, and mechanosignals. The quiz is based on lectures 1-6 and consists of 25 multiple choice questions. Prepare by reviewing the course material before the exam.
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