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Biochemistry: PFK-1 Reaction Regulation
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Biochemistry: PFK-1 Reaction Regulation

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Questions and Answers

What inhibits hexokinase isozymes I, II, and III?

  • Acetyl-CoA
  • Fructose 2,6-bisphosphate
  • Long-chain fatty acids
  • G6P (correct)

    • Which enzyme forms G6P in the liver for glycogen synthesis?

  • Hexokinase II
  • Pyruvate kinase
  • Glucokinase (correct)
  • Phosphofructokinase-1

    • Which allosteric regulator inhibits Phosphofructokinase-1?

  • Long chain fatty acids
  • AMP
  • Citrate (correct)
  • Fructose 2,6-bisphosphate

    • What triggers Pyruvate Kinase activation?

    <p>Accumulation of F1,6BP</p> Signup and view all the answers

    How is Pyruvate Kinase allosterically inhibited?

    <p>Long-chain fatty acids</p> Signup and view all the answers

    Which enzyme is controlled by covalent modification and allosteric regulation?

    <p>$ ext{Pyruvate Kinase}$</p> Signup and view all the answers

    $ ext{Enolase}$ inhibitors are part of the inhibitors of glycolysis. What specifically do these inhibitors target?

    <p>$ ext{Enolase itself}$</p> Signup and view all the answers

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