Biochemistry Module 1 Quiz

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Questions and Answers

Which of the following is NOT a type of protein structure?

  • Tertiary
  • Quaternary (correct)
  • Secondary
  • Primary

Which of the following amino acid modifications is NOT commonly found in proteins?

  • Phosphorylation
  • Hydrogenation (correct)
  • Methylation
  • Glycosylation

Which of the following is a key characteristic of a transmissible spongiform encephalopathy (TSE)?

  • Treatable with antibiotics
  • Prions cause misfolding of proteins (correct)
  • High fever and flu-like symptoms
  • Caused by a virus

What is the name of the process that removes a water molecule during the formation of a peptide bond?

<p>Dehydration (B)</p> Signup and view all the answers

Which type of inhibitor binds to the enzyme active site and prevents the substrate from binding?

<p>Competitive (B)</p> Signup and view all the answers

Which of the following is NOT a characteristic of a lipid?

<p>Acts as a primary energy source for cells (B)</p> Signup and view all the answers

Which of the following is a type of transmembrane protein involved in neurotransmitter release?

<p>SNAREs (C)</p> Signup and view all the answers

What type of transport does NOT require energy to move molecules across the cell membrane?

<p>Passive transport (B)</p> Signup and view all the answers

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Flashcards

Hydrolysis

A chemical process that splits molecules by adding water, essential for digestion.

Natural Selection

The process where organisms better adapted to their environment tend to survive and produce more offspring.

Peptide Formation

The chemical bond formed between two amino acids during protein synthesis.

Michaelis-Menten Kinetics

A model describing the rate of enzymatic reactions, characterized by Km and Vmax.

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Lipid Bilayer

A double layer of lipids that forms the foundation of cell membranes, controlling permeability.

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Zwitterions

Molecules that have both positive and negative charges, characteristic of amino acids in physiological pH.

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Fluid Mosaic Model

A model describing the structure of cell membranes as a mosaic of diverse proteins floating in a fluid lipid bilayer.

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Osmosis

The diffusion of water across a selectively permeable membrane from a region of low solute concentration to high solute concentration.

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Study Notes

Module 1 Material

  • Chapter 1: Covers hydrolysis, compartmentation, natural selection, evolution, cell sizes, cell components, and the differences between viruses, prokaryotes, eukaryotes, and archaea, including thermodynamics and units.

Module 1 Material - Chapter 2

  • Chapter 2: Focuses on the hydrophobic effect, osmosis, water structure/properties, and bonding types (hydrogen, London dispersion, hydrophobic, ionic). Key concepts include pKa, pH values, amphiphiles, and ion mobility, along with Kw values.

Module 1 Material - Chapter 3

  • Chapter 3: Details amino acids (structure, groupings, pKas, modifications), protein structure, amino acid pairings, chirality, zwitterions, peptide formation, and drugs.

Module 1 Material - Chapter 4

  • Chapter 4: Explores protein structure (alpha-helices, beta-sheets, beta-strands, beta-hairpins, disulfides, folding), oligomeric and globular proteins, collagen, Alzheimer's plaques, transmissible spongiform encephalopathies, prions, and 3D protein structural determination.

Module 2 Material - Chapter 9

  • Chapter 9: Covers catalysis, enzyme-substrate interactions, lysozymes, serine protease (steps and tetrahedral intermediates), RNase, enzyme classification, delta-G, transition states, nucleophilicity, and metalloenzymes.

Module 2 Material - Chapter 10

  • Chapter 10: Focuses on Michaelis-Menten kinetics (Km, Kcat, Vmax, Vo, etc.), inhibitors (types, plots, Ki), noncovalent modifications, and regulation in enzyme reactions, including reaction orders, rate of elementary reactions, steady-state kinetics, and ATCase's T and R states.

Module 3 Material - Chapter 5

  • Chapter 5: Outlines sugar structures (structures, isomers, polymers), amylopectin, amylose, hyaluronic acid, cellulose, chitin, peptidoglycans, glycosylation, hemiacetals, uronic acid, sialic acid, and peptidoglycans, as well as artificial sweeteners.

Module 3 Material - Chapter 7

  • Chapter 7: Discusses lipids (structures, locations, properties), cholesterol, and lipid bilayers.

Module 3 Material - Chapter 8

  • Chapter 8: Covers transmembrane proteins, micelles, adipocytes, biconcave structure, fluid-mosaic models, translocons, vitamin D, SNAREs, I-cells, Botox, clathrin, endocytosis, and palmitolyation. It also details transporter types, uses, differences, common molecules that can pass through (neurotransmitters, gap junctions, diffusion, and aquaporins).

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