Biochemistry Lecture 9: Common GI Disorders
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Questions and Answers

What is the major site of lactate production in the human body?

  • Skeletal muscle (correct)
  • Liver
  • Spleen
  • Kidney
  • What is the normal range for plasma lactate concentration?

  • $3.5–4.2$ mmol/L
  • $0.5–2.2$ mmol/L (correct)
  • $4.5–5.2$ mmol/L
  • $2.5–3.2$ mmol/L
  • Which deficiency is the most common biochemical cause of congenital lactic acidosis?

  • Folic acid deficiency
  • Vitamin D deficiency
  • Pyruvate dehydrogenase complex deficiency (correct)
  • Vitamin B12 deficiency
  • What is the main treatment for lactic acidosis caused by lack of oxygen?

    <p>Rest and rehydration</p> Signup and view all the answers

    What represents a novel therapy that can reduce transfusion burden in some adults with pyruvate kinase deficiency receiving regular transfusions?

    <p>Mitapivat</p> Signup and view all the answers

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