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Questions and Answers
What is the major site of lactate production in the human body?
What is the major site of lactate production in the human body?
- Skeletal muscle (correct)
- Liver
- Spleen
- Kidney
What is the normal range for plasma lactate concentration?
What is the normal range for plasma lactate concentration?
- $3.5–4.2$ mmol/L
- $0.5–2.2$ mmol/L (correct)
- $4.5–5.2$ mmol/L
- $2.5–3.2$ mmol/L
Which deficiency is the most common biochemical cause of congenital lactic acidosis?
Which deficiency is the most common biochemical cause of congenital lactic acidosis?
- Folic acid deficiency
- Vitamin D deficiency
- Pyruvate dehydrogenase complex deficiency (correct)
- Vitamin B12 deficiency
What is the main treatment for lactic acidosis caused by lack of oxygen?
What is the main treatment for lactic acidosis caused by lack of oxygen?
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What represents a novel therapy that can reduce transfusion burden in some adults with pyruvate kinase deficiency receiving regular transfusions?
What represents a novel therapy that can reduce transfusion burden in some adults with pyruvate kinase deficiency receiving regular transfusions?
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