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10 Questions

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Biochemistry Lecture 5: Liver Disorders

Created by

@VibrantTucson

Questions and Answers

What is the percentage of people with Gilbert's syndrome who are asymptomatic?

One third

One quarter (correct)

Two thirds

One half

What is the primary reason for people with Gilbert's syndrome to undergo blood tests?

To monitor the progression of the disease

To diagnose Gilbert's syndrome

To rule out other health conditions

To check for a different problem (correct)

What is the typical outcome of blood tests for people with Gilbert's syndrome?

They are diagnosed with a different disease

They are diagnosed with Gilbert's syndrome (correct)

They are referred to a specialist for further evaluation

They are found to have no underlying health issues

What is the relationship between Gilbert's syndrome and symptoms?

Some people with Gilbert's syndrome exhibit symptoms Signup and view all the answers

What is the purpose of blood tests in people with Gilbert's syndrome?

To check for a different problem that may be causing symptoms Signup and view all the answers

What is the frequency of asymptomatic people with Gilbert's syndrome?

One in three Signup and view all the answers

What is the outcome of blood tests for people who are asymptomatic but have Gilbert's syndrome?

They are diagnosed with Gilbert's syndrome Signup and view all the answers

What is the primary reason for people with Gilbert's syndrome to seek medical attention?

They are seeking a diagnosis for a different problem Signup and view all the answers

What is the relationship between Gilbert's syndrome and blood tests?

Blood tests are used to diagnose Gilbert's syndrome in people without symptoms Signup and view all the answers

What is the most common reason for people to discover they have Gilbert's syndrome?

They are seeking a diagnosis for a different problem Signup and view all the answers

Study Notes

Liver Disorders: Case Studies

A 49-year-old woman presents with an 8-day history of anorexia, nausea, and flu-like symptoms, with dark urine; physical examination reveals tenderness in the right upper quadrant of the abdomen.

Liver Function Tests (LFTs) Results

Elevated AST and ALT, indicating liver damage
High ALP, suggesting cholestasis
Diagnosis: viral hepatitis

Gilbert's Syndrome

A 43-year-old healthy male presents with elevated bilirubin levels
Bilirubin levels are elevated due to decreased enzyme activity (UGT1A1 gene mutation)
As a result, bilirubin builds up in the blood, causing hyperbilirubinemia
Approximately 1 in 3 people with Gilbert's syndrome do not exhibit symptoms
Diagnosis is often incidental, discovered through blood tests for other conditions