Biochemistry Final 1st Attempt 2023 - Buffering Capacity and Amino Acids

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Questions and Answers

Which amino acid would provide the greatest buffering capacity at physiologic pH?

  • Serine
  • Arginine
  • Histidine (correct)
  • Lysine

Which amino acid cannot be found in proteins?

  • Lysine
  • Hydroxylysine
  • Proline
  • β-alanine (correct)

What characteristic of glycine makes it suitable as the initial amino acid in the Gly-X-Y repeat of collagen peptides?

  • Large hydrophobic side chain
  • Strongly basic side chain
  • Small size and flexibility (correct)
  • Highly acidic side chain

Which property of an amino acid would promote its binding in a protein structure?

<p>Basic side groups to promote binding (C)</p> Signup and view all the answers

Why is the affinity of fetal hemoglobin for oxygen higher than that of adult hemoglobin?

<p>There is less 2,3-BPG in the fetal circulation as compared to maternal circulation (B)</p> Signup and view all the answers

What could explain a 35-year-old farmer's methemoglobin levels of 20%?

<p>Nitrates in well water (B)</p> Signup and view all the answers

What is the rate-limiting enzyme in catecholamine biosynthesis?

<p>L-DOPA decarboxylase (D)</p> Signup and view all the answers

On what does enzymatic reaction velocity depend?

<p>Temperature, pH and substrate concentrations (A)</p> Signup and view all the answers

Which statement about the Michaelis constant (Km) is correct?

<p>Km increases in the presence of noncompetitive inhibitors (D)</p> Signup and view all the answers

How do statin drugs inhibit de novo synthesis of cholesterol?

<p>They are a competitive inhibitor of HMG-CoA reductase (C)</p> Signup and view all the answers

Which coenzyme cooperates with dehydrogenases?

<p>All the above can cooperate with dehydrogenases (A)</p> Signup and view all the answers

How can some enzymes be regulated by covalent modification?

<p>Phosphorylation by protein kinases (C)</p> Signup and view all the answers

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