Biochemistry Final 1st Attempt 2023 - Buffering Capacity and Amino Acids
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Questions and Answers

Which amino acid would provide the greatest buffering capacity at physiologic pH?

  • Serine
  • Arginine
  • Histidine (correct)
  • Lysine
  • Which amino acid cannot be found in proteins?

  • Lysine
  • Hydroxylysine
  • Proline
  • β-alanine (correct)
  • What characteristic of glycine makes it suitable as the initial amino acid in the Gly-X-Y repeat of collagen peptides?

  • Large hydrophobic side chain
  • Strongly basic side chain
  • Small size and flexibility (correct)
  • Highly acidic side chain
  • Which property of an amino acid would promote its binding in a protein structure?

    <p>Basic side groups to promote binding</p> Signup and view all the answers

    Why is the affinity of fetal hemoglobin for oxygen higher than that of adult hemoglobin?

    <p>There is less 2,3-BPG in the fetal circulation as compared to maternal circulation</p> Signup and view all the answers

    What could explain a 35-year-old farmer's methemoglobin levels of 20%?

    <p>Nitrates in well water</p> Signup and view all the answers

    What is the rate-limiting enzyme in catecholamine biosynthesis?

    <p>L-DOPA decarboxylase</p> Signup and view all the answers

    On what does enzymatic reaction velocity depend?

    <p>Temperature, pH and substrate concentrations</p> Signup and view all the answers

    Which statement about the Michaelis constant (Km) is correct?

    <p>Km increases in the presence of noncompetitive inhibitors</p> Signup and view all the answers

    How do statin drugs inhibit de novo synthesis of cholesterol?

    <p>They are a competitive inhibitor of HMG-CoA reductase</p> Signup and view all the answers

    Which coenzyme cooperates with dehydrogenases?

    <p>All the above can cooperate with dehydrogenases</p> Signup and view all the answers

    How can some enzymes be regulated by covalent modification?

    <p>Phosphorylation by protein kinases</p> Signup and view all the answers

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