Podcast
Questions and Answers
Which enzyme catalyzes the formation of carbamoyl phosphate for urea synthesis, using NH4+?
Which enzyme catalyzes the formation of carbamoyl phosphate for urea synthesis, using NH4+?
- Argininosuccinate lyase
- Ornithine transcarbamoylase
- Argininosuccinate synthetase
- Carbamoyl phosphate synthetase II (correct)
What is the reference level of urea in the blood plasma?
What is the reference level of urea in the blood plasma?
- 10-15 mM
- 20-30 mM (correct)
- 5-9 mM
- 1-3 mM
Which amino acid stimulates the synthesis of N-acetylglutamate, which activates carbamoyl phosphate synthetase I in the short-term regulation of the urea cycle?
Which amino acid stimulates the synthesis of N-acetylglutamate, which activates carbamoyl phosphate synthetase I in the short-term regulation of the urea cycle?
- Arginine (correct)
- Aspartate
- Alanine
- Glutamine
Where does the cycle of urea production begin?
Where does the cycle of urea production begin?
What is the role of ammonium salts in the urine?
What is the role of ammonium salts in the urine?
What is the primary role of the urea cycle?
What is the primary role of the urea cycle?
What is the main source of ammonium for the urea cycle?
What is the main source of ammonium for the urea cycle?
What is the consequence of high levels of ammonia in the blood?
What is the consequence of high levels of ammonia in the blood?
Why is free ammonia not directly transported from peripheral tissues to the liver?
Why is free ammonia not directly transported from peripheral tissues to the liver?
What role does the urea cycle play in ammonia detoxification?
What role does the urea cycle play in ammonia detoxification?