Biochemical Pathways Quiz
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Questions and Answers

Which receptor is activated by epinephrine to stimulate liver phosphorylase kinase?

  • α-adrenergic receptor (correct)
  • δ-adrenergic receptor
  • γ-adrenergic receptor
  • β-adrenergic receptor

    • What is the role of phospholipids in the activation of liver phosphorylase kinase?

  • They bind to calmodulin to activate the kinase
  • They activate the kinase directly
  • They result in the movement of Ca2+ from the cytoplasm to the ER
  • They result in the movement of Ca2+ from the ER into the cytoplasm (correct)

    • Which protein is responsible for binding to Ca2+ and activating muscle phosphorylase kinase?

  • Phospholipid
  • G protein
  • PKA
  • Calmodulin (correct)

    • What triggers the release of acetylcholine at a neuromuscular junction to activate muscle phosphorylase kinase?

    <p>Release of Ca2+ from the sarcoplasmic reticulum</p> Signup and view all the answers

    What is the mechanism of activation for muscle phosphorylase kinase?

    <p>Binding of Ca2+-calmodulin complex</p> Signup and view all the answers

    Which of the following is not required for the activation of muscle phosphorylase kinase?

    <p>Phosphorylation by PKA</p> Signup and view all the answers

    What is the role of PKA in the activation of liver phosphorylase kinase?

    <p>It is not involved in the activation of liver phosphorylase kinase</p> Signup and view all the answers

    Which of the following is activated by Ca2+-calmodulin complex?

    <p>Muscle phosphorylase kinase</p> Signup and view all the answers

    Which of the following is not involved in the activation of muscle phosphorylase kinase?

    <p>PKA</p> Signup and view all the answers

    Which of the following is not a result of the activation of liver phosphorylase kinase?

    <p>Increase in insulin secretion</p> Signup and view all the answers

    Which receptor is activated by epinephrine to stimulate liver phosphorylase kinase?

    <p>α-adrenergic receptor</p> Signup and view all the answers

    What is the role of phospholipids in the activation of liver phosphorylase kinase?

    <p>They result in the movement of Ca2+ from the ER into the cytoplasm</p> Signup and view all the answers

    Which protein is responsible for binding to Ca2+ and activating muscle phosphorylase kinase?

    <p>Calmodulin</p> Signup and view all the answers

    What triggers the release of acetylcholine at a neuromuscular junction to activate muscle phosphorylase kinase?

    <p>Release of Ca2+ from the sarcoplasmic reticulum</p> Signup and view all the answers

    What is the mechanism of activation for muscle phosphorylase kinase?

    <p>Binding of Ca2+-calmodulin complex</p> Signup and view all the answers

    Which of the following is not required for the activation of muscle phosphorylase kinase?

    <p>Phosphorylation by PKA</p> Signup and view all the answers

    What is the role of PKA in the activation of liver phosphorylase kinase?

    <p>It is not involved in the activation of liver phosphorylase kinase</p> Signup and view all the answers

    Which of the following is not activated by Ca2+-calmodulin complex?

    <p>PKA</p> Signup and view all the answers

    Which of the following is not involved in the activation of muscle phosphorylase kinase?

    <p>PKA</p> Signup and view all the answers

    Which of the following is not a result of the activation of liver phosphorylase kinase?

    <p>Increase in insulin secretion</p> Signup and view all the answers

    Which molecule is responsible for the activation of liver phosphorylase kinase?

    <p>Epinephrine</p> Signup and view all the answers

    What is the role of acetylcholine in the activation of muscle phosphorylase kinase?

    <p>Binds to sarcoplasmic Ca2+</p> Signup and view all the answers

    What is the difference between the activation of liver and muscle phosphorylase kinase?

    <p>Liver phosphorylase kinase is activated by acetylcholine, while muscle phosphorylase kinase is activated by epinephrine</p> Signup and view all the answers

    What is the function of phosphorylase kinase?

    <p>Activates glycogen phosphorylase</p> Signup and view all the answers

    How does Ca2+ activate muscle phosphorylase kinase?

    <p>Binds to calmodulin</p> Signup and view all the answers

    What is the source of Ca2+ for the activation of liver phosphorylase kinase?

    <p>Endoplasmic reticulum</p> Signup and view all the answers

    What is the role of calmodulin in the activation of muscle phosphorylase kinase?

    <p>Activates the kinase</p> Signup and view all the answers

    What is the role of PKA in the activation of muscle phosphorylase kinase?

    <p>Phosphorylates the kinase</p> Signup and view all the answers

    What is the end result of the activation of phosphorylase kinase?

    <p>Breakdown of glycogen</p> Signup and view all the answers

    What is the difference between the activation of liver and muscle phosphorylase kinase in terms of the need for phosphorylation?

    <p>Liver phosphorylase kinase needs to be phosphorylated by PKA, while muscle phosphorylase kinase does not</p> Signup and view all the answers

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