BIO411 Genome Regulation: Cytoplasmic Determinants
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Questions and Answers

What is the function of cytoplasmic determinants in an unfertilized egg?

  • They are responsible for fertilization
  • They produce tissue-specific proteins
  • They determine the sex of the offspring
  • They influence early development (correct)
  • What is the result of cells containing different cytoplasmic determinants after zygote mitosis?

  • Stem cell formation
  • Different gene expression (correct)
  • Uniform gene expression
  • Cell death
  • What is the process called when signal molecules from embryonic cells cause transcriptional changes in nearby target cells?

  • Determination
  • Differentiation
  • Induction (correct)
  • Pattern formation
  • What is the sequence of events in cellular differentiation?

    <p>Determination precedes differentiation</p> Signup and view all the answers

    What is the development of a spatial organization of tissues and organs called?

    <p>Pattern formation</p> Signup and view all the answers

    What is positional information responsible for in pattern formation?

    <p>Telling a cell its location relative to the body axes</p> Signup and view all the answers

    What determines the axes in Drosophila before fertilization?

    <p>Cytoplasmic determinants</p> Signup and view all the answers

    What is the stage of development that follows fertilization in Drosophila?

    <p>Segmented larva with three larval stages</p> Signup and view all the answers

    Study Notes

    Cytoplasmic Determinants and Inductive Signals

    • Egg cytoplasm contains RNA, proteins, and other substances distributed unevenly, influencing early development.
    • Cytoplasmic determinants are maternal substances in the egg that influence early development.
    • As the zygote divides by mitosis, cells contain different cytoplasmic determinants, leading to different gene expression.
    • The environment around the cell, especially signals from nearby embryonic cells, provides developmental information.
    • Induction: signal molecules from embryonic cells cause transcriptional changes in nearby target cells, inducing differentiation of specialized cell types.

    Sequential Regulation of Gene Expression

    • Determination commits a cell to its final fate.
    • Determination precedes differentiation.
    • Cell differentiation is marked by the production of tissue-specific proteins.

    Pattern Formation: Setting Up the Body Plan

    • Pattern formation is the development of a spatial organization of tissues and organs.
    • In animals, pattern formation begins with the establishment of the major axes.
    • Positional information provides molecular cues that control pattern formation, telling a cell its location relative to the body axes and neighboring cells.

    The Life Cycle of Drosophila

    • Cytoplasmic determinants in the unfertilized Drosophila egg determine the axes before fertilization.
    • After fertilization, the embryo develops into a segmented larva with three larval stages.

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    Description

    This quiz covers the concept of cytoplasmic determinants and inductive signals in genome regulation, specifically in the context of maternal substances in unfertilized eggs.

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