Week 1 inflammation

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30 Questions

What is the main cause of atherosclerosis?

Chronic inflammation of vessel wall

What is the connection between diabetes and inflammation?

Diabetes promotes oxidative stress which enhances inflammation

What is the link between visceral fat and inflammation?

Visceral fat contains proinflammatory cytokines which cause low-grade inflammation

Which type of immune response takes more time to develop and can become maladaptive in autoimmune conditions?

Adaptive immune response

What are the cardinal features of acute inflammation?

Vascular changes, pain and dysfunction, classic inflammatory cells

Which type of arthritis is marked by systemic inflammation caused by the immune system attacking healthy tissue?

Rheumatoid arthritis

Which of the following may trigger inflammation?

Exposure to UV light

What is the difference between acute and chronic inflammation?

Acute inflammation commences within minutes and dissipates within few hours to days, while chronic inflammation may linger for months to years

What are some factors that can influence soft tissue healing?

Getting enough rest

Which type of nerve injury involves division of entire nerve, Wallerian degeneration, and limited regeneration due to intraneural damage and misdirected regeneration?

Neurotmesis

What is the recommended treatment for acute inflammation and tissue injury?

Ice, compression, and elevation

What are the features of chronic tendinopathy?

Tissue destruction and attempts at healing

Which of the following is NOT a major factor that influences muscle healing?

Limited early stress across the wound

What is the difference between a grade I and a grade II muscle strain?

Grade I has minimal haematoma, while Grade II has greater haematoma

What is the main factor that influences ligament healing?

Gap between ligament ends

What is the purpose of the inflammatory phase in soft-tissue healing?

To eliminate debris

What is the difference between CRP and hs-CRP?

CRP is used to measure risk of heart disease and stroke, while hs-CRP is the most widely used lab measure of inflammation

What is the purpose of the proliferative phase in soft-tissue healing?

To generate new replacement tissue or scar tissue

What is the time frame for muscle soreness in Delayed Onset Muscle Soreness (DOMS)?

Starts after 24 hrs, peaks at 24-48 hrs and subsides by 7 days

What is the main cause of tendon injury?

Chronic overload and microdamage

What are the symptoms of compartment syndrome?

Swollen, painful limb, tense muscle, weak pulse or diminished nerve function

Which of the following is a first-line treatment for rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis?

Disease-modifying anti-rheumatic drugs (DMARDs)

Which of the following is a way that exercise promotes tissue repair?

Promoting release of anti-inflammatory proteins

What are the detrimental effects of immobilisation after a ligament injury?

Increased resorption of bone

Which of the following can eliminate or reduce the need for NSAIDs or steroids?

DMARDs

What do disease-modifying anti-rheumatic drugs (DMARDs) do?

Suppress inflammation

Which of the following can assist in weight loss?

Exercise

What is the effect of exercise on inflammation-promoting macrophages in fat tissue?

It decreases their proliferation

What is the first-line treatment for rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis?

DMARDs

What effect does immobilisation have on bone resorption?

It increases bone resorption

Test your knowledge on biceps chronic tendinopathy with this quiz. Learn about the features of chronic inflammation, tissue destruction, and attempts at healing, as well as the changes in tendon structure and mechanical properties. Keywords: biceps, tendinopathy, chronic inflammation, tissue destruction, neovessels, fibrosis.

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