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Questions and Answers
Which of the following physiological systems is NOT directly influenced by exercise?
Which of the following physiological systems is NOT directly influenced by exercise?
During the inflammatory phase of tissue healing, which of the following is a primary goal of exercise prescription?
During the inflammatory phase of tissue healing, which of the following is a primary goal of exercise prescription?
What is the primary role of the endocrine system during exercise?
What is the primary role of the endocrine system during exercise?
Which of the following tissue healing phases is characterized by the formation of new collagen fibers?
Which of the following tissue healing phases is characterized by the formation of new collagen fibers?
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How does exercise impact the cardiovascular system during the remodeling phase of tissue healing?
How does exercise impact the cardiovascular system during the remodeling phase of tissue healing?
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What is the primary function of the Krebs Cycle?
What is the primary function of the Krebs Cycle?
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What is the role of oxygen in aerobic ATP production?
What is the role of oxygen in aerobic ATP production?
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How many molecules of ATP are produced directly in the Krebs Cycle?
How many molecules of ATP are produced directly in the Krebs Cycle?
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Which of these statements is TRUE about the citric acid cycle?
Which of these statements is TRUE about the citric acid cycle?
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What is the net gain of NADH molecules produced in one complete turn of the Krebs Cycle?
What is the net gain of NADH molecules produced in one complete turn of the Krebs Cycle?
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A client reports experiencing fatigue and muscle weakness, particularly during high-intensity activities, and notes difficulty recovering between exercise bouts. Which metabolic system is most likely compromised in this scenario?
A client reports experiencing fatigue and muscle weakness, particularly during high-intensity activities, and notes difficulty recovering between exercise bouts. Which metabolic system is most likely compromised in this scenario?
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Which of the following is NOT a characteristic of impaired glycolysis?
Which of the following is NOT a characteristic of impaired glycolysis?
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A client presents with severe fatigue, muscle weakness, exercise intolerance, and organ dysfunction. These symptoms strongly suggest a dysfunction in which energy system?
A client presents with severe fatigue, muscle weakness, exercise intolerance, and organ dysfunction. These symptoms strongly suggest a dysfunction in which energy system?
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Which of the following is a key characteristic that distinguishes the inflammatory phase of tissue healing from the proliferation phase?
Which of the following is a key characteristic that distinguishes the inflammatory phase of tissue healing from the proliferation phase?
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A client is engaging in a marathon run. Which of the following statements is ACCURATE regarding their energy system usage during the event?
A client is engaging in a marathon run. Which of the following statements is ACCURATE regarding their energy system usage during the event?
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Which of these factors is NOT a direct contributor to impaired glycolysis?
Which of these factors is NOT a direct contributor to impaired glycolysis?
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A client reports that simple tasks feel exhausting. This symptom could be attributed to a dysfunction in which energy system?
A client reports that simple tasks feel exhausting. This symptom could be attributed to a dysfunction in which energy system?
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Which of the following is NOT a characteristic of the remodeling phase of tissue healing?
Which of the following is NOT a characteristic of the remodeling phase of tissue healing?
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What is the primary function of platelets during the hemostasis phase of tissue healing?
What is the primary function of platelets during the hemostasis phase of tissue healing?
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A client complains of exercise intolerance and reports experiencing early fatigue during training. This is likely associated with a disruption in which of the following?
A client complains of exercise intolerance and reports experiencing early fatigue during training. This is likely associated with a disruption in which of the following?
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What is the primary role of the Krebs cycle?
What is the primary role of the Krebs cycle?
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What is the main source of energy for high-intensity exercise lasting 5-6 seconds?
What is the main source of energy for high-intensity exercise lasting 5-6 seconds?
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Which of the following is NOT a substrate involved in bioenergetic reactions?
Which of the following is NOT a substrate involved in bioenergetic reactions?
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What is the main function of the electron transport chain?
What is the main function of the electron transport chain?
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What is the name of the process by which ATP is produced in the electron transport chain?
What is the name of the process by which ATP is produced in the electron transport chain?
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Which energy system contributes the most to a marathon runner's energy needs?
Which energy system contributes the most to a marathon runner's energy needs?
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What is the major function of neutrophils in acute inflammation?
What is the major function of neutrophils in acute inflammation?
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How does exercise affect the concentration of glycogen in muscle and liver?
How does exercise affect the concentration of glycogen in muscle and liver?
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Which of the following is NOT a factor that can impede healing?
Which of the following is NOT a factor that can impede healing?
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What is the primary goal of physical therapy during the acute stage of inflammation?
What is the primary goal of physical therapy during the acute stage of inflammation?
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What is the main difference between acute and chronic inflammation?
What is the main difference between acute and chronic inflammation?
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What is the term used for the anaerobic contribution to energy production at the start of exercise?
What is the term used for the anaerobic contribution to energy production at the start of exercise?
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What is the significance of the oxygen uptake reaching a "steady state" during low-intensity exercise?
What is the significance of the oxygen uptake reaching a "steady state" during low-intensity exercise?
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Which of the following is NOT a characteristic of the fibroblastic-repair phase?
Which of the following is NOT a characteristic of the fibroblastic-repair phase?
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Which of the following is a correct statement about the relationship between inflammation and healing?
Which of the following is a correct statement about the relationship between inflammation and healing?
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Which of the following is NOT a component of the phosphagen system?
Which of the following is NOT a component of the phosphagen system?
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What is the primary function of the oxidative system?
What is the primary function of the oxidative system?
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Which of the following statements about lactate is FALSE?
Which of the following statements about lactate is FALSE?
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What is the primary energy source used during high-intensity, short-duration activities, like a 100-meter sprint?
What is the primary energy source used during high-intensity, short-duration activities, like a 100-meter sprint?
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Which of the following is NOT a characteristic of the glycolytic system?
Which of the following is NOT a characteristic of the glycolytic system?
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What is the role of ATPase in ATP hydrolysis?
What is the role of ATPase in ATP hydrolysis?
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Which of the following accurately describes the relationship between the phosphagen system and glycogen stores?
Which of the following accurately describes the relationship between the phosphagen system and glycogen stores?
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The rate of glycolysis is influenced by several factors. Which of the following would DECREASE the rate of glycolysis?
The rate of glycolysis is influenced by several factors. Which of the following would DECREASE the rate of glycolysis?
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Which of the following statements about the lactate threshold is TRUE?
Which of the following statements about the lactate threshold is TRUE?
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What is the primary energy source used during prolonged, submaximal exercise, such as a long distance run?
What is the primary energy source used during prolonged, submaximal exercise, such as a long distance run?
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Which enzyme is directly involved in the phosphagen system's rapid replenishment of ATP?
Which enzyme is directly involved in the phosphagen system's rapid replenishment of ATP?
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What is the primary function of the NADH and FADH2 molecules produced during the oxidative system?
What is the primary function of the NADH and FADH2 molecules produced during the oxidative system?
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Which of the following is a primary energy source used at rest?
Which of the following is a primary energy source used at rest?
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What is the difference between active and passive mobility?
What is the difference between active and passive mobility?
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Which of the following best describes the concept of neuromuscular control?
Which of the following best describes the concept of neuromuscular control?
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Flashcards
Physiologic Processes
Physiologic Processes
Changes in body systems during exercise including endocrine, cardiovascular, pulmonary, and neuromusculoskeletal.
Endocrine System
Endocrine System
A system that regulates hormones impacting metabolism and energy during exercise.
Tissue Healing Phases
Tissue Healing Phases
Stages of recovery following injury: inflammation, repair, and remodeling.
Exercise Prescription
Exercise Prescription
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Cardiovascular System Impact
Cardiovascular System Impact
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Krebs Cycle
Krebs Cycle
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Electron Transport Chain
Electron Transport Chain
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Oxidative Phosphorylation
Oxidative Phosphorylation
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Acetyl CoA
Acetyl CoA
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Energy Carriers in Krebs Cycle
Energy Carriers in Krebs Cycle
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Therapeutic Interventions
Therapeutic Interventions
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Muscle Performance
Muscle Performance
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Mobility
Mobility
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Hydrolysis of ATP
Hydrolysis of ATP
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Phosphagen System
Phosphagen System
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Glycolysis
Glycolysis
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Energy Investment Phase
Energy Investment Phase
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Lactate Threshold
Lactate Threshold
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Oxidative System
Oxidative System
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ATP Regeneration
ATP Regeneration
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Type II Muscle Fibers
Type II Muscle Fibers
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Biochemical Pathways
Biochemical Pathways
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Substrate-Level Phosphorylation
Substrate-Level Phosphorylation
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Passive vs Active Mobility
Passive vs Active Mobility
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Lactate Accumulation
Lactate Accumulation
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Fibroblasts
Fibroblasts
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Acute Inflammation Signs
Acute Inflammation Signs
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Beta Oxidation
Beta Oxidation
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Delayed Recovery
Delayed Recovery
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Acetyl CoA Production
Acetyl CoA Production
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Krebs Cycle Energy Yield
Krebs Cycle Energy Yield
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GTP Function
GTP Function
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Electron Transport Chain Role
Electron Transport Chain Role
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ATP Production from NADH
ATP Production from NADH
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Beta-Oxidation Process
Beta-Oxidation Process
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Glycogen vs Glucose
Glycogen vs Glucose
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Fatigue and Substrate Depletion
Fatigue and Substrate Depletion
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Repletion of Muscle Glycogen
Repletion of Muscle Glycogen
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Oxygen Uptake Definition
Oxygen Uptake Definition
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Inflammatory Response Sequence
Inflammatory Response Sequence
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Fibroblastic-Repair Phase
Fibroblastic-Repair Phase
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Chronic Inflammation Characteristics
Chronic Inflammation Characteristics
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Factors Impeding Healing
Factors Impeding Healing
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Study Notes
Therapeutic Interventions - Week 1
- Therapeutic interventions aim to improve, restore, or enhance function, remediate or prevent impairments, and prevent or reduce health risk factors.
- Function depends on balance, stability, neuromuscular control, muscle performance, cardiopulmonary endurance, mobility, and flexibility.
- Passive mobility relies on soft tissue extensibility.
- Active mobility involves neuromuscular activation.
- Bioenergetics deals with energy production in exercise.
Bioenergetics and ATP
- ATP (adenosine triphosphate) powers muscular activity.
- ATP is a high-energy molecule storing energy in its phosphate bonds.
- ATP hydrolysis (breakdown) releases energy.
- Muscle cells have limited ATP stores, requiring continuous replenishment via three energy systems:
- Phosphagen
- Glycolytic
- Oxidative
Phosphagen System
- Provides ATP quickly for short, high-intensity activities.
- Active at the start of all exercise.
- Involves the donation of a phosphate group from phosphocreatine(PCr) to ADP to form ATP.
- The creatine kinase reaction is crucial.
- Limited by creatine phosphate stores.
- Type II muscle fibers have higher creatine phosphate concentrations.
Glycolysis
- Breakdown of carbohydrates to synthesize ATP.
- Anaerobic pathway.
- Glycolysis can occur in the fast or slow pathway.
- Considered anaerobic. Higher capacity than phosphagen system for activities lasting 30 seconds to 2–3 minutes.
- Forms pyruvate (or lactate) from glucose or glycogen.
- Yields a net 2 ATP (or 3 ATP from glycogen).
- The rate is controlled by allosteric regulation, primarily by phosphofructokinase.
Lactate Threshold
- The exercise intensity where blood lactate rises abruptly above baseline.
- Represents increased anaerobic energy production.
- Typically begins at 50-60% maximal oxygen uptake for untrained individuals.
Oxidative System
- Aerobic pathway utilizing carbohydrates (initially), fats, and proteins, for energy that is dominant during prolonged, low-intensity exercise.
- Involves the Krebs cycle and electron transport chain in the mitochondria.
- Produces large amounts of ATP from complete oxidation.
- The Krebs cycle (Citric Acid Cycle) generates energy carriers NADH and FADH2 from acetyl-CoA.
- Electron transport chain (oxidative phosphorylation) uses NADH and FADH2 to produce massive amounts of ATP.
- 38 ATP are produced at the end of this process from the degradation of 1 glucose molecule. Muscle glycogen starts with 39 ATP.
Fat and Protein Oxidation
- Fats are oxidized via beta-oxidation, forming acetyl-CoA.
- Proteins are broken down into amino acids and converted to glucose (gluconeogenesis).
Energy Capacity
- Exercise intensity determines the dominant energy system (phosphagen, glycolytic, oxidative).
- Substrate depletion (e.g., glycogen) can limit exercise performance.
- Replenishment of energy substrates can take time.
Oxygen Uptake
- Oxygen uptake increases during exercise to meet the increased energy demand.
- An oxygen deficit occurs at the start of exercise.
- Excess post-exercise oxygen consumption (EPOC) is the elevated oxygen uptake after exercise.
Inflammation and Tissue Healing
- Tissue healing involves three phases:
- Inflammatory
- Fibroblastic repair (proliferative)
- Maturation/remodeling
- Inflammation involves redness, warmth, pain, swelling, and loss of function.
- Hemostasis (stopping bleeding) occurs first.
- Neutrophils and macrophages clear debris.
- Fibroblasts lay down collagen and elastin.
- Collagen realignment occurs during remodeling (typically takes a long time - up to years).
Exercise Prescription During Healing Phases
- Acute: Protect (RICE - rest, ice, compression, elevation), passive range of motion, non-destructive movements.
- Subacute/Proliferative: Controlled motion, selective stretching and progressive mobilization. Promote healing with gradually increasing strength, muscular endurance, and cardiopulmonary exercises.
- Chronic: Minimal to no protection, progressive strengthening, functional exercises.
Factors Impeding Healing
- Injury severity, edema, hemorrhage, poor vasculature, tissue separation, muscle spasm, atrophy, corticosteroids, infection, poor nutrition, and age.
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Description
This quiz covers the fundamentals of therapeutic interventions, focusing on how various modalities aim to enhance physical function and address health risks. It includes topics on mobility, bioenergetics, and the role of ATP in muscle performance. Test your understanding of these critical concepts in physical therapy and exercise science.