20 Questions
Which cell surface marker is associated with BIA-ALCL?
CD30
What type of lymphoma is BIA-ALCL?
T-cell lymphoma
Which type of graft offers superior osteogenesis, osteoinduction, and graft take in comparison with cortical grafts and allografts?
Cancellous bone grafts
What factor is most associated with high risk for recurrence of basal cell carcinoma?
Perineural involvement
What is the primary reason for using allografts in reconstructing highly complex defects?
No donor site morbidity
Which of the following factors is NOT associated with a high risk for recurrence of squamous cell carcinoma?
Adenoid subtype
Which of the following flaps for breast reconstruction does NOT involve the harvest of significant abdominal muscle?
Superficial inferior epigastric artery (SIEA) flap
Which treatment option has been shown to be extremely effective in treating venous and lymphatic malformations, as well as vascular tumors associated with Kasabach-Merritt phenomenon?
Systemic sirolimus therapy
Which condition is NOT a differential diagnosis for juvenile breast hypertrophy?
Carcinoma
Which treatment option is indicated for mastodynia, neck/back pain secondary to large size, difficulty with clothing due to asymmetry, and to alleviate patient concern?
Reduction mammoplasty
Which cell surface marker is NOT associated with BIA-ALCL?
CD45
Which type of lymphoma is BIA-ALCL?
T-cell lymphoma
What factor is most associated with high risk for recurrence of basal cell carcinoma?
Perineural involvement
Which treatment option is indicated for mastodynia, neck/back pain secondary to large size, difficulty with clothing due to asymmetry, and to alleviate patient concern?
Breast reduction
Which of the following factors is NOT associated with a high risk for recurrence of squamous cell carcinoma?
Perineural involvement
Which of the following factors is NOT associated with a high risk for recurrence of squamous cell carcinoma?
Well differentiation
Which type of flap for breast reconstruction does NOT involve the harvest of significant abdominal muscle?
Superficial inferior epigastric artery (SIEA) flap
Which treatment option is NOT effective in treating venous and lymphatic malformations, as well as vascular tumors associated with Kasabach-Merritt phenomenon?
Propranolol therapy
Which of the following is NOT a differential diagnosis for juvenile breast hypertrophy?
Carcinoma
Which treatment option is indicated for mastodynia, neck/back pain secondary to large size, difficulty with clothing due to asymmetry, and to alleviate patient concern?
Reduction mammoplasty
Study Notes
Medical Facts and Considerations
- Large cell lymphoma (BIA-ALCL) is associated with textured implants and can be diagnosed using ultrasound and the detection of CD30 cell surface marker.
- Intercalary allografts are commonly used for reconstructing large defects of the femur and tibia due to their high mechanical strength.
- In breast reconstruction, the superficial inferior epigastric artery (SIEA) flap is the only option that does not violate the abdominal fascia, while other flaps may lead to abdominal bulge or hernia formation.
- Perineural involvement is a high-risk factor for recurrence of basal cell carcinoma, along with other factors such as poorly defined borders, recurrent lesions, and aggressive histologic subtypes.
- Sirolimus therapy has shown effectiveness in reducing the size of venous and lymphatic malformations, as well as treating vascular tumors associated with Kasabach-Merritt phenomenon.
- Reduction mammoplasty is the treatment for juvenile breast hypertrophy, which is characterized by diffuse breast enlargement without discrete masses or nodularity.
- Phyllodes tumors, large benign tumors, typically occur in perimenopausal patients and are histologically distinct from fibroadenomas.
- Cancellous bone grafts offer superior osteogenesis, osteoinduction, and graft take compared to cortical grafts and allografts.
- Cost is not a significant consideration in reconstructing complex bone defects.
- In breast reconstruction, the use of muscle-sparing free TRAMs or DIEPs may have different effects on abdominal wall morbidity.
- Systemic sirolimus therapy is an effective and reasonable treatment option for venous and lymphatic malformations, as well as vascular tumors associated with Kasabach-Merritt phenomenon.
- Surgical excision is not a suitable option for diffuse and complex diseases due to location and potential damage to surrounding structures.
Test your knowledge on the diagnosis of BIA-ALCL, a type of T-cell lymphoma associated with textured implants. Learn about the cell surface markers, ultrasound diagnosis, and the role of CD30 and ALK in this condition. Take this quiz to assess your understanding of BIA-ALCL diagnosis.
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