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Beta-Lactam Antibiotic Prescription in Norway (2015)

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8 Questions

What was the approximate DDD/1000 inhabitants/day for beta-lactam prescriptions in Norway in 2015?

10.2

Which beta-lactam had the highest DDD value among the listed agents in Norway in 2015?

flucloxacillin

Which two beta-lactams had the same DDD value of 2.32?

phenoxymethylpenicillin and benzathine penicillin

What percentage of beta-lactam parenteral prescriptions were discharged from Molde Hospital?

20.8%

According to Huttner and colleagues, how much lower was the outpatient consumption of amoxicillin compared to penicillin?

6.5-fold

What percentage of total antibiotic prescriptions did beta-lactams constitute according to Huttner's study?

50%

Which combination beta-lactam was found to be 3.2-fold higher in use than amoxicillin?

amoxicillin/clavulanic acid

Which beta-lactam had the lowest DDD value among the agents listed?

ampicillin with colestyramine

Study Notes

Beta-Lactam Antibiotics in Norway

  • In 2015, the average consumption of beta-lactam antibiotics in Norway was 10.2 DDD/1000 inhabitants/day.
  • The individual DDD values for different beta-lactam agents were: amoxicillin (2.71), amoxicillin/clavulanic acid (1.32), phenoxymethylpenicillin (2.32), and flucloxacillin (3.59).

Age-Specific Consumption

  • Children under the age of ten accounted for one-third of all beta-lactam antibiotics dispensed in outpatient settings.
  • Consumption rates of beta-lactam antibiotics decreased significantly among children above the age of ten.

Hospital Prescriptions

  • Few parenteral prescriptions were discharged from hospitals: 3.4% from St Olav's Hospital and 20.8% from Molde Hospital.

International Variability

  • Beta-lactam antibiotic usage varies greatly between different countries and regions, depending on local prescribing habits, regional antibiotic resistance rates, and community-specific microbiomes.

Amoxicillin and Amoxiclav Consumption

  • Outpatient consumption of amoxicillin was found to be 6.5-fold lower than that of penicillin.
  • Amoxicillin/clavulanic acid (amoxiclav) was the most popular beta-lactam combination, with usage 3.2-fold higher than that of amoxicillin.

Beta-Lactam Prescription Patterns

  • Beta-lactams constituted an average of 50% of all antibiotic prescriptions.
  • The most commonly used beta-lactams were amoxicillin (73.2%), amoxicillin/clavulanic acid (10.4%), and benzathine penicillin (10.4%).

This quiz is about the prescription rates of beta-lactam antibiotics in Norway in 2015, including the individual Defined Daily Doses (DDD) for different agents. It provides information on the average DDD per 1000 inhabitants per day.

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