Beta Blockers Dosing and Effects Quiz
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Questions and Answers

What is the goal when titrating propranolol or nadolol for varices prophylaxis?

  • Taper down the dose until no longer tolerated
  • Reach a 20-25% reduction in resting HR (correct)
  • Maintain an absolute HR of 80-90 beats/min
  • Achieve a resting HR of 70-75 beats/min
  • Which of the following is NOT a reason for using nonselective ß-blockers in patients with varices at high risk for bleeding?

  • Promote splanchnic vasoconstriction
  • Enhance hepatic vein pressure (correct)
  • Decrease cardiac output
  • Prevent splanchnic vasodilation
  • What is the preferred pharmacologic agent for the treatment of bleeding varices?

  • Vasopressin
  • Nitroglycerin
  • Somatostatin
  • Octreotide (correct)
  • What is the maximum duration that vasopressin should be infused for in the treatment of variceal bleeding?

    <p>24 hours</p> Signup and view all the answers

    In patients with ascites or infection, which antibiotic is commonly used to decrease mortality?

    <p>Ceftriaxone</p> Signup and view all the answers

    What is the primary prophylactic treatment for varices in patients at high risk for bleeding?

    <p>eta-blockers</p> Signup and view all the answers

    When considering secondary prophylaxis for varices, what should be the target heart rate during propranolol or nadolol treatment?

    <p>55-60 beats/min</p> Signup and view all the answers

    What is the primary mechanism of action of beta blockers, such as propranolol, in the management of portal hypertension and varices?

    <p>Decrease cardiac output</p> Signup and view all the answers

    Why is it essential to measure the pressure gradient between the portal vein and inferior vena cava (IVC) for diagnosis of portal hypertension?

    <p>To assess the resistance to blood flow in the portal vein</p> Signup and view all the answers

    Which of the following is a non-pharmacologic management strategy for portal hypertension and varices?

    <p>Dietary sodium restriction</p> Signup and view all the answers

    What is the primary goal of endoscopic treatment in patients with esophageal and gastric varices?

    <p>Reduce bleeding risk from varices</p> Signup and view all the answers

    In patients with ascites, which of the following antibiotics is commonly used for primary prophylaxis against spontaneous bacterial peritonitis?

    <p>Ciprofloxacin</p> Signup and view all the answers

    Which of the following medications is commonly used in combination with vasoconstrictors for acute variceal bleeding?

    <p>Nitroglycerin</p> Signup and view all the answers

    When titrating the dosage of nadolol in the management of varices, what is a common guideline regarding dosing adjustments?

    <p>Titrate up if heart rate decreases by 5 beats per minute or more</p> Signup and view all the answers

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