Beta Blockers Dosing and Effects Quiz

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Questions and Answers

What is the goal when titrating propranolol or nadolol for varices prophylaxis?

  • Taper down the dose until no longer tolerated
  • Reach a 20-25% reduction in resting HR (correct)
  • Maintain an absolute HR of 80-90 beats/min
  • Achieve a resting HR of 70-75 beats/min

Which of the following is NOT a reason for using nonselective ß-blockers in patients with varices at high risk for bleeding?

  • Promote splanchnic vasoconstriction
  • Enhance hepatic vein pressure (correct)
  • Decrease cardiac output
  • Prevent splanchnic vasodilation

What is the preferred pharmacologic agent for the treatment of bleeding varices?

  • Vasopressin
  • Nitroglycerin
  • Somatostatin
  • Octreotide (correct)

What is the maximum duration that vasopressin should be infused for in the treatment of variceal bleeding?

<p>24 hours (D)</p> Signup and view all the answers

In patients with ascites or infection, which antibiotic is commonly used to decrease mortality?

<p>Ceftriaxone (A)</p> Signup and view all the answers

What is the primary prophylactic treatment for varices in patients at high risk for bleeding?

<p>eta-blockers (B)</p> Signup and view all the answers

When considering secondary prophylaxis for varices, what should be the target heart rate during propranolol or nadolol treatment?

<p>55-60 beats/min (C)</p> Signup and view all the answers

What is the primary mechanism of action of beta blockers, such as propranolol, in the management of portal hypertension and varices?

<p>Decrease cardiac output (A)</p> Signup and view all the answers

Why is it essential to measure the pressure gradient between the portal vein and inferior vena cava (IVC) for diagnosis of portal hypertension?

<p>To assess the resistance to blood flow in the portal vein (D)</p> Signup and view all the answers

Which of the following is a non-pharmacologic management strategy for portal hypertension and varices?

<p>Dietary sodium restriction (C)</p> Signup and view all the answers

What is the primary goal of endoscopic treatment in patients with esophageal and gastric varices?

<p>Reduce bleeding risk from varices (C)</p> Signup and view all the answers

In patients with ascites, which of the following antibiotics is commonly used for primary prophylaxis against spontaneous bacterial peritonitis?

<p>Ciprofloxacin (D)</p> Signup and view all the answers

Which of the following medications is commonly used in combination with vasoconstrictors for acute variceal bleeding?

<p>Nitroglycerin (B)</p> Signup and view all the answers

When titrating the dosage of nadolol in the management of varices, what is a common guideline regarding dosing adjustments?

<p>Titrate up if heart rate decreases by 5 beats per minute or more (C)</p> Signup and view all the answers

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