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Questions and Answers
What is a desired effect of beta-specific adrenergic agonists?
What is a desired effect of beta-specific adrenergic agonists?
- Uterine contraction
- Bronchodilation (correct)
- Decreased blood flow to skeletal muscles
- Decreased heart rate
Which of the following is an indication for using beta-specific adrenergic agonists?
Which of the following is an indication for using beta-specific adrenergic agonists?
- Hypokalemia
- Hypotension
- COPD (correct)
- Bradycardia
How do beta-specific adrenergic agonists lower potassium levels?
How do beta-specific adrenergic agonists lower potassium levels?
- By blocking potassium channels
- By inhibiting the N+/K+ pump
- By increasing potassium excretion in the kidneys
- By shifting potassium into cells via the N+/K+ pump (correct)
Which medication is selective for B-2 adrenergic receptors?
Which medication is selective for B-2 adrenergic receptors?
What is a contraindication for the use of beta-specific adrenergic agonists?
What is a contraindication for the use of beta-specific adrenergic agonists?
Which of the following conditions requires caution when using beta-specific adrenergic agonists?
Which of the following conditions requires caution when using beta-specific adrenergic agonists?
Which of the following is a non-selective beta-adrenergic agonist?
Which of the following is a non-selective beta-adrenergic agonist?
What effect do beta-2 agonists have on the uterus?
What effect do beta-2 agonists have on the uterus?
In what situation might non-selective Isoproterenol be indicated?
In what situation might non-selective Isoproterenol be indicated?
A patient with which of the following should avoid beta-specific adrenergic agonists?
A patient with which of the following should avoid beta-specific adrenergic agonists?
Flashcards
Beta-Specific Adrenergic Agonists
Beta-Specific Adrenergic Agonists
These drugs selectively stimulate beta-adrenergic receptors, leading to increased heart rate, bronchodilation, and vasodilation in skeletal muscles.
Indications for Beta-Specific Adrenergic Agonists
Indications for Beta-Specific Adrenergic Agonists
COPD, Asthma, Hyperkalemia (shifts potassium into cells)
Selective Beta-2 Agonists (Examples)
Selective Beta-2 Agonists (Examples)
Albuterol, arformoterol, formoterol, levalbuterol, metaproterenol, olodaterol, salmeterol, terbutaline
Isoproterenol (Non-Selective) uses
Isoproterenol (Non-Selective) uses
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Contraindications for Beta-Specific Adrenergic Agonists
Contraindications for Beta-Specific Adrenergic Agonists
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Cautions for Beta-Specific Adrenergic Agonists
Cautions for Beta-Specific Adrenergic Agonists
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Study Notes
Beta-Specific Adrenergic Agonists: Mechanism and Effects
- Selectively stimulates beta-adrenergic receptors.
- Increases heart rate, conductivity, and contractility.
- Causes bronchodilation.
- Increases blood flow to skeletal muscles and splanchnic beds.
- Relaxes the uterus.
Indications
- Used for COPD, asthma, and hyperkalemia.
- Shifts potassium into cells by activating the N+/K+ pump, lowering potassium levels in hyperkalemia.
Selective B-2 Agonists (EROL)
- Albuterol
- Arformoterol
- Formoterol
- Levalbuterol (Xopenex)
- Metaproterenol
- Olodaterol
- Salmeterol
- Terbutaline (IV)
Non-Selective Agonist
- Isoproterenol (IV) is non-selective.
- Used for shock with low cardiac output, cardiac arrest, and certain ventricular arrhythmias.
- Can treat heart block.
- Prevents bronchospasm during anesthesia.
- Treats acute hyperkalemia in a hospital setting, but use with caution.
Contraindications
- Pulmonary hypertension and tachyarrhythmias.
- Eclampsia.
- Uterine hemorrhage and intrauterine death.
- Contraindicated in pregnancy and lactation.
Cautions
- Use with caution in patients with diabetes, thyroid disease, vasomotor problems, heart disease, stroke, and severe renal impairment.
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