36 Questions
What is the potential of benzoyl peroxide (2.5-10%) in relation to tumor initiation and complete carcinogenesis?
It is not likely to possess tumor initiating or complete carcinogenic potential
What type of effects were observed in mouse skin exposed to organic peroxides?
Subchronic effects related to carcinogenic potential
What is the concentration range of benzoyl peroxide mentioned in the text?
5-10%
What is the first choice for treating acne?
Tetracycline
Why should oral antibiotics be used for the shortest time possible?
To prevent antibiotic resistance
What is recommended to be used along with oral antibiotics for treating acne?
Topical retinoids and benzoyl peroxide
What is the purpose of injecting a diluted corticosteroid into an inflamed acne cyst?
To treat the inflamed cyst and prevent scarring
What is the potential consequence of a rupturing acne cyst?
Scarring
When may a consultant consider using intralesional corticosteroid injection for an acne cyst?
When the cyst becomes severely inflamed
What is the primary benefit of intralesional steroid injection compared to topical steroids?
Bypassing the barrier of a thickened stratum corneum
What is the primary purpose of delivering corticosteroids intralesionally?
Treating dermal inflammatory processes directly
How do intralesional steroids differ from topical steroids in terms of skin thinning?
They reduce the chance of epidermal atrophy
What is the recommended total dose of intralesional triamcinolone per injection site?
0.1-0.2 mL per square centimeter of involved skin
Why should intralesional injections be intradermal and not subcutaneous?
To avoid causing a dent in the skin
How often can intralesional triamcinolone injections be repeated?
Every 4-8 weeks
Which of the following is a retinoid?
Tretinoin
What is the primary effect of retinoids on the skin?
Stimulate epithelial growth and rapid turnover of the horny layer
How do retinoids prevent the formation of comedones?
Prevent the closure of the pilosebaceous orifice
How do retinoids affect abnormal hyperproliferative keratinocytes?
They decrease the cohesiveness of the keratinocytes
What is the potential effect of retinoids on the formation of comedones?
They prevent the formation of comedones
In what way do retinoids modulate keratinocyte differentiation?
They modulate keratinocyte differentiation
Which of the following is a topical retinoid?
Adapalene
Which retinoid is commonly used for severe nodular acne?
Isotretinoin
Which retinoid is commonly used in the treatment of photoaging?
Tretinoin
Which of the following has been reported to promote improvements in the appearance of acne lesions?
Lactic acid
Which compound, complexed with quaternary ammonium salts, has been reported to promote improvements in the appearance of acne lesions?
N acetyl dl methionine
Which of the following acids has been reported to promote improvements in the appearance of acne lesions?
Glycolic acid
What is the long-term use of oral contraceptives commonly used for in the treatment of acne in women?
Suppressing overactive glands
What is the primary effect of oral contraceptives on acne in women?
Clearing up acne
How do oral contraceptives typically affect overactive glands in women with acne?
Suppressing overactive glands
What type of light is used in phototherapy for treating acne?
Blue and red light
Which therapy involves intense blue or violet light for treating acne?
Photodynamic therapy
Which of the following is not used for treating acne, as per the given text?
Heat therapy
At what age does acne of any severity usually remit spontaneously?
Early to mid 20s
Who is more likely to have acne into their 40s?
Women
What is the typical prognosis for acne after the early to mid 20s?
It usually remits spontaneously
Test your knowledge about the use of benzoyl peroxide for acne treatment and its carcinogenic potential based on research findings. Explore the relationship between benzoyl peroxide and its potential effects on carcinogenesis.
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