18 Questions
Why is the parenteral route preferred for certain drugs instead of oral administration?
Destruction by stomach acids leading to poor bioavailability
What is the main advantage of intravenous administration of drugs?
100% bioavailability
What are the characteristics of Class IV drugs according to the BCS Classification system?
Low permeability, low solubility, poor absorption, high variability
Give an example of a Class I drug based on BCS Classification.
Cimetidine
What are some common dosage forms for drug administration?
Tablets, capsules, pills, ointments, syrups, injections
What are the three main factors that determine the preferred route of drug administration?
Body part being treated, drug mechanism, solubility and permeability of the drug
What is the main problem with conventional drug delivery systems?
Poor bioavailability and fluctuations in plasma drug level.
Why are controlled drug delivery systems developed?
To combat the problems associated with conventional drug delivery.
What is the key objective of controlled drug delivery systems?
To achieve sustained release and deliver the drug at a controlled rate to the target site.
What has been the focus of the evolution in controlled drug delivery systems in the past two decades?
Ranging from macro scale to nano scale and intelligent targeted delivery.
In drug delivery systems, what aspect does the review emphasize on as a fundamental understanding?
Pharmacokinetics of the drug.
What renders the whole therapeutic process ineffective in the absence of an efficient delivery mechanism?
The drug delivery process.
What is the primary objective of a drug delivery system?
To extend, confine and target the drug in the diseased tissue with a protected interaction.
What is the main difference between conventional drug delivery systems and controlled drug delivery systems?
Controlled drug delivery systems provide a more targeted and sustained release of the drug, whereas conventional systems do not.
What role do intelligent biomaterials play in drug delivery?
They enable targeted and smart drug delivery using stimuli-responsive materials.
What is the significance of pharmacokinetics in drug delivery?
It studies the movement of the drug throughout the body and its effects on the body.
What is the advantage of nano-drug delivery over traditional delivery systems?
It allows for more targeted and controlled release of the drug at the cellular level.
What are the key challenges and future directions in controlled drug delivery?
The challenges include overcoming limitations of current systems and developing more targeted and efficient delivery methods.
This quiz covers the Biopharmaceutics Classification System (BCS) criteria for drugs based on permeability and solubility, as well as different routes of drug administration. Test your knowledge on drug classification and administration methods.
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