Basic Concepts in Human Virology Quiz
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Questions and Answers

What is the tiniest simplest form of life on earth according to the text?

  • Bacteria
  • Protozoa
  • Fungi
  • Virus (correct)
  • Why did 15th century Italians call the disease Influenza?

  • Because they believed it was caused by the influence of stars and plants (correct)
  • Because it was caused by bacteria
  • Because it originated from Asia
  • Because it affected the lungs
  • What is the term for an organism that must have a cell to replicate?

  • Archaea
  • Eukaryote
  • Virus (correct)
  • Prokaryote
  • Where does a virus become a 'virus particle' with no activity or metabolism?

    <p>Outside of the host cell</p> Signup and view all the answers

    What process allows a virus to replicate inside an infected cell?

    <p>Protein synthesis</p> Signup and view all the answers

    Why are viruses considered not cellular organisms?

    <p>Because they cannot perform metabolism on their own outside of a cell</p> Signup and view all the answers

    What is the key factor that determines the survival of viruses according to the text?

    <p>Spreading capacity</p> Signup and view all the answers

    'Virus-Host Equilibrium' refers to what concept?

    <p>'Virus-Host' relationship maintaining survival balance</p> Signup and view all the answers

    What is one of the major reasons why Ebola virus outbreaks are limited to Africa?

    <p>Africa has a specific ecological environment that favors the virus.</p> Signup and view all the answers

    In what year did Influenza virus of 1919 demonstrate better equilibrium?

    <p>1976</p> Signup and view all the answers

    Why is Ramesses V's preserved mummy mentioned in the text?

    <p>As an illustration of an ancient smallpox infection.</p> Signup and view all the answers

    Which characteristic is shared by all cellular life forms according to the text?

    <p>Ability to reproduce by division.</p> Signup and view all the answers

    Why did Dmitri Iwanowski's work in 1892 open the field called VIROLOGY?

    <p>He demonstrated that a small infectious agent smaller than bacteria can transmit disease.</p> Signup and view all the answers

    Why are viruses unable to survive on their own in most cases?

    <p>Viruses require a host cell for replication and survival.</p> Signup and view all the answers

    What major characteristic distinguishes virus particles from cellular organisms?

    <p>'DNA must be expressed all the time.'</p> Signup and view all the answers

    How did seasonal flu outbreaks differ between 1918 and 1957 according to the text?

    <p>'1918 had a higher death rate.'</p> Signup and view all the answers

    What is a characteristic of lysogenic viral replication?

    <p>Viral genome is incorporated into the host's chromosomes</p> Signup and view all the answers

    Which type of RNA viruses have complementary base sequences in their genome compared to viral mRNAs?

    <p>Negative-sense RNA viruses</p> Signup and view all the answers

    What is the main difference between segmented and non-segmented viruses?

    <p>Segmented viruses have their genome divided into many chromosomes</p> Signup and view all the answers

    Which phase of viral replication involves the production of viral proteins?

    <p>The assembly of new virus particles</p> Signup and view all the answers

    What enzyme is required to separate enzymes in a viral infection?

    <p>Protease</p> Signup and view all the answers

    In which type of RNA virus does the genome contain sequences similar to mRNA?

    <p>+ssRNA</p> Signup and view all the answers

    What is the initial step in the translation of -ssRNA viruses?

    <p>+ssRNA copying</p> Signup and view all the answers

    Which cells house viral memory cells that sustain lifelong infections?

    <p>White blood cells</p> Signup and view all the answers

    'Lytic' and 'Lysogenic' are terms related to which aspect of viral life cycles?

    <p>'Lytic' refers to a viral replication cycle, while 'Lysogenic' refers to a dormant state within the host.</p> Signup and view all the answers

    'Lyso' in lysogenic is derived from which word, hinting at its nature?

    <p>'Lysis'</p> Signup and view all the answers

    What did a virologist in the 20th century famously describe a virus as?

    <p>A piece of bad news wrapped in a protein</p> Signup and view all the answers

    When viruses can sense the presence of the immune system, what action do they typically take?

    <p>Reduce replication to avoid immune system detection</p> Signup and view all the answers

    In what year did the transfer of smallpox from Europe to the Americas occur?

    <p>1519 A.D</p> Signup and view all the answers

    Which virus infected about 350 million people worldwide in a chronic way?

    <p>Hepatitis B virus</p> Signup and view all the answers

    Which virus caused 50-100 million deaths worldwide during the 1918 pandemic?

    <p>Spanish Flu virus</p> Signup and view all the answers

    Which of the following are common causes of acute infections in humans according to the text?

    <p>Viruses</p> Signup and view all the answers

    What is a key characteristic of viruses in terms of their presence in the human genome?

    <p>Viruses account for the first 8% of our genome</p> Signup and view all the answers

    What is a characteristic shared by rabies, Ebola, and smallpox viruses according to the text?

    <p>High mortality rates</p> Signup and view all the answers

    What is a significant role that viruses like varicella zoster play in human infections according to the text?

    <p>Triggering early infections for immunity development</p> Signup and view all the answers

    What is the impact of the varicella zoster virus on human infections according to the text?

    <p>We need them to infect us early as possible</p> Signup and view all the answers

    What significant event occurred in 1519 A.D regarding smallpox?

    <p>Transferred from Europe to the Americas</p> Signup and view all the answers

    How did Hernando Cortes contribute to the spread of smallpox?

    <p>Invaded Mexico and conquered millions of Aztecs</p> Signup and view all the answers

    What factors contributed to the defenselessness of the Aztecs in the face of smallpox?

    <p>Less than 600 men helped, horses, weapons</p> Signup and view all the answers

    What were the major factors that caused significant mortality in the U.S according to the text?

    <p>Obesity, tobacco, and alcohol</p> Signup and view all the answers

    What is the most common cause of acute infections in humans according to the text?

    <p>Viruses</p> Signup and view all the answers

    How many total virus infections in the world exceed several billion cases each year in adults?

    <p>Several billions</p> Signup and view all the answers

    What viruses have high mortality rates according to the text?

    <p>Rabies, Ebola, smallpox</p> Signup and view all the answers

    Which viruses can lead to long-term disability?

    <p>Polio, rubella</p> Signup and view all the answers

    What is the key characteristic that distinguishes virus particles from cellular organisms according to the text?

    <p>They cannot survive on their own</p> Signup and view all the answers

    Explain the historical impact of viruses on human history.

    <p>Viruses have caused devastating diseases throughout history, impacting populations like war and natural disasters.</p> Signup and view all the answers

    What is the significance of the term 'Influenza' and why did 15th century Italians use it?

    <p>The term 'Influenza' was coined by 15th century Italians, who believed it was caused by the influence of stars and planets.</p> Signup and view all the answers

    Describe the concept of obligate intracellular parasites in relation to viruses.

    <p>Obligate intracellular parasites are viruses that require a host cell to replicate, as they cannot perform metabolism on their own.</p> Signup and view all the answers

    Explain the importance of virus-host equilibrium in the survival of viruses.

    <p>Virus-host equilibrium is crucial for the survival of viruses, as their natural evolution operates on spreading capacity rather than disease-causing ability.</p> Signup and view all the answers

    What is the role of mutants in the survival of viruses?

    <p>Viruses produce a large number of mutants to survive, with selection removing non-fittest strains.</p> Signup and view all the answers

    Discuss the impact of the death of an infected host on the survival of the infecting virus.

    <p>The death of an infected host compromises the survival of the infecting virus, as viruses cannot replicate without a host.</p> Signup and view all the answers

    Explain the process of viral replication inside an infected cell.

    <p>Inside an infected cell, a virus can replicate to make proteins, enter the nucleus, and produce genome proteins before leaving the cell.</p> Signup and view all the answers

    What is the main reason why viruses are considered not cellular organisms?

    <p>Viruses are not considered cellular organisms because they lack the ability to perform metabolism on their own outside of a host cell.</p> Signup and view all the answers

    Describe the natural evolution process of viruses in terms of spreading capacity.

    <p>The natural evolution of viruses operates on their spreading capacity rather than their ability to cause disease.</p> Signup and view all the answers

    How do viruses like varicella zoster impact human infections according to the text?

    <p>Viruses like varicella zoster play a significant role in causing acute infections in humans.</p> Signup and view all the answers

    What is the significance of the hieroglyph from Memphis in 3700BC?

    <p>First written record of a virus infection</p> Signup and view all the answers

    How did the Influenza virus of 1919 demonstrate better equilibrium?

    <p>Killing people but not at the same level as 1918</p> Signup and view all the answers

    What disease did Ramesses V die from in 1143 B.C.?

    <p>Smallpox</p> Signup and view all the answers

    What did Dmitri Iwanowski's work in 1892 lead to in the field of virology?

    <p>Birth of the field called VIROLOGY</p> Signup and view all the answers

    What is the impact of Ebola virus outbreaks on infected people?

    <p>Death up to 90% of infected people shortly after infection</p> Signup and view all the answers

    What is the impact of polio infection on most people?

    <p>Totally asymptomatic, can spread the virus</p> Signup and view all the answers

    How did seasonal flu outbreaks differ between 1918 and 1957?

    <p>1918 had a higher death toll</p> Signup and view all the answers

    What is the main characteristic of virus particles that distinguishes them from cellular organisms?

    <p>Not cellular organism</p> Signup and view all the answers

    What is the purpose of a virus solely replicating and infecting other host cells?

    <p>To make many copies and infect other host cells</p> Signup and view all the answers

    What did Dmitri Iwanowski's discovery reveal about infectious agents in 1892?

    <p>Smaller than a bacteria</p> Signup and view all the answers

    What is the major distinguishing factor between lytic and lysogenic viral replication cycles?

    <p>In lysogenic cycle, viruses are incorporated into the host's chromosome, while in lytic cycle, viruses are released from the host cell after replication.</p> Signup and view all the answers

    Explain the impact of HIV infection being lysogenic on human health.

    <p>HIV can stay in memory cells for life, leading to lifelong infection and continuous production of new virus particles.</p> Signup and view all the answers

    What is the main reason behind viruses like HIV infecting humans for life?

    <p>The infection of memory cells by HIV allows the virus to persist in the body indefinitely.</p> Signup and view all the answers

    How do segmented viruses, like rotavirus, differ from non-segmented viruses in terms of genome structure?

    <p>Segmented viruses have their genome made of many chromosomes, while non-segmented viruses have a single chromosome.</p> Signup and view all the answers

    Explain the significance of RNA-dependent RNA polymerase in viral replication.

    <p>RNA-dependent RNA polymerase is crucial for copying the viral RNA genome into a form that can be translated and used to produce viral proteins.</p> Signup and view all the answers

    What is the primary function of RNA-dependent RNA polymerase in a newly infected cell?

    <p>It helps in copying the viral RNA genome into a form suitable for translation into viral proteins.</p> Signup and view all the answers

    Describe the role of memory cells in sustaining lifelong infections by viruses like HIV.

    <p>Memory cells provide a reservoir for viruses to persist in the body, leading to lifelong infections.</p> Signup and view all the answers

    How does the presence of memory cells contribute to the chronicity of certain viral infections?

    <p>Memory cells act as a long-term reservoir for viruses, allowing them to continuously produce new virus particles.</p> Signup and view all the answers

    What is the significance of viral memory cells in the context of lifelong infections?

    <p>Viral memory cells provide a long-term source for continuous production of new virus particles, leading to lifelong infections.</p> Signup and view all the answers

    Explain the importance of separating viral enzymes in the infected cell during viral replication.

    <p>Separating viral enzymes allows for the activation of specific functions, such as producing structural or processed proteins.</p> Signup and view all the answers

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