Introduction to Human Viruses

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30 Questions

What is the primary characteristic of viruses?

They are acellular and nonliving

What is the structure of a virion composed of?

Virus genome, protein capsid, and may have an envelope

Which Baltimore class of viral genomes includes HIV and HTLV?

  • ss RNA with RT (Class VI)

What is the viral capsid primarily composed of?

Structural units called capsomeres

Which type of viral symmetry has 20 triangular faces, 12 vertices, and 30 edges?

Icosahedral (cubic)

"Recovery from infection or persistence" is a step in which process?

"Steps in viral pathogenesis"

What is the primary characteristic of the host range of viruses?

It can vary from narrow to wide host range.

Which type of nucleic acid is characteristic of Class III Baltimore viruses?

ds RNA

Which type of response is the adaptive response to viral infection?

Acquired

What is the outcome of a viral infection characterized by the presence of viral genome with no active replication, but with potential for reactivation?

Latent/Subclinical

What are the natural barriers of the body in host defense to viral infection?

Innate response

What is the process by which viral infection leads to disease known as?

Viral pathogenesis

What type of vaccine involves presenting a part of the pathogen to stimulate an immune response?

Subunit vaccine

What type of transmission is most common for viruses?

Horizontal transmission

What type of infection results in the host being a carrier of the virus?

Chronic infection

Which type of antiviral agent targets virus-specific components to avoid damage to the host?

Amantadine

What type of antiviral agent prevents attachment of viruses to host cells?

Maraviroc

Which book provides information on medical microbiology related to this presentation?

Mims Medical Microbiology, 5th edition, Chapters 3 and parts of 15, 16, 17

Which type of infection results in virus-induced immunopathological disease?

Persistent infection

Which outcome may lead to neoplasia due to prolonged presence and activity of the virus?

Transforming (Oncogenesis)

Which step in viral pathogenesis involves the release of virus from first infected cells?

Assembly

Which factor determines whether viral infection becomes localized or systemic?

Release of virus from first infected cells

What is the primary replication site for Rhinoviruses in systemic infections?

Upper respiratory tract

How are most viruses spread throughout the host's body?

The bloodstream

Which factor does NOT contribute to the selectivity of productive infection by viruses?

pH lability

What is the main route of entry for Hepatitis A virus?

Feco-oral transmission

Which virus primarily replicates in the oropharynx or urogenital tract?

Herpesvirus (HSV types 1 and 2)

What is the primary mode of transmission for Dengue fever?

Vector (arthropod-borne) transmission

Which type of transmission is characteristic of prenatal transmission of viruses?

Vertical transmission from mother to fetus

What determines whether viral infection remains local or becomes systemic?

Release of virus from first infected cells

Learn about the definition of viruses, viral structure, viral pathogenesis, outcomes of viral infections, and the control of viral infection in this introductory quiz.

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