Energy Metabolism
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Questions and Answers

What is the primary function of leptin in regulating adiposity?

  • To act as a negative feedback regulator of adiposity (correct)
  • To decrease the metabolic rate and conserve energy
  • To stimulate appetite and increase energy intake
  • To increase glucose uptake in adipose tissue
  • What is the term for the number of calories burned by the human body in one day?

  • Basal Metabolic Rate
  • Thermic Effect of Food
  • Total Energy Expenditure (correct)
  • Activity Energy Expenditure
  • What percentage of Total Energy Expenditure is accounted for by Resting Energy Expenditure?

  • 40-50%
  • 60-70%
  • 10-20%
  • 20-30% (correct)
  • Which of the following is a consequence of leptin resistance?

    <p>Overeating and consequent obesity</p> Signup and view all the answers

    What is the term for the energy released when the subject is at complete mental and physical rest?

    <p>Basal Metabolic Rate</p> Signup and view all the answers

    What is the primary factor that contributes to the development of overeating and obesity?

    <p>Reduced sensitivity of D2 receptors</p> Signup and view all the answers

    What is the percentage of Total Energy Expenditure accounted for by Activity Energy Expenditure?

    <p>60-70%</p> Signup and view all the answers

    What is the term for the process by which the body regulates energy intake and expenditure to maintain energy homeostasis?

    <p>Homeostatic Regulation</p> Signup and view all the answers

    Which of the following activities would have the lowest energy expenditure?

    <p>Sleeping</p> Signup and view all the answers

    What is the term used to express the energy cost of physical activities as a multiple of Basal Metabolic Rate (BMR)?

    <p>Metabolic Equivalent of Task (MET)</p> Signup and view all the answers

    What is the approximate range of PAR for sedentary activities?

    <p>1.1 to 1.2</p> Signup and view all the answers

    Which of the following is NOT a factor that contributes to Total Energy Expenditure (TEE)?

    <p>Body mass index (BMI)</p> Signup and view all the answers

    What does the term 'PAL' represent?

    <p>The sum of PARs of different activities</p> Signup and view all the answers

    According to the passage, what is the approximate TEE for a person engaged in sedentary or light activity, expressed in MJ?

    <p>8.26 MJ</p> Signup and view all the answers

    Which of the following is an example of a catabolic reaction?

    <p>Glycolysis</p> Signup and view all the answers

    Which of the following metabolic substrates is NOT a primary energy source for the body?

    <p>Vitamins</p> Signup and view all the answers

    What is the main difference between Basal Metabolic Rate (BMR) and Resting Metabolic Rate (RMR)?

    <p>BMR is the minimum calorie requirement at rest, whereas RMR accounts for additional energy used for processes.</p> Signup and view all the answers

    Which organ accounts for the highest percentage of Resting Energy Expenditure (REE)?

    <p>Liver</p> Signup and view all the answers

    Which of the following organs contributes the least to Resting Energy Expenditure on a weight basis?

    <p>Adipose tissue</p> Signup and view all the answers

    In the context of energy metabolism, what does TEF stand for?

    <p>Thermic Effect of Food</p> Signup and view all the answers

    How does the energy expenditure of muscle tissue at rest compare to that of the heart?

    <p>Muscle tissue's energy expenditure is significantly lower than that of the heart.</p> Signup and view all the answers

    What was the first equation used for estimating energy expenditure?

    <p>Harris-Benedict equation</p> Signup and view all the answers

    What percentage of Resting Energy Expenditure is contributed by the brain?

    <p>20%</p> Signup and view all the answers

    Which of the following statements about energy metabolism is inaccurate?

    <p>BMR is the same for all body types regardless of weight.</p> Signup and view all the answers

    Study Notes

    Energy Metabolism

    • BMR (Basal Metabolic Rate) is the minimum number of calories required for basic functions at rest.

    Resting Energy Expenditure vs BMR

    • Resting Energy Expenditure (REE) is also called Resting Metabolic Rate (RMR).
    • REE is the number of calories required for basic functions at rest, plus energy for organs with high energy needs.
    • Organs with high energy needs (5% of body weight) use 58% of REE:
      • Liver: 21% of total REE
      • Brain: 20% of total REE
      • Heart: 9% of total REE
      • Kidneys: 8% of total REE
    • Muscle Energy Expenditure (EE) is only 3% of heart's EE/g at rest, but comprises 22% of RMR at rest.
    • Adipose tissue has a lower EE/g and is always at rest:
      • 4% of RMR in lean individuals
      • Up to 10% of RMR in obese individuals

    Estimating BMR and REE

    • Several equations can be used to estimate energy expenditure, including the Harris-Benedict equation and the Institute of Medicine Equation for Estimated Energy Requirement (EER).

    Thermic Effect of Food (TEF)

    • TEF is the energy cost of digestion, absorption, processing, and storage of nutrients.

    Physical Activity in Energy Expenditure

    • The rate of energy expenditure ranges from low-energy activities (e.g., sleep) to high-energy activities (e.g., sprinting).
    • Physical activity includes movement of at least light intensity, extending to moderate and vigorous intensity.

    Energy Requirements Increase With Activity

    • The energy cost of physical activities is expressed as a multiple of BMR, known as the physical activity ratio (PAR) or metabolic equivalent of the task (MET).
    • Sedentary activities use about 1.1 to 1.2 × BMR, while vigorous activities use 6 to 8 × BMR.
    • Overall physical activity level (PAL) is the sum of the PAR of different activities.

    Energy Balance and Regulation

    • Leptin, a hormone secreted by adipocytes, acts as a negative feedback regulator of adiposity via leptin receptors in the hypothalamus.
    • Leptin resistance may contribute to overeating and obesity.
    • Reward signals, such as palatability and energy density, can contribute to overeating and obesity.
    • Homeostatic regulation of food intake involves the balance of energy expenditure and intake.

    Energy Balance – Energy Expenditure

    • Total Energy Expenditure (TEE) is the number of calories burned by the human body in one day.
    • TEE is composed of three primary factors:
      • Resting Energy Expenditure or basal metabolic rate (60-70%)
      • Thermic effect of food (10-30%)
      • Activity (20-30%)

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    Description

    Understand the difference between Basal Metabolic Rate (BMR) and Resting Metabolic Rate (RMR) and learn how they relate to energy metabolism in the human body. Important for understanding health and weight management.

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