Bailey & Love Chapter 1: Metabolic Response to Injury
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Questions and Answers

What is the term used to describe the physiological and biochemical changes that occur during injury and recovery?

  • Neural circuits response
  • Metabolic response to injury (correct)
  • Inflammatory cytokines response
  • Surgical stress response
  • Which of the following is NOT mentioned as a mediator involved in the metabolic response to injury?

  • Antibiotics (correct)
  • Cytokines
  • Hormones
  • Neural circuits
  • What is the potential consequence of the abnormal processes resulting from the metabolic response to injury?

  • Prolonged multiple organ dysfunction syndrome (MODS) (correct)
  • Decreased surgical stress response
  • Reduced risk of sepsis
  • Improved wound healing
  • Which of the following is affected by the surgical stress response?

    <p>Wound healing and immunity</p> Signup and view all the answers

    What leads to alterations in body metabolism, wound healing, and immunity during injury?

    <p>Inflammation-related cytokines</p> Signup and view all the answers

    What is the main cause of complications such as sepsis in the context of tissue injury?

    <p>Inflammation-related cytokines</p> Signup and view all the answers

    What is the main physiological role of the catabolic phase in the metabolic response to injury?

    <p>To conserve circulating volume and energy stores</p> Signup and view all the answers

    Which chapter covers shock, fluid balance, sepsis, and nutrition in greater depth?

    <p>Chapter 25</p> Signup and view all the answers

    What concept refers to maintaining a constant internal environment for optimal cellular function?

    <p>Homeostasis</p> Signup and view all the answers

    Which factor characterizes the catabolic phase of the metabolic response to injury?

    <p>Muscle breakdown and weight loss</p> Signup and view all the answers

    What is the role of surgical critical care during the metabolic effects of injury?

    <p>To work alongside the metabolic effects while restoring homeostasis</p> Signup and view all the answers

    What condition involves loss of muscle mass, sepsis, and MODS as systemic effects?

    <p>Catabolic phase</p> Signup and view all the answers

    During which phase does anabolic (rebuilding) phase develop after serious injury?

    <p>Catabolic phase subsiding</p> Signup and view all the answers

    What are the avoidable factors that compound the metabolic response to injury called?

    <p>Avoidable factors</p> Signup and view all the answers

    "Successful management of the metabolic response improves outcomes" - What is the basis of modern perioperative care?

    <p>&quot;Conserve both circulating volume and energy stores&quot;</p> Signup and view all the answers

    What is the primary purpose of resuscitation and/or organ support in surgical critical care?

    <p>Restore homeostasis alongside the metabolic effects of injury</p> Signup and view all the answers

    Study Notes

    Metabolic Response to Injury

    • The physiological and biochemical changes that occur during injury and recovery are described as the metabolic response to injury.

    Mediators of Metabolic Response

    • The mediators involved in the metabolic response to injury do not include bradykinin.

    Consequences of Metabolic Response

    • The abnormal processes resulting from the metabolic response to injury can lead to potential consequences such as sepsis, MODS, and multiple organ dysfunction syndrome.

    Surgical Stress Response

    • The surgical stress response affects glucose metabolism, proteolysis, and lipolysis.

    Alterations in Body Metabolism

    • The metabolic response to injury leads to alterations in body metabolism, wound healing, and immunity.

    Complications of Metabolic Response

    • The main cause of complications such as sepsis in the context of tissue injury is the metabolic response to injury.

    Catabolic Phase

    • The main physiological role of the catabolic phase in the metabolic response to injury is to mobilize energy stores and support the body's response to injury.
    • The catabolic phase is characterized by increased glucose production, proteolysis, and lipolysis.

    Importance of Homeostasis

    • The concept of maintaining a constant internal environment for optimal cellular function is known as homeostasis.

    Role of Surgical Critical Care

    • The role of surgical critical care during the metabolic effects of injury is to support the body's response to injury and manage complications.

    Systemic Effects of Metabolic Response

    • The condition that involves loss of muscle mass, sepsis, and MODS as systemic effects is known as cachexia.

    Anabolic Phase

    • The anabolic (rebuilding) phase develops after serious injury during the recovery phase.

    Avoidable Factors

    • The avoidable factors that compound the metabolic response to injury are known as iatrogenic factors.

    Basis of Modern Perioperative Care

    • The basis of modern perioperative care is that successful management of the metabolic response improves outcomes.

    Primary Purpose of Resuscitation and Organ Support

    • The primary purpose of resuscitation and/or organ support in surgical critical care is to restore tissue perfusion and prevent organ dysfunction.

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    Description

    Test your knowledge on the metabolic response to injury and surgery with this quiz based on Bailey & Love's principles. Learn about the physiological and biochemical changes that occur during injury and recovery, as well as the mediators and pathways of the metabolic response to injury.

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