16 Questions
What is the term used to describe the physiological and biochemical changes that occur during injury and recovery?
Metabolic response to injury
Which of the following is NOT mentioned as a mediator involved in the metabolic response to injury?
Antibiotics
What is the potential consequence of the abnormal processes resulting from the metabolic response to injury?
Prolonged multiple organ dysfunction syndrome (MODS)
Which of the following is affected by the surgical stress response?
Wound healing and immunity
What leads to alterations in body metabolism, wound healing, and immunity during injury?
Inflammation-related cytokines
What is the main cause of complications such as sepsis in the context of tissue injury?
Inflammation-related cytokines
What is the main physiological role of the catabolic phase in the metabolic response to injury?
To conserve circulating volume and energy stores
Which chapter covers shock, fluid balance, sepsis, and nutrition in greater depth?
Chapter 25
What concept refers to maintaining a constant internal environment for optimal cellular function?
Homeostasis
Which factor characterizes the catabolic phase of the metabolic response to injury?
Muscle breakdown and weight loss
What is the role of surgical critical care during the metabolic effects of injury?
To work alongside the metabolic effects while restoring homeostasis
What condition involves loss of muscle mass, sepsis, and MODS as systemic effects?
Catabolic phase
During which phase does anabolic (rebuilding) phase develop after serious injury?
Catabolic phase subsiding
What are the avoidable factors that compound the metabolic response to injury called?
Avoidable factors
"Successful management of the metabolic response improves outcomes" - What is the basis of modern perioperative care?
"Conserve both circulating volume and energy stores"
What is the primary purpose of resuscitation and/or organ support in surgical critical care?
Restore homeostasis alongside the metabolic effects of injury
Study Notes
Metabolic Response to Injury
- The physiological and biochemical changes that occur during injury and recovery are described as the metabolic response to injury.
Mediators of Metabolic Response
- The mediators involved in the metabolic response to injury do not include bradykinin.
Consequences of Metabolic Response
- The abnormal processes resulting from the metabolic response to injury can lead to potential consequences such as sepsis, MODS, and multiple organ dysfunction syndrome.
Surgical Stress Response
- The surgical stress response affects glucose metabolism, proteolysis, and lipolysis.
Alterations in Body Metabolism
- The metabolic response to injury leads to alterations in body metabolism, wound healing, and immunity.
Complications of Metabolic Response
- The main cause of complications such as sepsis in the context of tissue injury is the metabolic response to injury.
Catabolic Phase
- The main physiological role of the catabolic phase in the metabolic response to injury is to mobilize energy stores and support the body's response to injury.
- The catabolic phase is characterized by increased glucose production, proteolysis, and lipolysis.
Importance of Homeostasis
- The concept of maintaining a constant internal environment for optimal cellular function is known as homeostasis.
Role of Surgical Critical Care
- The role of surgical critical care during the metabolic effects of injury is to support the body's response to injury and manage complications.
Systemic Effects of Metabolic Response
- The condition that involves loss of muscle mass, sepsis, and MODS as systemic effects is known as cachexia.
Anabolic Phase
- The anabolic (rebuilding) phase develops after serious injury during the recovery phase.
Avoidable Factors
- The avoidable factors that compound the metabolic response to injury are known as iatrogenic factors.
Basis of Modern Perioperative Care
- The basis of modern perioperative care is that successful management of the metabolic response improves outcomes.
Primary Purpose of Resuscitation and Organ Support
- The primary purpose of resuscitation and/or organ support in surgical critical care is to restore tissue perfusion and prevent organ dysfunction.
Test your knowledge on the metabolic response to injury and surgery with this quiz based on Bailey & Love's principles. Learn about the physiological and biochemical changes that occur during injury and recovery, as well as the mediators and pathways of the metabolic response to injury.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
