Bacterial Cell Wall Structure
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Questions and Answers

Which type of antibacterial targets bacteria without significant negative effects on mammalian cells?

  • Antibiotics inhibiting tetrapeptide crosslinking
  • Broad-spectrum antibiotics
  • Antibiotics affecting peptidoglycan biosynthesis (correct)
  • Antibiotics targeting porins
  • What is the primary component of the bacterial cell wall structure?

  • Fosfomycin
  • Peptidoglycan (correct)
  • Chloramphenicol
  • Penicillin G
  • Which type of antibiotic affects both gram-positive and some gram-negative bacteria?

  • CBIs inhibiting tetrapeptide crosslinking
  • Broad-spectrum antibiotics (correct)
  • Narrow-spectrum antibiotics
  • Antibiotics targeting porins
  • What is the function of peptidoglycan in bacterial cells?

    <p>Regulate osmotic pressure</p> Signup and view all the answers

    Which step in peptidoglycan biosynthesis do fosfomycin-type antibiotics primarily inhibit?

    <p>Disaccharide production inside the cell</p> Signup and view all the answers

    Which class of antibiotics has been particularly effective due to their action on cell wall biosynthesis?

    <p>Cell wall biosynthesis inhibitors (CBIs)</p> Signup and view all the answers

    What is the primary component of the cell wall in both Gram-positive and Gram-negative bacteria?

    <p>Peptidoglycan</p> Signup and view all the answers

    How does the cell wall composition of eukaryotic microbes differ from that of bacteria?

    <p>Eukaryotic cell walls contain a single component, while bacterial cell walls are more complex</p> Signup and view all the answers

    What is the function of the porin channels in the outer membrane of Gram-negative bacteria?

    <p>To control the entry of nutrients and waste products</p> Signup and view all the answers

    What is the role of the tetrapeptide component in the peptidoglycan structure?

    <p>It cross-links the peptidoglycan strands</p> Signup and view all the answers

    How do the cell wall thicknesses of Gram-positive and Gram-negative bacteria compare?

    <p>Gram-positive bacteria have a thicker cell wall than Gram-negative bacteria</p> Signup and view all the answers

    What is the main structural difference between the cell walls of Gram-positive and Gram-negative bacteria?

    <p>Gram-positive bacteria have a single-layered cell wall, while Gram-negative bacteria have a two-layered cell wall</p> Signup and view all the answers

    What is the primary function of the mycobacterial cell wall?

    <p>To provide structural support and protection</p> Signup and view all the answers

    Which of the following statements about the composition of the mycobacterial cell wall is correct?

    <p>It contains a high proportion of complex lipids, contributing to its hydrophobicity.</p> Signup and view all the answers

    What is the role of arabinogalactan in the mycobacterial cell wall?

    <p>It is a structural component that links peptidoglycan and mycolic acids.</p> Signup and view all the answers

    Which component of the mycobacterial cell wall contributes to its thickness and physical barrier properties?

    <p>Peptidoglycan</p> Signup and view all the answers

    What is the primary function of mycolic acids in the mycobacterial cell wall?

    <p>To provide structural rigidity and shape to the cell wall</p> Signup and view all the answers

    Which of the following statements about the peptidoglycan layer in the mycobacterial cell wall is true?

    <p>Its organization is dynamic and can change in response to environmental conditions.</p> Signup and view all the answers

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