Antimicrobials for skin disease

<p>Do appropriate diagnostics</p> Signup and view all the answers

<p>Topical products</p> Signup and view all the answers

<p>Use narrowest spectrum and lowest tier drug</p> Signup and view all the answers

<p>If systemic infection is noted</p> Signup and view all the answers

<p>Correct any underlying cause</p> Signup and view all the answers

<p>Combination of topical and systemic antibiotics</p> Signup and view all the answers

<p>4-6 weeks</p> Signup and view all the answers

<p>Doxycycline</p> Signup and view all the answers

<p>7-10 days</p> Signup and view all the answers

<p>Topical antibacterial</p> Signup and view all the answers

<p>Poulticing and hot compresses</p> Signup and view all the answers

<p>Leave it untreated</p> Signup and view all the answers

<p>Topical antifungals</p> Signup and view all the answers

<p>Enilconazole</p> Signup and view all the answers

<p>Ketoconazole</p> Signup and view all the answers

<p>Pruritus</p> Signup and view all the answers

<p>Debride and lavage with 2-4% chlorhexidine</p> Signup and view all the answers

<p>Trimethoprim/sulphonamide</p> Signup and view all the answers

<p>Topical treatment with 2-4% chlorhexidine</p> Signup and view all the answers

<p>Culture and sensitivity testing</p> Signup and view all the answers

<p>Minimum 3 weeks</p> Signup and view all the answers

<p>Debride and lavage</p> Signup and view all the answers

<p>Trimethoprim/sulphonamide</p> Signup and view all the answers

<p>Systemic antibacterials based on cytology</p> Signup and view all the answers

<p>Topical treatment only, using drugs such as Framycetin, Gentamycin, Polymyxin B, Florfenicol, Fusidic acid/framycetin, or Polymyxin B/miconazole.</p> Signup and view all the answers

<p>For small areas of superficial infection, use topical anti-bacterials/antiseptics such as chlorhexidine-based products or tetracycline/thiamphenicol spray. For larger areas, use a non-critically-important systemic antibiotic such as penicillin, cephalosporins, or oxytetracycline.</p> Signup and view all the answers

<p>Avoid lancing and draining the abscess due to the caseous nature of rabbit pus. Antibiotics are unlikely to be curative and are normally used in conjunction with surgical management. Culture and susceptibility testing should ideally be performed on a section of the abscess wall, not the pus.</p> Signup and view all the answers

<p>Antifungal therapy may be required for maintenance therapy if the underlying cause persists. However, it is important not to use a polypharmacy product with an antibiotic. It is better to establish and correct/control the underlying cause where possible.</p> Signup and view all the answers

<p>It is important to be sure of what you are treating by doing appropriate diagnostics. Use topical products where possible. If systemic antibiotics are required, use the narrowest spectrum and lowest tier drug that is likely to be effective.</p> Signup and view all the answers

<p>Bacterial and C&amp;S testing should be done if rods are seen on cytology, if there are deep infections, if there is poor response to prior antibiotics, or if a resistant organism is suspected.</p> Signup and view all the answers

<p>It is important to treat an infection long enough to fully resolve it, but no longer than necessary. Additionally, it is important to correct any underlying cause, as prevention is better than cure.</p> Signup and view all the answers

<p>Ensure bacteria are involved – do cytology whenever possible. Antibacterial treatment not suitable for, e.g. Malassezia dermatitis, Treatment of non-specific skin problems (e.g. pruritus). Use topical antibacterials/antibiotics where possible - minimise use of systemic antibiotics. Use the narrowest spectrum and lowest tier antibiotic that is likely to be effective. Correct the underlying cause.</p> Signup and view all the answers

<p>Debride and lavage if systemically well and no pyrexic: Topical treatment with 2-4% chlorhexidine. If systemically unwell and pyrexic: Systemic antibacterials based on cytology: For cocci: Clindamycin, Cefalexin, Amoxicillin/clavulanate, Trimethoprim/sulphonamide. For rods: Flouroquinolones.</p> Signup and view all the answers

<p>Topical only treatment: 2-4% chlorhexidine, Fusidic acid +/- glucocorticoid, Silver sulphadiazine (if rods). If required: Clindamycin, Cefalexin, Amoxicilline/clavulanate, Trimethoprim/sulphonamide. Culture if rods are seen on cytology or there is a history of MRSP/MRSA or multiple prior antibacterial courses. Treat for minimum 3 weeks or 1 week beyond clinical cure. Repeat cytology to assess response. Use doses at top end of range for better skin penetration.</p> Signup and view all the answers