Autonomic Nervous System Quiz

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Questions and Answers

What is the primary role of sympathetic tone in arterioles?

  • To constrict systemic arterioles (correct)
  • To reduce blood pressure
  • To dilate systemic arterioles
  • To maintain digestive functions

The vagus nerve increases the intrinsic activity of the sino-atrial node.

False (B)

What two hormones does sympathetic tone stimulate the secretion of from the adrenal medulla?

Epinephrine and Norepinephrine

The activation of parasympathetic nerves to the penis leads to ________.

<p>erection</p> Signup and view all the answers

Match the following organs with their corresponding ANS division:

<p>Adrenal medulla = Sympathetic only Cutaneous blood vessels = Sympathetic only Constrictor pupillae = Parasympathetic only Oesophagus = Parasympathetic only</p> Signup and view all the answers

Which of the following is an example of dual antagonistic effects?

<p>Increased heart rate by sympathetic and decreased by parasympathetic (C)</p> Signup and view all the answers

Parasympathetic activation of the salivary glands results in the production of thick, viscous saliva.

<p>False (B)</p> Signup and view all the answers

Which division of the ANS is responsible for stimulating sweat glands?

<p>Sympathetic nervous system</p> Signup and view all the answers

What is the primary cause of myasthenia gravis?

<p>Autoimmune response against nicotinic receptors (D)</p> Signup and view all the answers

Pheochromocytoma is characterized by decreased secretion of epinephrine and norepinephrine.

<p>False (B)</p> Signup and view all the answers

What is a main symptom of Horner syndrome?

<p>Ptosis</p> Signup and view all the answers

Myasthenia gravis primarily affects the ________ muscles, leading to various symptoms.

<p>skeletal</p> Signup and view all the answers

Which of the following treatments is used for myasthenia gravis?

<p>Neostigmine (B)</p> Signup and view all the answers

Match the following conditions with their descriptions:

<p>Myasthenia gravis = Extreme muscular weakness due to autoimmune response Horner syndrome = Disruption of sympathetic innervation causing ptosis Raynaud's phenomenon = Reduced blood flow to fingers and toes during cold exposure Pheochromocytoma = Tumor causing excessive secretion of epinephrine and norepinephrine</p> Signup and view all the answers

Raynaud's phenomenon is commonly exacerbated by exposure to heat.

<p>False (B)</p> Signup and view all the answers

What can lead to death in severe cases of myasthenia gravis?

<p>Weakness of respiratory muscles</p> Signup and view all the answers

What is the primary function of the sympathetic nervous system during a stressful situation?

<p>Increases heart rate and muscle activity (A)</p> Signup and view all the answers

The parasympathetic nervous system is primarily responsible for the 'fight or flight' response.

<p>False (B)</p> Signup and view all the answers

What is meant by 'dual innervation' in the context of the autonomic nervous system?

<p>It refers to the control of many organs by both the sympathetic and parasympathetic nervous systems.</p> Signup and view all the answers

The sympathetic nervous system is also known for its __________ action during stress.

<p>mass discharge</p> Signup and view all the answers

Which of the following is an example of parasympathetic action?

<p>Secretion of saliva (B)</p> Signup and view all the answers

Match the nervous systems to their corresponding actions:

<p>Sympathetic Nervous System = Fight or flight response Parasympathetic Nervous System = Rest and digest functions Sympathetic Tone = Continual activity of the sympathetic system Parasympathetic Tone = Continual activity of the parasympathetic system</p> Signup and view all the answers

Parasympathetic reflexes usually act on multiple organs at once.

<p>False (B)</p> Signup and view all the answers

What is the result of increased activity in the sympathetic nervous system?

<p>It corresponds to a decrease in activity in the parasympathetic nervous system.</p> Signup and view all the answers

Which of the following are symptoms of organophosphate poisoning? (Select all that apply)

<p>Urination (B), Diarrhea (C), Miosis (D)</p> Signup and view all the answers

Myasthenia gravis is an autoimmune disease.

<p>True (A)</p> Signup and view all the answers

What treatment is commonly used for organophosphate poisoning?

<p>Atropine</p> Signup and view all the answers

Paralytic ileus is primarily caused by increased __________ activity.

<p>sympathetic</p> Signup and view all the answers

Match the symptoms with their corresponding conditions:

<p>Diarrhea = Organophosphate poisoning Constipation = Paralytic ileus Bradycardia = Organophosphate poisoning Abdominal distension = Paralytic ileus</p> Signup and view all the answers

Which option is NOT a treatment for paralytic ileus?

<p>Surgical removal of tumor (A), Drugs to decrease heart rate (C)</p> Signup and view all the answers

All body organs receive dual innervation of sympathetic and parasympathetic nerves.

<p>False (B)</p> Signup and view all the answers

What are the manifestations of increased arterial blood pressure due to vasoconstriction?

<p>Headache and increased heart rate</p> Signup and view all the answers

Flashcards

Sympathetic Mass Discharge

The sympathetic nervous system elicits a widespread response throughout the body, activating various organs in a coordinated manner, like a general alarm.

Parasympathetic Localized Action

The parasympathetic nervous system often targets specific organs, triggering localized actions, impacting a smaller area.

Sympathetic Tone

A state of continuous, low-level activity of the sympathetic nervous system, influencing various bodily functions at baseline.

Sympathetic Impact on Heart Rate

The heart rate is increased by the sympathetic nervous system, activating the heart to beat faster.

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Parasympathetic Impact on Heart Rate

The parasympathetic nervous system slows down the heart rate, acting like a brake on the heart.

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Parasympathetic 'Rest-and-Digest' Functions

The parasympathetic nervous system promotes 'rest-and-digest' functions, like digestion and relaxation, aiding bodily processes.

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Dual Innervation Advantage

Dual innervation by both sympathetic and parasympathetic nervous systems allows for precise control over an organ's function, ensuring a nuanced response.

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Reciprocal Control of Sympathetic and Parasympathetic Systems

The sympathetic and parasympathetic systems often work in balance, reciprocal control – increased activity in one is usually accompanied by decreased activity in the other.

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What is Myasthenia Gravis?

An autoimmune disease where antibodies attack acetylcholine receptors at the neuromuscular junction, leading to muscle weakness, fatigue, and potential respiratory problems.

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What is Horner Syndrome?

A condition caused by interruption of the sympathetic nervous system's supply to the face, resulting in an array of symptoms affecting one side of the face.

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What is Raynaud's Phenomenon?

A condition triggered by blood vessel spasms, leading to decreased blood flow to fingers and toes during cold exposure or stress.

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What is a Pheochromocytoma?

A tumor in the adrenal medulla that causes excessive release of epinephrine and norepinephrine, leading to widespread sympathetic nervous system activation.

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What is Neostigmine used for?

A medication used to treat Myasthenia Gravis by inhibiting the breakdown of acetylcholine, increasing its availability at the neuromuscular junction.

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What are Autonomic Disorders?

A group of disorders affecting the autonomic nervous system, which regulates involuntary bodily functions such as heart rate, digestion, and blood pressure.

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Define Myasthenia gravis' 'muscular weakness'

Extreme muscular weakness, often occurring after physical activity. This is a common symptom of Myasthenia Gravis.

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What is Anhidrosis?

Reduced sweating on one side of the face, commonly observed in Horner Syndrome.

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Sympathetic Tone in Arterioles

The sympathetic nervous system's baseline activity that keeps most systemic arterioles slightly constricted, contributing to maintaining arterial blood pressure.

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Sympathetic Tone and Adrenal Medulla

The adrenal medulla constantly secretes small amounts of adrenaline (epinephrine) and noradrenaline (norepinephrine) under the influence of sympathetic tone, helping to regulate blood pressure and blood sugar levels.

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Parasympathetic Tone in the Gut

The parasympathetic nervous system's baseline activity that keeps the gastrointestinal tract slightly contracted, preventing distention and promoting a small amount of digestive juice secretion.

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Vagal Tone on the Heart

The vagus nerve (10th cranial nerve) continuously exerts a slight influence on the sino-atrial node (SAN) reducing its intrinsic heart rate from 100 beats per minute to approximately 70 beats per minute.

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Dual Innervation of the ANS

Dual innervation occurs when an organ receives input from both the sympathetic and parasympathetic nervous systems, allowing for fine control of its function.

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Antagonistic Dual Innervation

Dual antagonistic effects occur when the sympathetic and parasympathetic systems have opposing effects on an organ. For example, sympathetic stimulation increases heart rate, while parasympathetic stimulation decreases it.

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Complementary Dual Innervation

Organs with dual innervation can experience complementary effects, where both systems work together to stimulate the same function but with different mechanisms. For example, both systems stimulate saliva production but with different qualities.

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Cooperative Dual Innervation

Dual cooperative effects involve the sympathetic and parasympathetic systems working in sequence to achieve a complex function. For example, parasympathetic stimulation causes an erection, while sympathetic stimulation causes ejaculation.

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Sympathetic Overactivity

A condition where the sympathetic nervous system is overstimulated, leading to various symptoms like increased heart rate, sweating, and anxiety.

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Paralytic Ileus

A condition characterized by paralysis of the intestines, preventing the passage of food and leading to symptoms like abdominal pain, distension, and constipation.

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Organophosphates

A group of chemicals that inhibit the enzyme acetylcholinesterase, leading to a buildup of acetylcholine and excessive stimulation of both nicotinic and muscarinic receptors.

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Myasthenia Gravis

An autoimmune disease causing weakness in skeletal muscles due to antibodies attacking acetylcholine receptors.

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Horner's Syndrome

A condition affecting one side of the face due to damage to the sympathetic nervous system, causing symptoms like drooping eyelid, constricted pupil, and decreased sweating.

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DUMBELS

A collection of symptoms associated with organophosphate poisoning, characterized by diarrhea, urination, miosis, bradycardia, bronchospasm, muscle excitation, lacrimation, salivation, and sweating.

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Muscarinic Cholinergic Receptor Antagonist

The use of a drug to block the effects of acetylcholine at the muscarinic receptors, often used to treat organophosphate poisoning.

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Surgical Removal of Tumor

The removal of a tumor, a common treatment for sympathetic overactivity caused by tumors.

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Study Notes

Autonomic Nervous System

  • The autonomic nervous system (ANS) controls involuntary functions, such as heart rate and digestion
  • It has two branches: sympathetic and parasympathetic
  • The sympathetic nervous system prepares the body for "fight-or-flight" responses
  • The parasympathetic nervous system promotes "rest-and-digest" responses

Mode of Action of Sympathetic and Parasympathetic Nervous System

  • Dual innervation: Many organs receive input from both the sympathetic and parasympathetic systems
  • Antagonistic effects: The two systems often have opposing effects. For example, sympathetic nerves increase heart rate while parasympathetic nerves decrease it
  • Cooperative effects: Sometimes, the two systems work together to achieve a coordinated response. For example, both systems contribute to salivation, though sympathetic saliva is thick and parasympathetic saliva is watery
  • Complementary effects: Both systems may stimulate an organ simultaneously, each in its own way. While in some instances one system has a strong effect, the other system's effect might be subtle, but it is still there
  • Sympathetic tone: The continuous activity of the sympathetic system helps maintain a baseline level of blood pressure and other functions.
  • Parasympathetic tone: The continuous activity of the parasympathetic system helps maintain normal functions in many organs, such as digestion
  • Localized actions: Sometimes, the sympathetic nervous system affects only the local area being stimulated (e.g., sweating during heat regulation)

Autonomic Disorders

  • Myasthenia gravis: An autoimmune disease where antibodies attack nicotinic receptors in the neuromuscular junction, resulting in muscle weakness
  • Horner syndrome: An interruption of sympathetic innervation to the face. It characteristically involves symptoms like pupil constriction, and reduced sweating on the affected side
  • Raynaud's phenomenon: Arterial spasms reduce blood flow to fingers and toes, causing symptoms including pallor, coldness, and numbness
  • Pheochromocytoma: A tumour of the adrenal medulla that causes excessive secretion of epinephrine and norepinephrine, typically causing high blood pressure, and sweating
  • Paralytic ileus: A decrease in intestinal motility preventing food's passage through the digestive tract, often linked to abdominal surgery, certain drugs, or electrolyte imbalances

Organophosphates

  • Organophosphates (pesticides and nerve gases) block acetylcholinesterase, leading to prolonged acetylcholine activity. This causes overstimulation of receptors leading to various symptoms
  • Treatment usually involves muscarinic cholinergic receptor antagonists like atropine

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