Autonomic Nervous System Drug Classes
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Questions and Answers

Which type of drug is used to treat asthma by mimicking the effects of adrenaline and noradrenaline?

  • Sympathomimetic (correct)
  • Parasympathomimetic
  • Parasympatholytic
  • Sympatholytic

A medication that blocks muscarinic receptors would be classified as which of the following?

  • Sympathomimetic
  • Beta Agonist
  • Cholinergic Agonist
  • Anti-Muscarinic (correct)

Which of these best describes the mechanism of action for a sympatholytic drug?

  • Blockage of all cholinergic receptors
  • Blockage of adrenergic receptors (correct)
  • Stimulation of the parasympathetic nervous system
  • Activation of muscarinic receptors

If a patient takes a medication that increases salivation, which type of receptor is most likely being affected?

<p>Muscarinic receptors (C)</p> Signup and view all the answers

Which drug class is associated with the treatment of overactive bladder?

<p>Anti-Muscarinic (C)</p> Signup and view all the answers

A medication that is described as a 'beta-blocker' belongs to which category of drugs?

<p>Sympatholytic (A)</p> Signup and view all the answers

If a drug is described as 'pertaining to the actions of acetylcholine,' which of the following classifications would it most closely fit?

<p>Cholinergic (B)</p> Signup and view all the answers

Which of the following best describes the function of a parasympathomimetic drug?

<p>Mimicking the effects of acetylcholine (B)</p> Signup and view all the answers

Which medication primarily activates beta-2 adrenergic receptors?

<p>Albuterol (B)</p> Signup and view all the answers

Atenolol is primarily known for which action?

<p>Beta-1 selective blocker (C)</p> Signup and view all the answers

What is the primary mechanism of action for beta-antagonists?

<p>Inhibit beta-adrenergic receptors (C)</p> Signup and view all the answers

Which of these medications is not used to treat heart conditions?

<p>Albuterol (B)</p> Signup and view all the answers

What does a 'Sympathomimetic' drug do?

<p>Activates the sympathetic nervous system (B)</p> Signup and view all the answers

What of the following is a primary use of a beta agonist?

<p>Bronchodilation in asthma (A)</p> Signup and view all the answers

What receptor type is primarily blocked by Propranolol?

<p>Both beta-1 and beta-2 adrenergic receptors (C)</p> Signup and view all the answers

Which drug class works by blocking muscarinic receptors?

<p>Anti-Muscarinics (C)</p> Signup and view all the answers

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Which classes of drugs are used to modulate the autonomic nervous system?

<p>Beta-blockers (A)</p> Signup and view all the answers

Which drug class primarily inhibits the activity of the sympathetic nervous system?

<p>Beta-blockers (A)</p> Signup and view all the answers

Which drug class primarily inhibits the parasympathetic nervous system?

<p>Anticholinergics (B)</p> Signup and view all the answers

Flashcards

Sympathomimetic (Adrenergic Agonists)

Drugs that stimulate the sympathetic nervous system (SNS) by mimicking the effects of adrenaline and noradrenaline. They activate adrenergic receptors (alpha and beta receptors).

Sympatholytic (Anti-Adrenergic or Adrenergic Antagonists)

Drugs that inhibit the SNS by blocking the effects of adrenaline and noradrenaline. They work by blocking adrenergic receptors (alpha and beta receptors).

Parasympathomimetic (Cholinergic Agonists)

Drugs that stimulate the parasympathetic nervous system (PNS) by mimicking the effects of acetylcholine. They activate muscarinic or nicotinic receptors.

Parasympatholytic (Anti-Cholinergic or Anti-Muscarinic)

Drugs that inhibit the PNS by blocking the effects of acetylcholine. They work by blocking muscarinic receptors.

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Beta Agonists (Beta-Adrenergic Agonists)

Drugs that specifically stimulate beta-adrenergic receptors, part of the sympathetic nervous system.

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Anti-Muscarinic (Muscarinic Antagonists)

Drugs that block the muscarinic acetylcholine receptors, inhibiting the PNS.

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Cholinergic (Related to Acetylcholine)

Pertaining to the actions of acetylcholine, a neurotransmitter in the PNS.

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Muscarinic (Related to Muscarinic Receptors)

Pertaining to the actions of muscarinic receptors, a type of cholinergic receptor in the PNS, activated by acetylcholine.

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Sympatholytic (Anti-Adrenergic)

Drugs that block adrenergic receptors, inhibiting the SNS.

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Parasympatholytic (Anti-Cholinergic)

Drugs that block muscarinic cholinergic receptors, inhibiting the PNS.

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Beta Agonists

Drugs that activate beta-1, beta-2, or beta-3 adrenergic receptors, stimulating the SNS.

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Beta Antagonists (Beta Blockers)

Drugs that block beta-1, beta-2, or beta-3 adrenergic receptors, inhibiting the SNS.

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What are Beta-2 agonists used for?

These drugs are used to treat asthma by dilating the bronchi.

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What are Beta-1 agonists used for?

These drugs are used to treat heart failure by increasing the heart's output.

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Study Notes

Autonomic Nervous System Drug Classes

  • Sympathomimetic (Adrenergic Agonists):

    • Definition: Mimic the sympathetic nervous system, using adrenaline and noradrenaline.
    • Mechanism: Activate alpha and beta receptors.
    • Examples: Epinephrine, Albuterol, Dobutamine.
    • Uses: Asthma, cardiac arrest, and hypotension.
  • Sympatholytic (Anti-Adrenergic or Adrenergic Antagonists):

    • Definition: Inhibit the sympathetic nervous system by blocking adrenaline and noradrenaline effects.
    • Mechanism: Block alpha and beta receptors.
    • Examples: Propranolol (beta-blocker) and clonidine (alpha-2 agonist).
    • Uses: Hypertension, anxiety, and heart arrhythmias.
  • Parasympathomimetic (Cholinergic Agonists):

    • Definition: Mimic the parasympathetic nervous system, using acetylcholine.
    • Mechanism: Activate muscarinic or nicotinic receptors.
    • Examples: Pilocarpine, Bethanechol.
    • Uses: Glaucoma and urinary retention.
  • Parasympatholytic (Anti-Cholinergic or Anti-Muscarinic):

    • Definition: Inhibit the parasympathetic nervous system by blocking acetylcholine.
    • Mechanism: Block muscarinic receptors.
    • Examples: Atropine, Ipratropium.
    • Uses: Bradycardia, reduce salivation, and manage COPD.
  • Cholinergic (Related to Acetylcholine):

    • Definition: Pertaining to the actions of acetylcholine.
    • Mechanism: Involves muscarinic or nicotinic receptors.
    • Examples: Acetylcholine, Nicotine.
    • Uses: Same as parasympathomimetics.
  • Anti-Muscarinic (Muscarinic Antagonists):

    • Definition: Block muscarinic acetylcholine receptors, inhibiting the parasympathetic nervous system (PNS).
    • Mechanism: Compete with acetylcholine for muscarinic receptors.
    • Examples: Scopolamine, oxybutynin.
    • Uses: Treat motion sickness, overactive bladder.
  • Muscarinic (Related to Muscarinic Receptors):

    • Definition: Relating to muscarinic receptors, a type of cholinergic receptor.
    • Mechanism: Activated by acetylcholine.
    • Examples: Muscarine (fungi), bethanechol.
    • Uses: Stimulate PNS actions (e.g., increasing salivation, bladder contraction).
  • Beta Agonists (Beta-Adrenergic Agonists):

    • Definition: Drugs stimulating beta-adrenergic receptors.
    • Mechanism: Activate beta-1, beta-2, or beta-3 receptors.
    • Examples: Albuterol (beta-2), dobutamine (beta-1).
    • Uses: Asthma, heart failure (increasing cardiac output).
  • Beta Antagonists (Beta Blockers):

    • Definition: Block beta-adrenergic receptors.
    • Mechanism: Inhibit beta-1, beta-2, or beta-3 receptors.
    • Examples: Propranolol (non-selective), atenolol (beta-1 selective).
    • Uses: Hypertension, angina, and heart arrhythmias.

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Description

Explore the different drug classes affecting the autonomic nervous system. This quiz covers sympathomimetic, sympatholytic, parasympathomimetic, and parasympatholytic drugs, their mechanisms, examples, and clinical uses. Perfect for students of pharmacology and medicine!

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