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Questions and Answers
What triggers the exocytosis of synaptic vesicles?
What triggers the exocytosis of synaptic vesicles?
What type of receptors do adrenergic receptors belong to?
What type of receptors do adrenergic receptors belong to?
What does the binding of norepinephrine (NE) to its receptor lead to?
What does the binding of norepinephrine (NE) to its receptor lead to?
How does an increase in neurotransmitter concentration affect the response?
How does an increase in neurotransmitter concentration affect the response?
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Which ion is specifically involved in the opening of voltage-gated channels during neurotransmitter release?
Which ion is specifically involved in the opening of voltage-gated channels during neurotransmitter release?
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What is a notable characteristic of the response mediated by adrenergic receptors?
What is a notable characteristic of the response mediated by adrenergic receptors?
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What type of control is primarily observed at the SA node in contrast to the ventricles and blood vessels?
What type of control is primarily observed at the SA node in contrast to the ventricles and blood vessels?
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Which neurotransmitter is primarily used in sympathetic pathways?
Which neurotransmitter is primarily used in sympathetic pathways?
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What percentage of all parasympathetic fibers does the vagus nerve contain?
What percentage of all parasympathetic fibers does the vagus nerve contain?
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What is the primary function of the vagus nerve in the autonomic nervous system?
What is the primary function of the vagus nerve in the autonomic nervous system?
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What role do sympathetic ganglia play in the autonomic nervous system?
What role do sympathetic ganglia play in the autonomic nervous system?
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What type of control do veins and arterioles primarily exhibit?
What type of control do veins and arterioles primarily exhibit?
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Which statement accurately describes the neurotransmitters used in parasympathetic pathways?
Which statement accurately describes the neurotransmitters used in parasympathetic pathways?
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Why is antagonistic control not seen in ventricles, veins, and arterioles?
Why is antagonistic control not seen in ventricles, veins, and arterioles?
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In the context of sympathetic and parasympathetic pathways, what is a significant difference in neurotransmitter usage?
In the context of sympathetic and parasympathetic pathways, what is a significant difference in neurotransmitter usage?
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What triggers the exocytosis of synaptic vesicles at a sympathetic neuroeffector junction?
What triggers the exocytosis of synaptic vesicles at a sympathetic neuroeffector junction?
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What happens to norepinephrine after it activates the adrenergic receptor?
What happens to norepinephrine after it activates the adrenergic receptor?
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What role do voltage-gated Ca2+ channels play in the sympathetic neuroeffector junction?
What role do voltage-gated Ca2+ channels play in the sympathetic neuroeffector junction?
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What is one possible fate of norepinephrine following its release into the synaptic cleft?
What is one possible fate of norepinephrine following its release into the synaptic cleft?
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What initiates the process of norepinephrine release at the sympathetic neuroeffector junction?
What initiates the process of norepinephrine release at the sympathetic neuroeffector junction?
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What is the primary type of receptor that norepinephrine binds to in postganglionic sympathetic target cells?
What is the primary type of receptor that norepinephrine binds to in postganglionic sympathetic target cells?
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What substance is responsible for the removal of norepinephrine from the synapse?
What substance is responsible for the removal of norepinephrine from the synapse?
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Which event directly leads to calcium ion entry in the axon varicosity during norepinephrine release?
Which event directly leads to calcium ion entry in the axon varicosity during norepinephrine release?
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What is the role of norepinephrine (NE) in the sympathetic nervous system?
What is the role of norepinephrine (NE) in the sympathetic nervous system?
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What occurs after norepinephrine has diffused away from the synapse?
What occurs after norepinephrine has diffused away from the synapse?
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What distinguishes selective beta-blockers from non-selective beta-blockers?
What distinguishes selective beta-blockers from non-selective beta-blockers?
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Which neurotransmitter is associated primarily with the parasympathetic pathway?
Which neurotransmitter is associated primarily with the parasympathetic pathway?
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Which receptor subtype is NOT primarily associated with the sympathetic pathway?
Which receptor subtype is NOT primarily associated with the sympathetic pathway?
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What is the result of sympathetic pathway activation?
What is the result of sympathetic pathway activation?
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How do beta-blockers primarily function in the body?
How do beta-blockers primarily function in the body?
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Which type of pathway does the adrenal medulla primarily belong to?
Which type of pathway does the adrenal medulla primarily belong to?
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What type of receptor is primarily found on the target cells of the sympathetic pathway?
What type of receptor is primarily found on the target cells of the sympathetic pathway?
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Which neurotransmitter is NOT typically used in the somatic motor pathway?
Which neurotransmitter is NOT typically used in the somatic motor pathway?
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Which receptor subtype is associated with the effects of epinephrine in the body?
Which receptor subtype is associated with the effects of epinephrine in the body?
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What effect do non-selective beta-blockers have on the body?
What effect do non-selective beta-blockers have on the body?
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What triggers the opening of voltage-gated Ca2+ channels at the sympathetic neuroeffector junction?
What triggers the opening of voltage-gated Ca2+ channels at the sympathetic neuroeffector junction?
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Which enzyme is responsible for the metabolism of norepinephrine?
Which enzyme is responsible for the metabolism of norepinephrine?
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What is the role of tyrosine in the sympathetic neuroeffector junction?
What is the role of tyrosine in the sympathetic neuroeffector junction?
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What happens when an action potential arrives at the varicosity?
What happens when an action potential arrives at the varicosity?
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What is the primary action of norepinephrine at the target cell?
What is the primary action of norepinephrine at the target cell?
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What is the role of the varicosity in the autonomic synapse?
What is the role of the varicosity in the autonomic synapse?
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Which ion's influx is crucial for norepinephrine release?
Which ion's influx is crucial for norepinephrine release?
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Which of the following correctly describes the process of norepinephrine removal?
Which of the following correctly describes the process of norepinephrine removal?
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What occurs to neurotransmitter molecules after they are released into the synaptic cleft?
What occurs to neurotransmitter molecules after they are released into the synaptic cleft?
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What initiates the entire process of norepinephrine release at the sympathetic neuroeffector junction?
What initiates the entire process of norepinephrine release at the sympathetic neuroeffector junction?
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Study Notes
Autonomic and Somatic Motor Control
- Antagonistic control is predominantly observed at the sinoatrial (SA) node, not in ventricles, veins, or arterioles.
- Sympathetic ganglia are organized in two chains flanking the vertebral column.
- The vagus nerve contains approximately 75% of all parasympathetic fibers, transmitting sensory data from internal organs to the brain and sending output from the brain to organs.
Neurotransmitters and Receptors
- Sympathetic pathways utilize norepinephrine (NE) or acetylcholine (ACh).
- Parasympathetic pathways primarily use acetylcholine (ACh).
- Selective beta-blockers influence heart function, while non-selective beta-blockers affect various body areas.
Autonomic Pathways Overview
-
Parasympathetic Pathway:
- Originates from the CNS, synapses at a ganglion.
- Utilizes nicotinic and muscarinic receptors targeting smooth and cardiac muscle, some endocrine and exocrine glands, and adipose tissue.
-
Sympathetic Pathway:
- Initiates in the CNS and releases norepinephrine.
- Targets through α and β adrenergic receptors affecting a wide array of bodily functions.
Comparing Efferent Nervous System Divisions
- A greater number of neurons are present in autonomic pathways compared to somatic motor pathways.
- Somatic motor pathways target muscles directly, while autonomic pathways release neurotransmitters affecting various tissues.
Adrenergic Receptors and Neurotransmitter Function
- Norepinephrine (NE) release at sympathetic neuroeffector junctions occurs through action potentials triggering calcium ion (Ca2+) influx, leading to neurotransmitter exocytosis.
- Binding of NE to adrenergic receptors activates a slower, more prolonged response due to G-protein coupling.
- NE can diffuse away from the synapse, be taken back into synaptic vesicles, or be metabolized by monoamine oxidase (MAO).
Summary of Receptor Dynamics
- All adrenergic receptors are G-protein coupled, resulting in slower onset and offset of physiological responses.
- Increased neurotransmitter concentration can lead to a more robust response in target tissues.
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Description
This quiz delves into the intricacies of autonomic and somatic motor control, exploring key concepts such as antagonistic control, neurotransmitters, and the sympathetic and parasympathetic pathways. Test your knowledge on the roles of various receptors and the impact of selective beta-blockers in heart function. Perfect for those studying neuroanatomy and physiology.
