Autoimmune Hypophysitis: Clinical Pharmacy and Pharmacotherapeutics Quiz

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What is the main cause of secondary adrenal insufficiency?

Dysfunction in the pituitary gland or hypothalamus (correct)

Damage to the adrenal glands

Congenital abnormalities in the adrenal glands

Decreased production of cortisol

Which hormone is responsible for stimulating the adrenal glands to produce cortisol?

Insulin

Thyroid-stimulating hormone (TSH)

Adrenocorticotropic hormone (ACTH) (correct)

Glucagon

What is the main consequence of ACTH insufficiency?

Increased metabolism

Decreased production of cortisol (correct)

Increased stress response

Decreased immune response

Which type of ACTH insufficiency is caused by damage to the adrenal glands themselves?

Primary adrenal insufficiency Signup and view all the answers

What is the main difference between primary and secondary adrenal insufficiency?

The cause of the condition Signup and view all the answers

Which hormone is involved in regulating metabolism, immune response, and stress response?

Cortisol Signup and view all the answers

What is measured in a blood cortisol test?

Cortisol levels Signup and view all the answers

How is the starting dose of Prednisolone calculated for children?

8 mg/m2 body surface area Signup and view all the answers

What is the purpose of an ACTH Stimulation Test?

Measuring cortisol response Signup and view all the answers

Which imaging studies may be conducted to visualize the pituitary gland and adrenal glands?

MRI and CT Scan Signup and view all the answers

What potential complication can arise from autoimmune hypophysitis?

Adrenal crisis Signup and view all the answers

What is the purpose of the CRH Stimulation Test?

Identifying hypothalamus or pituitary gland issues Signup and view all the answers

What hormone is responsible for signaling the adrenal glands to produce cortisol?

Adrenocorticotropic hormone (ACTH) Signup and view all the answers

Which of the following is a potential cause of ACTH deficiency?

All of the above Signup and view all the answers

What is the primary function of cortisol in the body?

Dealing with stress Signup and view all the answers

Which part of the brain is responsible for releasing corticotropin-releasing hormone (CRH)?

Hypothalamus Signup and view all the answers

Which of the following is NOT a symptom of ACTH deficiency mentioned in the text?

Weight gain Signup and view all the answers

What hormone does the pituitary gland release in response to CRH from the hypothalamus?