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Questions and Answers
What is the result of receiving an attenuated vaccine?
What is the result of receiving an attenuated vaccine?
- Severe symptoms compared to actual infections
- Sub-clinical disease with symptoms less intensive compared to actual infections (correct)
- No response to the vaccine
- Full-blown disease with severe symptoms
How has biotechnology been used to attenuate pathogens?
How has biotechnology been used to attenuate pathogens?
- By increasing their virulence
- By deleting all genes
- By duplicating their genetic material
- By adding or 'knocking out' a gene (correct)
Why are mutants ideal as vaccines?
Why are mutants ideal as vaccines?
- They cause severe symptoms
- They are difficult to produce
- They mimic the natural infection process without causing severe symptoms (correct)
- They elicit a weak immune response
What is an advantage of attenuated live vaccines?
What is an advantage of attenuated live vaccines?
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What is the purpose of selectively deleting or mutating genes in pathogens?
What is the purpose of selectively deleting or mutating genes in pathogens?
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What is the outcome of using mutants as vaccines?
What is the outcome of using mutants as vaccines?
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Study Notes
Attenuated Live Vaccines
- Attenuated live vaccines consist of weakened or attenuated organisms that can proliferate and provide a continuous antigen to the host.
- People who receive attenuated vaccines develop sub-clinical disease, with symptoms that are less intensive compared to actual infections.
- Mutants or non-virulent organisms are ideal as vaccines because they mimic the natural infection process without causing the same type of symptoms.
- Biotechnology is used to attenuate pathogens by adding or “knocking out” a gene in these organisms, making them weaker.
Advantages
- Attenuated live vaccines have increased immunogenicity and production of memory cells.
- They provide a continuous source of antigen, which elicits a durable immune response.
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Description
Learn about attenuated live vaccines, how they work, and their benefits in providing a durable immune response. Discover the role of mutants and non-virulent organisms in vaccine development.
