15 Questions
What is the principal effect of Atrial natriuretic peptide (ANP) on the glomerulus?
Inhibition of Na+ and water reabsorption
What triggers the secretion of ANP?
Increased blood volume or pressure
How does ANP affect urine production?
Causes ↑ GFR and ↑ Na + filtration with no compensatory Na + reabsorption in distal nephron
What is the concentration of ANP in plasma in normal humans ingesting moderate amounts of NaCl?
About 5 fmol/mL
Under what condition is ANP secretion increased?
ECF volume increased by infusion of isotonic saline
Which hormone is produced in the heart and secreted when blood volume or pressure is elevated?
Atrial natriuretic peptide (ANP)
What is the net effect of Atrial natriuretic peptide (ANP) on sodium and volume?
Sodium loss and volume loss
What triggers the secretion of B-type natriuretic peptide (BNP)?
Stretching of the ventricles
In which form does Atrial natriuretic peptide (ANP) exist in the brain?
Two forms smaller than circulating ANP
What effect does immersion in water up to the neck have on the secretion of renin and aldosterone?
Decreases renin and aldosterone secretion
What is the primary effect of Atrial natriuretic peptide (ANP) on sodium and water excretion?
Inhibiting Na+ and water reabsorption
What triggers the secretion of Brain-type natriuretic peptide (BNP)?
Stretching of the ventricles
How does immersion in water up to the neck affect the secretion of renin and aldosterone?
Decreases secretion of renin and aldosterone
What is the concentration of Atrial natriuretic peptide (ANP) in plasma in normal humans ingesting moderate amounts of NaCl?
5 fmol/mL
Which hormone antagonizes Angiotensin II's actions and stimulates natriuresis through direct effects on the glomerulus?
Atrial natriuretic peptide (ANP)
Test your knowledge about the atrial natriuretic peptide (ANP), the first natriuretic hormone isolated from the heart. Learn about its characteristics, functions, and secretion in response to elevated blood volume or pressure.
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