ATP and Phosphocreatine in Muscle Cells

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What molecule stores a high-energy phosphate to produce ATP for muscle contractions?

Phosphocreatine

Why might the presence of myocardial creatine kinase in the blood plasma suggest a heart attack?

It signifies the release of an enzyme from damaged heart muscle tissue.

How long does the combination of free ATP and phosphocreatine provide energy for intense exercise?

~15 seconds

Which exercise regimen can increase the amount of phosphocreatine stored in muscles?

High Intensity Interval Training (HIIT)

What is required for the aerobic pathway that produces ATP during exercise?

Oxygen

Which of the following is not a source of glucose during exercise?

ATPase enzyme

Why does oxygen deficit develop at the onset of exercise?

Oxygen consumption is insufficient to meet the energy demands of the working muscle

What is one of the primary reasons for excess oxygen consumption post-exercise?

To metabolize lactate

What stimulates exercise-induced hyperventilation or hyperpnea?

Feedback from mechanoreceptors in muscles

What role do carotid and aortic chemoreceptors play during exercise?

Detect changes in plasma CO2, pH, and O2 levels

Which source provides ATP at the start of exercise?

Phosphocreatine breakdown

What leads to the increase in breathing rate and depth during exercise?

Decrease in blood gases levels (PCO2 and PO2)

What happens to ventilation rate as soon as exercise begins?

It increases

What is the effect of mild to moderate exercise on arterial blood gases?

Arterial pH remains stable

Why does arterial PCO2 decrease slightly during high-intensity exercise?

Due to hyperventilation

What contributes to keeping arterial pH relatively stable during high-intensity exercise?

Hyperventilation and buffering of H+ by plasma proteins and bicarbonate

Why does venous PCO2 increase during exercise?

Increased CO2 production by metabolically active muscle cells

What initiates the cardiovascular responses at the start of exercise?

Signals from proprioceptors and stretch receptors in joints and muscles

What happens to the baroreceptor reflex during exercise?

It is inhibited

How does the inhibition of baroreceptor reflexes occur?

By presynaptic inhibition of the baroreceptor sensory pathway

What signals the CNS to suppress the baroreceptor reflex during exercise?

High CO2 concentration in muscle tissues

What percentage of energy produced by contracting muscles is converted into heat?

75-80%

What physiological response occurs when body temperature increases during exercise?

Activation of sweat glands and skin vasodilation

What is the primary purpose of promoting heat loss through sweat glands and vasodilation during exercise?

To regulate body temperature

How does exercise impact plasma triglyceride levels and LDL-C cholesterol levels?

Decreases them

Which of the following does moderate exercise impact positively?

Improved immune function

What effect does strenuous exercise have on immune function?

Suppresses it

Which neurotransmitter is released in the brain as a result of exercise?

Serotonin

How soon can results in improved blood glucose levels be seen after beginning an exercise regimen?

1 week

What effect does exercise have on the levels of healthy HDL-C cholesterol?

Increases them

Learn about the limited supply of free ATP in muscle cells and how phosphocreatine contributes to the production of ATP for muscle contractions. Understand the role of creatine kinase in mediating the reaction. Explore the significance of myocardial creatine kinase in diagnosing myocardial infarction.

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