2.4 Phosphagen System
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Questions and Answers

Which of the following accurately describes the role and speed of the phosphagen system in providing energy for muscle activity?

  • It provides ATP aerobically and is four times as fast as the oxidative system.
  • It provides ATP anaerobically and is roughly twice as fast as the glycolytic system. (correct)
  • It provides ATP aerobically and is the slowest energy system.
  • It provides ATP anaerobically and is slower than both the glycolytic and oxidative systems.

During a high-intensity exercise lasting 10 seconds, which energy system is predominantly used to supply ATP?

  • Glycolytic system
  • Fatty acid oxidation
  • Oxidative system
  • Phosphagen system (correct)

What is the approximate amount of ATP stored in the body under normal resting conditions, and why is it maintained in small amounts?

  • 1000 to 1200 g, to ensure sufficient energy is always available for high-intensity activities.
  • 500 to 700 g, to provide a stable energy reserve during prolonged periods of fasting.
  • 80 to 100 g, so its relative concentration changes rapidly in response to a minimal ATP decrease. (correct)
  • 200 to 300 g, to allow for constant energy expenditure during low-intensity activities.

How does phosphocreatine (PCr) contribute to ATP resynthesis during muscle activity?

<p>PCr donates a phosphate group to ADP, forming ATP. (B)</p> Signup and view all the answers

Which statement accurately describes the energy derived from phosphocreatine (PCr)?

<p>PCr energy can be used to reassemble ATP. (C)</p> Signup and view all the answers

In the context of coupled reactions within the phosphagen system, which of the following best describes the roles of exergonic and endergonic reactions?

<p>Exergonic reactions release energy from PCr breakdown, while endergonic reactions consume energy to synthesize ATP. (C)</p> Signup and view all the answers

Creatine kinase (CK) is a reversible reaction, what determines the direction of the reaction?

<p>The direction of the reaction depends on the energy need and is directed by the Mass Action Effect. (B)</p> Signup and view all the answers

How does creatine kinase (CK) function differently during high-intensity activity versus recovery from exercise?

<p>During high-intensity activity, CK generates ATP; during recovery, it regenerates PCr. (B)</p> Signup and view all the answers

During high-intensity exercise, what primarily dictates the direction of the creatine kinase (CK) reaction?

<p>The concentration of ATP relative to ADP. (D)</p> Signup and view all the answers

Why is the phosphagen system the predominant energy source at the onset of exercise and during very high-intensity activities?

<p>It can rapidly produce ATP due to its enzymatic reactions being readily available and quickly activated. (D)</p> Signup and view all the answers

How would increasing muscle creatine (Cr) levels through supplementation potentially aid in phosphocreatine (PCr) recovery following high-intensity exercise?

<p>It can help drive the creatine kinase reaction towards PCr synthesis due to the mass action effect. (A)</p> Signup and view all the answers

Following intense exercise, what is the correct sequence of events for phosphagen recovery?

<p>ATP recovery via oxidative phosphorylation, followed by PCr restoration using ATP. (A)</p> Signup and view all the answers

Why is training considered the most effective method for improving the phosphagen system, compared to creatine supplementation alone?

<p>Training enhances the activity and amount of key enzymes, like creatine kinase, and promotes other beneficial adaptations. (B)</p> Signup and view all the answers

A power athlete is considering creatine supplementation. Which of the following statements best describes the expected outcome based on the mass action effect?

<p>Faster restoration of phosphocreatine (PCr) during recovery periods, allowing for more rapid ATP regeneration. (C)</p> Signup and view all the answers

If an athlete performs a maximal intensity sprint, approximately how long will the phosphagen system be able to sustain ATP production before phosphocreatine (PCr) stores are significantly depleted?

<p>3-12 seconds. (C)</p> Signup and view all the answers

Following a high-intensity exercise bout that significantly depletes phosphocreatine (PCr) stores, approximately how long does it take for PCr to be fully restored in the muscle?

<p>8-10 minutes. (A)</p> Signup and view all the answers

Flashcards

Phosphagen System

Provides ATP anaerobically and is the fastest energy system. Fuels maximal intensity activity for up to 12-15 seconds.

Stored ATP

A small quantity of ATP stored in cells, that is continually resynthesized at its rate of use.

Phosphocreatine (PCr)

Cells store 4-6x more PCr than ATP. PCr rapidly provides ATP in the presence of ADP.

PCr Energy Use

Splitting a phosphate from PCr provides energy for ATP resynthesis.

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Creatine Kinase (CK)

An enzyme use to generate ATP during high-intensity activity and regenerate PCr in recovery.

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ATP Storage

The body stores only 80 to 100 g of ATP at any time under normal resting conditions

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Phosphocreatine (PCr)

Also called creatinephosphate (CP)

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Coupled Reaction

Includes both exergonic & endergonic reactions

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Duration of Phosphagen System

The phosphagen system sustains maximal intensity exercise for approximately 3-12 seconds until PCr stores are depleted.

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ATP Recovery

ATP recovery uses oxidative phosphorylation via ATP synthase in the electron transport chain (ETC).

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PCr Restoration

PCr is restored via the creatine kinase reaction, utilizing ATP as a substrate.

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ATP Recovery Time

ATP recovery takes approximately 3-5 minutes.

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PCr Recovery Time

PCr recovery takes place, this takes approximately 8-10 minutes.

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Creatine Supplementation Benefit

Recovery of PCr is faster with creatine supplementation due to an increased muscle creatine concentration [Cr].

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Study Notes

  • The phosphagen system provides ATP anaerobically, and is the fastest energy system.
  • It is roughly twice as fast as the glycolytic system and four times as fast as the oxidative system in providing ATP.
  • It fuels maximal intensity activity for up to 12-15 seconds.
  • The phosphagen system consists of stored ATP and phosphocreatine stores.

Stored ATP

  • Cells contain a small quantity of ATP, so they must continually resynthesize it at its rate of use.
  • The body stores only 80 to 100 g of ATP at any time under normal resting conditions.
  • Maintaining small amounts leads to rapid changes in relative concentration in response to a minimal ATP decrease.
  • ATP lasts only 3-5 seconds at maximal intensity.

Phosphocreatine

  • PCr is also called creatinephosphate (CP).
  • Cells store approximately 4-6 times more PCr than ATP.
  • PCr rapidly provides ATP in the presence of ADP.
  • Energy for ATP resynthesis comes from the anaerobic splitting of a phosphate from PCr.
  • Energy for ATP resynthesis is derived from the anaerobic splitting of a phosphate from PCr.
  • PCr energy cannot be used for cellular work; it reassembles ATP.
  • The PCr reaction is a coupled reaction, including both exergonic and endergonic reactions.
  • Creatine kinase (CK) is a reversible reaction.
  • CK generates ATP during high-intensity activity and regenerates PCr during recovery from exercise.
  • The direction of the reaction depends on the energy need, directed by the Mass Action Effect.
  • PCr provides ATP during maximal intensity exercise until PCr is depleted in about 3-12 seconds of maximal exercise.
  • The maximum energy yield is reached in about 10 seconds.

Recovery for Phosphagens

  • ATP recovery uses oxidative phosphorylation in the electron transport chain (ETC) via the enzyme ATP synthase, taking 3-5 minutes.
  • PCr is restored using ATP as a substrate in the creatine kinase reaction, taking 8-10 minutes.
  • Stored ATP must be recovered first.

Creatine Supplementation

  • Recovery takes 8-10 minutes.
  • Stored ATP must be recovered first.
  • Creatine supplementation increases muscle [Cr], but not [PCr].
  • Based on the Mass Action Effect, creatine supplementation helps recover PCr more quickly.
  • Supplements can help, but the best way to improve the phosphagen system is through training.

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The phosphagen system is the fastest anaerobic energy system, fueling maximal intensity activity for 12-15 seconds. It consists of stored ATP, lasting 3-5 seconds, and phosphocreatine (PCr), which cells store in 4-6 times greater quantities than ATP. PCr rapidly provides ATP in the presence of ADP.

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