22 Questions
Which risk factor for atherosclerosis is considered a major modifiable factor?
Dyslipidemia
What is the primary underlying cause of coronary, cerebral, and peripheral vascular disease according to the text?
Atherosclerosis
Which of the following is NOT considered an emerging risk factor for atherosclerosis?
Diabetes Mellitus
In terms of distribution, which vessels are more prone to developing atherosclerosis?
Arteries larger than 2mm in diameter
What is considered to be the primary response that leads to atherosclerosis?
Endothelial injury
Which of the following is NOT listed as an emerging risk factor for atherosclerosis?
Hypertension
What imparts a red-brown color when superimposed on ulcerated plaques?
Thrombus
Which of the following is NOT one of the three principal components of atherosclerotic plaques?
Cholesterol
What characterizes stable atheromatous plaques?
Minimal inflammation
Which type of plaques are more likely to complicate or rupture?
Vulnerable plaques
What is a common complication associated with hemorrhage into an atherosclerotic plaque?
Rapid plaque expansion
What can result from critical stenosis in atherosclerosis?
Organ atrophy
Which component of atherosclerotic plaques can lead to thromboembolism?
Lipid
What is the primary reason for aneurysmal dilatation of the arterial wall in atherosclerosis?
Loss of elastic tissue in the media
What is the main cause of atherosclerosis according to the model presented?
Accumulation of lipoproteins
Which of the following cell types is NOT involved in the steps of atherosclerosis as described?
B lymphocytes
What is the primary lipid component found in fatty streaks, the precursor lesion to atheroma?
Oxidized LDL
What is the role of foam cells in atherosclerosis progression?
Releasing inflammatory cytokines
What happens as a result of monocyte adhesion to the endothelium during atherosclerosis?
Migration into the intima and differentiation into macrophages
What is the main reason for smooth muscle cell recruitment in atherosclerosis?
Response to platelet adhesion
Which of the following statements about atherosclerotic plaques is TRUE?
They form due to intimal thickening and lipid accumulation.
What characterizes fatty streaks, the precursor lesion to atheroma?
They are composed of lipid-filled foamy macrophages.
Test your knowledge on categorizing risk factors, evaluating morphological changes, and discussing clinicopathological consequences of atherosclerosis. Topics covered include pathogenesis of coronary, cerebral, and peripheral vascular disease.
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